| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PODXL | podocalyxin-like | 0.138151 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.118784 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.10158 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.098959 |
| CALR | calreticulin | 0.0943549 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0930086 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0788493 |
| NDRG1 | N-myc downstream regulated 1 | 0.0774712 |
| B2M | beta-2-microglobulin | 0.0748449 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0696005 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0644645 |
| UBC | ubiquitin C | 0.0636209 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0617724 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.060759 |
| FLNB | filamin B, beta | 0.0573907 |
| CD44 | CD44 molecule (Indian blood group) | 0.0568331 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.056452 |
| ANXA2 | annexin A2 | 0.0552987 |
| LDHA | lactate dehydrogenase A | 0.0524335 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0492022 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.046431 |
| POTEF | POTE ankyrin domain family, member F | 0.0424019 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0415372 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0411823 |
| COL5A1 | collagen, type V, alpha 1 | 0.0397112 |
| TPM3 | tropomyosin 3 | 0.0386423 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0379943 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0370557 |
| GOLGA4 | golgin A4 | 0.0363894 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0363763 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0361716 |
| PKM | pyruvate kinase, muscle | 0.0360521 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.035506 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0353264 |
| HELZ | helicase with zinc finger | 0.0343175 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0341886 |
| ADM | adrenomedullin | 0.0335197 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0332245 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0329645 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.032077 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.031223 |
| PLEC | plectin | 0.0312145 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0308836 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0305659 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0302278 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0295137 |
| THBS2 | thrombospondin 2 | 0.0294028 |
| SQSTM1 | sequestosome 1 | 0.028767 |
| SEPTIN9 | septin 9 | 0.0286782 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0286306 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0285674 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0283377 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0281652 |
| AXL | AXL receptor tyrosine kinase | 0.0281473 |
| CANX | calnexin | 0.0280764 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275387 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0269654 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0265986 |
| RTN4 | reticulon 4 | 0.0264851 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.02641 |
| FAM107B | family with sequence similarity 107, member B | 0.0259392 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0258383 |
| RAI1 | retinoic acid induced 1 | 0.0257968 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0257664 |
| RNF24 | ring finger protein 24 | 0.025462 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0253594 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0252933 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0252741 |
| FLNA | filamin A, alpha | 0.0252061 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0245288 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.024401 |
| SUCO | SUN domain containing ossification factor | 0.0243335 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0243312 |
| ASPH | aspartate beta-hydroxylase | 0.0243175 |
| MXI1 | MAX interactor 1, dimerization protein | 0.024094 |
| APP | amyloid beta (A4) precursor protein | 0.0238982 |
| ZNF292 | zinc finger protein 292 | 0.0236801 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0234258 |
| CENPF | centromere protein F, 350/400kDa | 0.0233298 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0230645 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0228033 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.022789 |
| AHNAK | AHNAK nucleoprotein | 0.0227847 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0227559 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0226842 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0225273 |
| COPA | coatomer protein complex, subunit alpha | 0.0224938 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0223887 |
| MB21D2 | Mab-21 domain containing 2 | 0.0223792 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0223672 |
| MKI67 | marker of proliferation Ki-67 | 0.0222544 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0219902 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0217591 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0217439 |
| RND3 | Rho family GTPase 3 | 0.0215758 |
| USP3 | ubiquitin specific peptidase 3 | 0.0215403 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0215311 |
| C1D | C1D nuclear receptor corepressor | 0.0213479 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0211853 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0211697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.179647 |
| VIM | vimentin | -0.155637 |
| SUCNR1 | succinate receptor 1 | -0.0810839 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0793159 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0615698 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0611223 |
| COL1A2 | collagen, type I, alpha 2 | -0.0564176 |
| MT2A | metallothionein 2A | -0.0561897 |
| MX2 | MX dynamin-like GTPase 2 | -0.0520865 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.049071 |
| FBN1 | fibrillin 1 | -0.0470309 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.045101 |
| PLAT | plasminogen activator, tissue | -0.0421849 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0407546 |
| HLA-B | major histocompatibility complex, class I, B | -0.0407398 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0393439 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0382546 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0366173 |
| PRSS23 | protease, serine, 23 | -0.0344072 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0336435 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0335649 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0333355 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0319697 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0303313 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0291923 |
| VCL | vinculin | -0.0287189 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0277385 |
| NAV1 | neuron navigator 1 | -0.0265257 |
| EHBP1 | EH domain binding protein 1 | -0.0261131 |
| MT1X | metallothionein 1X | -0.0256357 |
| COL3A1 | collagen, type III, alpha 1 | -0.025208 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0248979 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0247166 |
| S100A11 | S100 calcium binding protein A11 | -0.0243574 |
| MEIS2 | Meis homeobox 2 | -0.0241076 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0239859 |
| GPC6 | glypican 6 | -0.02383 |
| SP100 | SP100 nuclear antigen | -0.0236874 |
| TPM1 | tropomyosin 1 (alpha) | -0.0236604 |
| RIGI | RNA sensor RIG-I | -0.0234877 |
| FN1 | fibronectin 1 | -0.0233353 |
| S100A4 | S100 calcium binding protein A4 | -0.023004 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0225298 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0215203 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0211517 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0209229 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0204895 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0202542 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.020247 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0202461 |
| INTS6 | integrator complex subunit 6 | -0.0199864 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0196286 |
| FRMD5 | FERM domain containing 5 | -0.0192389 |
| CUX1 | cut-like homeobox 1 | -0.0191334 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0190072 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0188399 |
| CD81 | CD81 molecule | -0.0187677 |
| CDK13 | cyclin-dependent kinase 13 | -0.018767 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0184643 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0183825 |
| TBCA | tubulin folding cofactor A | -0.0179154 |
| RBM25 | RNA binding motif protein 25 | -0.0178404 |
| JAZF1 | JAZF zinc finger 1 | -0.0176618 |
| KRT81 | keratin 81, type II | -0.0174877 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0172858 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0170497 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0169672 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0168842 |
| TAGLN2 | transgelin 2 | -0.0166532 |
| COL1A1 | collagen, type I, alpha 1 | -0.0165505 |
| COL5A2 | collagen, type V, alpha 2 | -0.0165391 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0161232 |
| BPTF | bromodomain PHD finger transcription factor | -0.0160825 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0160229 |
| CBX3 | chromobox homolog 3 | -0.0158815 |
| SYT1 | synaptotagmin I | -0.0158158 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0155621 |
| PMP22 | peripheral myelin protein 22 | -0.0154782 |
| AEBP2 | AE binding protein 2 | -0.0154766 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0152965 |
| PLSCR1 | phospholipid scramblase 1 | -0.015181 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.014998 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0149968 |
| HOXD10 | homeobox D10 | -0.0148989 |
| TENM3 | teneurin transmembrane protein 3 | -0.0147125 |
| PFN1 | profilin 1 | -0.0146395 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0146324 |
| HLA-C | major histocompatibility complex, class I, C | -0.0144789 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0144599 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0142425 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0142273 |
| FRMD4A | FERM domain containing 4A | -0.0141003 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0138664 |
| CDK6 | cyclin-dependent kinase 6 | -0.0137981 |
| RASAL2 | RAS protein activator like 2 | -0.0137893 |
| PRRX1 | paired related homeobox 1 | -0.0136852 |
| RPS19 | ribosomal protein S19 | -0.0135082 |
| ECM1 | extracellular matrix protein 1 | -0.0134818 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.0134688 |
| RNF213 | ring finger protein 213 | -0.0134179 |
