Adaptive Immune System Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-1280218
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Genes

760 proteins participating in the Adaptive Immune System pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ACTR10 actin-related protein 10 homolog (S. cerevisiae)
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ADRM1 adhesion regulating molecule 1
AHCYL1 adenosylhomocysteinase-like 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANAPC1 anaphase promoting complex subunit 1
ANAPC10 anaphase promoting complex subunit 10
ANAPC11 anaphase promoting complex subunit 11
ANAPC13 anaphase promoting complex subunit 13
ANAPC2 anaphase promoting complex subunit 2
ANAPC4 anaphase promoting complex subunit 4
ANAPC5 anaphase promoting complex subunit 5
ANAPC7 anaphase promoting complex subunit 7
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AP1S3 adaptor-related protein complex 1, sigma 3 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARF1 ADP-ribosylation factor 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ASB1 ankyrin repeat and SOCS box containing 1
ASB10 ankyrin repeat and SOCS box containing 10
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASB12 ankyrin repeat and SOCS box containing 12
ASB13 ankyrin repeat and SOCS box containing 13
ASB14 ankyrin repeat and SOCS box containing 14
ASB15 ankyrin repeat and SOCS box containing 15
ASB16 ankyrin repeat and SOCS box containing 16
ASB17 ankyrin repeat and SOCS box containing 17
ASB18 ankyrin repeat and SOCS box containing 18
ASB2 ankyrin repeat and SOCS box containing 2
ASB3 ankyrin repeat and SOCS box containing 3
ASB4 ankyrin repeat and SOCS box containing 4
ASB5 ankyrin repeat and SOCS box containing 5
ASB6 ankyrin repeat and SOCS box containing 6
ASB7 ankyrin repeat and SOCS box containing 7
ASB8 ankyrin repeat and SOCS box containing 8
ASB9 ankyrin repeat and SOCS box containing 9
ATG14 autophagy related 14
ATG7 autophagy related 7
B2M beta-2-microglobulin
BCAP31 B-cell receptor-associated protein 31
BCL10 B-cell CLL/lymphoma 10
BECN1 beclin 1, autophagy related
BLK BLK proto-oncogene, Src family tyrosine kinase
BLMH bleomycin hydrolase
BLNK B-cell linker
BTBD1 BTB (POZ) domain containing 1
BTBD6 BTB (POZ) domain containing 6
BTK Bruton agammaglobulinemia tyrosine kinase
BTLA B and T lymphocyte associated
BTN1A1 butyrophilin, subfamily 1, member A1
BTN2A1 butyrophilin, subfamily 2, member A1
BTN2A2 butyrophilin, subfamily 2, member A2
BTN3A1 butyrophilin, subfamily 3, member A1
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
BTNL2 butyrophilin-like 2
BTNL8 butyrophilin-like 8
BTNL9 butyrophilin-like 9
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C3 complement component 3
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALR calreticulin
CANX calnexin
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CAPZA3 capping protein (actin filament) muscle Z-line, alpha 3
CAPZB capping protein (actin filament) muscle Z-line, beta
CARD11 caspase recruitment domain family, member 11
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBLL2 Cbl proto-oncogene like 2
CCNF cyclin F
CD101 CD101 molecule
CD14 CD14 molecule
CD160 CD160 molecule
CD19 CD19 molecule
CD1A CD1a molecule
CD1B CD1b molecule
CD1C CD1c molecule
CD1D CD1d molecule
CD200 CD200 molecule
CD200R1 CD200 receptor 1
CD207 CD207 molecule, langerin
CD209 CD209 molecule
CD22 CD22 molecule
CD226 CD226 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD300A CD300a molecule
CD300C CD300c molecule
CD300E CD300e molecule
CD300LB CD300 molecule-like family member b
CD300LD CD300 molecule-like family member d
CD300LF CD300 molecule-like family member f
CD300LG CD300 molecule-like family member g
CD33 CD33 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD80 CD80 molecule
CD81 CD81 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CD8B CD8b molecule
CD96 CD96 molecule
CD99 CD99 molecule
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC23 cell division cycle 23
CDC26 cell division cycle 26
CDC27 cell division cycle 27
CDC34 cell division cycle 34
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CENPE centromere protein E, 312kDa
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC2B C-type lectin domain family 2, member B
CLEC2D C-type lectin domain family 2, member D
CLEC4G C-type lectin domain family 4, member G
CLTA clathrin, light chain A
CLTC clathrin, heavy chain (Hc)
COL17A1 collagen, type XVII, alpha 1
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COLEC12 collectin sub-family member 12
CRTAM cytotoxic and regulatory T cell molecule
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSA cathepsin A
CTSB cathepsin B
CTSC cathepsin C
CTSD cathepsin D
CTSE cathepsin E
CTSF cathepsin F
CTSH cathepsin H
CTSK cathepsin K
CTSL cathepsin L
CTSO cathepsin O
CTSS cathepsin S
CTSV cathepsin V
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL5 cullin 5
CUL7 cullin 7
CXADR coxsackie virus and adenovirus receptor
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF1 DDB1 and CUL4 associated factor 1
DCTN1 dynactin 1
DCTN2 dynactin 2 (p50)
DCTN3 dynactin 3 (p22)
DCTN4 dynactin 4 (p62)
DCTN5 dynactin 5 (p25)
DCTN6 dynactin 6
DET1 de-etiolated homolog 1 (Arabidopsis)
DNM1 dynamin 1
DNM2 dynamin 2
DNM3 dynamin 3
DTX3L deltex 3 like, E3 ubiquitin ligase
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLL2 dynein, light chain, LC8-type 2
DZIP3 DAZ interacting zinc finger protein 3
ELOB elongin B
ELOC elongin C
ENAH enabled homolog (Drosophila)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
EVL Enah/Vasp-like
FBXL12 F-box and leucine-rich repeat protein 12
FBXL13 F-box and leucine-rich repeat protein 13
FBXL14 F-box and leucine-rich repeat protein 14
FBXL15 F-box and leucine-rich repeat protein 15
FBXL16 F-box and leucine-rich repeat protein 16
FBXL18 F-box and leucine-rich repeat protein 18
FBXL19 F-box and leucine-rich repeat protein 19
FBXL20 F-box and leucine-rich repeat protein 20
FBXL22 F-box and leucine-rich repeat protein 22
FBXL3 F-box and leucine-rich repeat protein 3
FBXL4 F-box and leucine-rich repeat protein 4
FBXL5 F-box and leucine-rich repeat protein 5
FBXL7 F-box and leucine-rich repeat protein 7
FBXL8 F-box and leucine-rich repeat protein 8
FBXO10 F-box protein 10
FBXO11 F-box protein 11
FBXO15 F-box protein 15
FBXO17 F-box protein 17
FBXO2 F-box protein 2
FBXO21 F-box protein 21
FBXO22 F-box protein 22
FBXO27 F-box protein 27
FBXO30 F-box protein 30
FBXO31 F-box protein 31
FBXO32 F-box protein 32
FBXO4 F-box protein 4
FBXO40 F-box protein 40
FBXO41 F-box protein 41
FBXO44 F-box protein 44
FBXO6 F-box protein 6
FBXO7 F-box protein 7
FBXO9 F-box protein 9
FBXW10 F-box and WD repeat domain containing 10
FBXW11 F-box and WD repeat domain containing 11
FBXW12 F-box and WD repeat domain containing 12
FBXW2 F-box and WD repeat domain containing 2
FBXW4 F-box and WD repeat domain containing 4
FBXW5 F-box and WD repeat domain containing 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
FBXW9 F-box and WD repeat domain containing 9
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FKBP1A FK506 binding protein 1A, 12kDa
FYB1 FYN binding protein 1
FYN FYN proto-oncogene, Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAN gigaxonin
GLMN glomulin, FKBP associated protein
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
HCST hematopoietic cell signal transducer
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HFE hemochromatosis
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DMB major histocompatibility complex, class II, DM beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ICAM5 intercellular adhesion molecule 5, telencephalin
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IFI30 interferon, gamma-inducible protein 30
IFITM1 interferon induced transmembrane protein 1
IGH immunoglobulin heavy locus
IGL immunoglobulin lambda locus
IGLL5 immunoglobulin lambda-like polypeptide 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITCH itchy E3 ubiquitin protein ligase
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB5 integrin, beta 5
ITGB7 integrin, beta 7
ITK IL2-inducible T-cell kinase
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JAML junction adhesion molecule like
KBTBD13 kelch repeat and BTB (POZ) domain containing 13
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KBTBD7 kelch repeat and BTB (POZ) domain containing 7
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KCTD6 potassium channel tetramerization domain containing 6
KCTD7 potassium channel tetramerization domain containing 7
KEAP1 kelch-like ECH-associated protein 1
KIF11 kinesin family member 11
KIF15 kinesin family member 15
KIF18A kinesin family member 18A
KIF20A kinesin family member 20A
KIF22 kinesin family member 22
KIF23 kinesin family member 23
KIF26A kinesin family member 26A
KIF2A kinesin heavy chain member 2A
KIF2B kinesin family member 2B
KIF2C kinesin family member 2C
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
KIF3C kinesin family member 3C
KIF4A kinesin family member 4A
KIF4B kinesin family member 4B
KIF5A kinesin family member 5A
KIF5B kinesin family member 5B
KIF5C kinesin family member 5C
KIFAP3 kinesin-associated protein 3
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
KLC3 kinesin light chain 3
KLC4 kinesin light chain 4
KLHL11 kelch-like family member 11
KLHL13 kelch-like family member 13
KLHL2 kelch-like family member 2
KLHL20 kelch-like family member 20
KLHL21 kelch-like family member 21
KLHL22 kelch-like family member 22
KLHL25 kelch-like family member 25
KLHL3 kelch-like family member 3
KLHL41 kelch-like family member 41
KLHL42 kelch-like family member 42
KLHL5 kelch-like family member 5
KLHL9 kelch-like family member 9
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LAG3 lymphocyte-activation gene 3
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LGMN legumain
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
LMO7 LIM domain 7
LNPEP leucyl/cystinyl aminopeptidase
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LONRF1 LON peptidase N-terminal domain and ring finger 1
LRR1 leucine rich repeat protein 1
LRRC41 leucine rich repeat containing 41
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
LTN1 listerin E3 ubiquitin protein ligase 1
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MALT1 MALT1 paracaspase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MEX3C mex-3 RNA binding family member C
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MIB2 mindbomb E3 ubiquitin protein ligase 2
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MKRN1 makorin ring finger protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MRC1 mannose receptor, C type 1
MRC2 mannose receptor, C type 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYD88 myeloid differentiation primary response 88
MYLIP myosin regulatory light chain interacting protein
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCK1 NCK adaptor protein 1
NCOR2 nuclear receptor corepressor 2
NCR1 natural cytotoxicity triggering receptor 1
NCR2 natural cytotoxicity triggering receptor 2
NCR3 natural cytotoxicity triggering receptor 3
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1
NECTIN2 nectin cell adhesion molecule 2
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NPDC1 neural proliferation, differentiation and control, 1
NPEPPS aminopeptidase puromycin sensitive
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
ORAI1 ORAI calcium release-activated calcium modulator 1
ORAI2 ORAI calcium release-activated calcium modulator 2
OSBPL1A oxysterol binding protein-like 1A
OSCAR osteoclast associated, immunoglobulin-like receptor
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDIA3 protein disulfide isomerase family A, member 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PIANP PILR alpha associated neural protein
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PILRA paired immunoglobin-like type 2 receptor alpha
PILRB paired immunoglobin-like type 2 receptor beta
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPL periplakin
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCB protein kinase C, beta
PRKCQ protein kinase C, theta
PRKG1 protein kinase, cGMP-dependent, type I
PRKN parkin RBR E3 ubiquitin protein ligase
PRR5 proline rich 5 (renal)
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
PVR poliovirus receptor
RAB7A RAB7A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAET1E retinoic acid early transcript 1E
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RAP1GAP2 RAP1 GTPase activating protein 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RBBP6 retinoblastoma binding protein 6
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RICTOR RPTOR independent companion of MTOR, complex 2
RILP Rab interacting lysosomal protein
RIPK2 receptor-interacting serine-threonine kinase 2
RLIM ring finger protein, LIM domain interacting
RNF111 ring finger protein 111
RNF114 ring finger protein 114
RNF115 ring finger protein 115
RNF123 ring finger protein 123
RNF126 ring finger protein 126
RNF130 ring finger protein 130
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RNF14 ring finger protein 14
RNF144B ring finger protein 144B
RNF182 ring finger protein 182
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RNF213 ring finger protein 213
RNF217 ring finger protein 217
RNF220 ring finger protein 220
RNF25 ring finger protein 25
RNF34 ring finger protein 34, E3 ubiquitin protein ligase
RNF4 ring finger protein 4
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNF6 ring finger protein (C3H2C3 type) 6
RNF7 ring finger protein 7
RPS27A ribosomal protein S27a
S100A1 S100 calcium binding protein A1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAR1B secretion associated, Ras related GTPase 1B
SEC13 SEC13 homolog (S. cerevisiae)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SELL selectin L
SEM1 SEM1 26S proteasome subunit
SFTPD surfactant protein D
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SH3GL2 SH3-domain GRB2-like 2
SH3KBP1 SH3-domain kinase binding protein 1
SH3RF1 SH3 domain containing ring finger 1
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIGLEC10 sialic acid binding Ig-like lectin 10
SIGLEC11 sialic acid binding Ig-like lectin 11
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene)
SIGLEC5 sialic acid binding Ig-like lectin 5
SIGLEC6 sialic acid binding Ig-like lectin 6
SIGLEC7 sialic acid binding Ig-like lectin 7
SIGLEC8 sialic acid binding Ig-like lectin 8
SIGLEC9 sialic acid binding Ig-like lectin 9
SIPA1 signal-induced proliferation-associated 1
SKP1 S-phase kinase-associated protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAMF6 SLAM family member 6
SLAMF7 SLAM family member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAP23 synaptosomal-associated protein, 23kDa
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOS1 son of sevenless homolog 1 (Drosophila)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2
SPSB4 splA/ryanodine receptor domain and SOCS box containing 4
SPTBN2 spectrin, beta, non-erythrocytic 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STIM1 stromal interaction molecule 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX4 syntaxin 4
SYK spleen tyrosine kinase
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
THEM4 thioesterase superfamily member 4
THOP1 thimet oligopeptidase 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TPP2 tripeptidyl peptidase II
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRAT1 T cell receptor associated transmembrane adaptor 1
TREM1 triggering receptor expressed on myeloid cells 1
TREM2 triggering receptor expressed on myeloid cells 2
TREML1 triggering receptor expressed on myeloid cells-like 1
TREML2 triggering receptor expressed on myeloid cells-like 2
TREML4 triggering receptor expressed on myeloid cells-like 4
TRIB3 tribbles pseudokinase 3
TRIM11 tripartite motif containing 11
TRIM21 tripartite motif containing 21
TRIM32 tripartite motif containing 32
TRIM36 tripartite motif containing 36
TRIM37 tripartite motif containing 37
TRIM39 tripartite motif containing 39
TRIM4 tripartite motif containing 4
TRIM41 tripartite motif containing 41
TRIM50 tripartite motif containing 50
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRIM69 tripartite motif containing 69
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TRIM9 tripartite motif containing 9
TRIP12 thyroid hormone receptor interactor 12
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA3E tubulin, alpha 3e
TUBA4A tubulin, alpha 4a
TUBA4B tubulin, alpha 4b
TUBA8 tubulin, alpha 8
TUBAL3 tubulin, alpha-like 3
TUBB1 tubulin, beta 1 class VI
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB4A tubulin, beta 4A class IVa
TUBB4B tubulin, beta 4B class IVb
TUBB6 tubulin, beta 6 class V
TUBB8 tubulin, beta 8 class VIII
TUBB8B tubulin beta 8B
TYROBP TYRO protein tyrosine kinase binding protein
UBA1 ubiquitin-like modifier activating enzyme 1
UBA3 ubiquitin-like modifier activating enzyme 3
UBA5 ubiquitin-like modifier activating enzyme 5
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBA6 ubiquitin-like modifier activating enzyme 6
UBA7 ubiquitin-like modifier activating enzyme 7
UBAC1 UBA domain containing 1
UBB ubiquitin B
UBC ubiquitin C
UBE2A ubiquitin-conjugating enzyme E2A
UBE2B ubiquitin-conjugating enzyme E2B
UBE2C ubiquitin-conjugating enzyme E2C
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE2D3 ubiquitin-conjugating enzyme E2D 3
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBE2E2 ubiquitin-conjugating enzyme E2E 2
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBE2G1 ubiquitin-conjugating enzyme E2G 1
UBE2G2 ubiquitin-conjugating enzyme E2G 2
UBE2H ubiquitin-conjugating enzyme E2H
UBE2J1 ubiquitin-conjugating enzyme E2, J1
UBE2J2 ubiquitin-conjugating enzyme E2, J2
UBE2K ubiquitin-conjugating enzyme E2K
UBE2L3 ubiquitin-conjugating enzyme E2L 3
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2M ubiquitin-conjugating enzyme E2M
UBE2N ubiquitin-conjugating enzyme E2N
UBE2O ubiquitin-conjugating enzyme E2O
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
UBE2Q2 ubiquitin-conjugating enzyme E2Q family member 2
UBE2R2 ubiquitin-conjugating enzyme E2R 2
UBE2S ubiquitin-conjugating enzyme E2S
UBE2U ubiquitin-conjugating enzyme E2U (putative)
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBE2Z ubiquitin-conjugating enzyme E2Z
UBE3A ubiquitin protein ligase E3A
UBE3B ubiquitin protein ligase E3B
UBE3C ubiquitin protein ligase E3C
UBE3D ubiquitin protein ligase E3D
UBE4A ubiquitination factor E4A
UBOX5 U-box domain containing 5
UBR1 ubiquitin protein ligase E3 component n-recognin 1
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UFL1 UFM1-specific ligase 1
ULBP1 UL16 binding protein 1
ULBP3 UL16 binding protein 3
UNKL unkempt family zinc finger-like
VAMP3 vesicle-associated membrane protein 3
VAMP8 vesicle-associated membrane protein 8
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WAS Wiskott-Aldrich syndrome
WSB1 WD repeat and SOCS box containing 1
WWP1 WW domain containing E3 ubiquitin protein ligase 1
XDH xanthine dehydrogenase
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB16 zinc finger and BTB domain containing 16
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase