| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.116778 |
| NLGN1 | neuroligin 1 | 0.0822847 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0813409 |
| HMGA2 | high mobility group AT-hook 2 | 0.071491 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0538066 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0485809 |
| ACTG1 | actin gamma 1 | 0.0482788 |
| MMP12 | matrix metallopeptidase 12 | 0.0442069 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0439188 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.041566 |
| EHBP1 | EH domain binding protein 1 | 0.0404807 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0391382 |
| NHSL1 | NHS-like 1 | 0.0361754 |
| YAP1 | Yes-associated protein 1 | 0.0348033 |
| BCHE | butyrylcholinesterase | 0.0326895 |
| MAP1B | microtubule-associated protein 1B | 0.032514 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.032306 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0319499 |
| EGR1 | early growth response 1 | 0.0289214 |
| ANK2 | ankyrin 2, neuronal | 0.0285911 |
| CUX1 | cut-like homeobox 1 | 0.0276027 |
| PCDH7 | protocadherin 7 | 0.027047 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0269564 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0264066 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0261979 |
| POTEF | POTE ankyrin domain family, member F | 0.0260795 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0258084 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0246716 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0220406 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0217827 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0215239 |
| ASPH | aspartate beta-hydroxylase | 0.0213123 |
| NAV3 | neuron navigator 3 | 0.0205992 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0205787 |
| RASAL2 | RAS protein activator like 2 | 0.0199261 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0197834 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0197538 |
| JMJD1C | jumonji domain containing 1C | 0.0194248 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.019093 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0188654 |
| TPM3 | tropomyosin 3 | 0.018545 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0181665 |
| ADIPOR2 | adiponectin receptor 2 | 0.0180337 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0176551 |
| MTAP | methylthioadenosine phosphorylase | 0.0174328 |
| CCN2 | cellular communication network factor 2 | 0.0171796 |
| TPM4 | tropomyosin 4 | 0.0171072 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0170276 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0166732 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0166188 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0163973 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0162566 |
| CANX | calnexin | 0.0159213 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0157661 |
| ATP9A | ATPase, class II, type 9A | 0.0156646 |
| EXOC4 | exocyst complex component 4 | 0.0156307 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0155742 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0154164 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | 0.0154097 |
| MKI67 | marker of proliferation Ki-67 | 0.015258 |
| SETX | senataxin | 0.0149339 |
| ETV6 | ets variant 6 | 0.0146731 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.014558 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.014494 |
| IPO7 | importin 7 | 0.0143059 |
| TMEM41B | transmembrane protein 41B | 0.0139479 |
| PRDX1 | peroxiredoxin 1 | 0.0138876 |
| OSMR | oncostatin M receptor | 0.0138355 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0136026 |
| CALR | calreticulin | 0.0134927 |
| TUBA1B | tubulin, alpha 1b | 0.0134438 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0134182 |
| BRI3BP | BRI3 binding protein | 0.0134133 |
| PRKCE | protein kinase C, epsilon | 0.0134021 |
| PDGFC | platelet derived growth factor C | 0.0133415 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0132085 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0131042 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0130566 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0129723 |
| DST | dystonin | 0.0129348 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.012879 |
| EGFR | epidermal growth factor receptor | 0.0128667 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0128464 |
| COL5A2 | collagen, type V, alpha 2 | 0.0122996 |
| GCG | glucagon | 0.0122914 |
| RRM2 | ribonucleotide reductase M2 | 0.012166 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0121345 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0119989 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.011624 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0116022 |
| DIAPH2 | diaphanous-related formin 2 | 0.0115552 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | 0.0115402 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0115346 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.011508 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0114678 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0114272 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0113024 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0110618 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0110053 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0109748 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | -0.181917 |
| VIM | vimentin | -0.152716 |
| TMSB10 | thymosin beta 10 | -0.134119 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0813091 |
| PCBP2 | poly(rC) binding protein 2 | -0.0791633 |
| RPS27A | ribosomal protein S27a | -0.0762299 |
| UBC | ubiquitin C | -0.0651935 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0615449 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0483334 |
| RPL23 | ribosomal protein L23 | -0.0468951 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0439246 |
| PTMA | prothymosin, alpha | -0.0429861 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0429157 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0426327 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0421108 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0413129 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0386691 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0363486 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0359959 |
| CPOX | coproporphyrinogen oxidase | -0.0353768 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0344212 |
| MED13L | mediator complex subunit 13-like | -0.0340246 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0334867 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0333459 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0330765 |
| ZNF292 | zinc finger protein 292 | -0.0325621 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0322466 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0297895 |
| RPLP2 | ribosomal protein, large, P2 | -0.0286921 |
| RPL19 | ribosomal protein L19 | -0.028478 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0277989 |
| MGAT4C | MGAT4 family, member C | -0.0276398 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0270181 |
| ECT2 | epithelial cell transforming 2 | -0.0270169 |
| FTL | ferritin, light polypeptide | -0.0269661 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0268387 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0265415 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0263538 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0257499 |
| RPS3 | ribosomal protein S3 | -0.0257424 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0255558 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0253419 |
| NEK7 | NIMA-related kinase 7 | -0.025037 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0247544 |
| USP34 | ubiquitin specific peptidase 34 | -0.0246584 |
| XPO1 | exportin 1 | -0.0242194 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0240011 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0239781 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0238283 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0236244 |
| SYT1 | synaptotagmin I | -0.0234806 |
| YBX1 | Y box binding protein 1 | -0.0233794 |
| RPL26 | ribosomal protein L26 | -0.0233605 |
| KLHL24 | kelch-like family member 24 | -0.023293 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0232669 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0230865 |
| EDN1 | endothelin 1 | -0.0230098 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0226783 |
| PCM1 | pericentriolar material 1 | -0.0224068 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0223425 |
| KIF5B | kinesin family member 5B | -0.0223341 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0221936 |
| CCNL1 | cyclin L1 | -0.0220595 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0219289 |
| RPS12 | ribosomal protein S12 | -0.0216211 |
| RBM27 | RNA binding motif protein 27 | -0.0214821 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0214631 |
| SPAG9 | sperm associated antigen 9 | -0.0212497 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0207594 |
| OXR1 | oxidation resistance 1 | -0.0206189 |
| TNPO1 | transportin 1 | -0.0205096 |
| NF1 | neurofibromin 1 | -0.0204306 |
| TXNRD1 | thioredoxin reductase 1 | -0.0203311 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0203006 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0202168 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0200786 |
| AHNAK | AHNAK nucleoprotein | -0.019966 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0198813 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0198364 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0197819 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0197151 |
| CEP192 | centrosomal protein 192kDa | -0.0197133 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -0.019533 |
| RPL8 | ribosomal protein L8 | -0.019498 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0194904 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0192813 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0191946 |
| USP15 | ubiquitin specific peptidase 15 | -0.0191833 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0191752 |
| CCNI | cyclin I | -0.019165 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0191612 |
| RPS21 | ribosomal protein S21 | -0.0187928 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0187786 |
| OGA | O-GlcNAcase | -0.0187595 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0187254 |
| TFG | TRK-fused gene | -0.0186557 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0186109 |
| RPS19 | ribosomal protein S19 | -0.0185799 |
| CLDN1 | claudin 1 | -0.0185776 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0185692 |
