| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Adenine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.098195 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0786932 |
| RNF213 | ring finger protein 213 | 0.0702883 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0690054 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0649498 |
| MX1 | MX dynamin-like GTPase 1 | 0.0624541 |
| RAD51B | RAD51 paralog B | 0.0618249 |
| ATP11A | ATPase, class VI, type 11A | 0.0538939 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0517707 |
| PHF3 | PHD finger protein 3 | 0.0481403 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0481157 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0474824 |
| EPHB2 | EPH receptor B2 | 0.0472425 |
| BCL2L1 | BCL2-like 1 | 0.0467676 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0455902 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0443202 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.043267 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0432465 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0414835 |
| RIGI | RNA sensor RIG-I | 0.0410099 |
| TNS4 | tensin 4 | 0.0400853 |
| MLPH | melanophilin | 0.038665 |
| ATP10B | ATPase, class V, type 10B | 0.0383794 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0382011 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0381854 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0379894 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0357876 |
| PTK2 | protein tyrosine kinase 2 | 0.0349862 |
| STK24 | serine/threonine kinase 24 | 0.034942 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0348735 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0336367 |
| MAP7 | microtubule-associated protein 7 | 0.0330986 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0324206 |
| PRKCE | protein kinase C, epsilon | 0.0311708 |
| PLSCR1 | phospholipid scramblase 1 | 0.0309916 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.030192 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0301814 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0297071 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0293394 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0291855 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0286525 |
| RBM26 | RNA binding motif protein 26 | 0.0279592 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0271459 |
| DIAPH1 | diaphanous-related formin 1 | 0.0269117 |
| ETV6 | ets variant 6 | 0.0267015 |
| HDAC4 | histone deacetylase 4 | 0.0256525 |
| LYZ | lysozyme | 0.0255717 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0251357 |
| TRERF1 | transcriptional regulating factor 1 | 0.0249821 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0246549 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0245445 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0244892 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0242001 |
| ITGA6 | integrin, alpha 6 | 0.0228984 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0228627 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.022573 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0222715 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0222503 |
| TMEM45B | transmembrane protein 45B | 0.0220735 |
| TMEM62 | transmembrane protein 62 | 0.0218877 |
| MYO5B | myosin VB | 0.0218638 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0218496 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0213867 |
| TXNRD1 | thioredoxin reductase 1 | 0.0213038 |
| SPATA6L | spermatogenesis associated 6-like | 0.0212064 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0208709 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0208685 |
| ABHD17C | abhydrolase domain containing 17C | 0.0207391 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0207353 |
| MX2 | MX dynamin-like GTPase 2 | 0.0205917 |
| SAMHD1 | SAM domain and HD domain 1 | 0.0205643 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0205361 |
| KIF16B | kinesin family member 16B | 0.0204083 |
| ANXA11 | annexin A11 | 0.0204021 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0204017 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0203844 |
| DGKH | diacylglycerol kinase, eta | 0.0202847 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.020228 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0200577 |
| IFNGR1 | interferon gamma receptor 1 | 0.0200185 |
| EXOC4 | exocyst complex component 4 | 0.0199826 |
| PTGR1 | prostaglandin reductase 1 | 0.0196844 |
| FAT1 | FAT atypical cadherin 1 | 0.0196209 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0195196 |
| PADI1 | peptidyl arginine deiminase, type I | 0.019514 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0194716 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0192951 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0192708 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0192013 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0191769 |
| EFNA5 | ephrin-A5 | 0.0189829 |
| CCND3 | cyclin D3 | 0.0188826 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0188222 |
| TMPRSS2 | transmembrane protease, serine 2 | 0.0186643 |
| SP100 | SP100 nuclear antigen | 0.018553 |
| AOPEP | aminopeptidase O (putative) | 0.018524 |
| SEPTIN9 | septin 9 | 0.0184722 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0184548 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0182288 |
| MYO1D | myosin ID | 0.0181934 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.198375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.165706 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155787 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155194 |
| B2M | beta-2-microglobulin | -0.131555 |
| LMO7 | LIM domain 7 | -0.100309 |
| HLA-B | major histocompatibility complex, class I, B | -0.0954405 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0850594 |
| SQSTM1 | sequestosome 1 | -0.0772806 |
| MYO1E | myosin IE | -0.0770888 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0764673 |
| NDRG1 | N-myc downstream regulated 1 | -0.0738091 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0727188 |
| EZR | ezrin | -0.0689961 |
| EGR1 | early growth response 1 | -0.068531 |
| PERP | PERP, TP53 apoptosis effector | -0.0614189 |
| FTL | ferritin, light polypeptide | -0.0608102 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0608059 |
| PTMA | prothymosin, alpha | -0.0601668 |
| RPL35A | ribosomal protein L35a | -0.0580253 |
| H1-0 | H1.0 linker histone | -0.058011 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0579305 |
| UBC | ubiquitin C | -0.0576163 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0560345 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0555667 |
| RPS6 | ribosomal protein S6 | -0.0549494 |
| INTS6 | integrator complex subunit 6 | -0.0535392 |
| IRF1 | interferon regulatory factor 1 | -0.0523982 |
| RPLP1 | ribosomal protein, large, P1 | -0.0519091 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0507891 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0495962 |
| RPL34 | ribosomal protein L34 | -0.048041 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0477609 |
| PKM | pyruvate kinase, muscle | -0.047397 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0465511 |
| MORF4L2 | mortality factor 4 like 2 | -0.0463043 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0458387 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0452841 |
| RPL19 | ribosomal protein L19 | -0.0445969 |
| KLF6 | Kruppel-like factor 6 | -0.0436005 |
| ANXA2 | annexin A2 | -0.04236 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0423584 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0423381 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0421208 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0419879 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0419346 |
| HLA-C | major histocompatibility complex, class I, C | -0.0416664 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0413184 |
| TMSB10 | thymosin beta 10 | -0.0408457 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0389972 |
| S100A10 | S100 calcium binding protein A10 | -0.0389842 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0388349 |
| CANX | calnexin | -0.0387722 |
| RRBP1 | ribosome binding protein 1 | -0.0382772 |
| RPS19 | ribosomal protein S19 | -0.03819 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0381339 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0380572 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0379984 |
| RPL12 | ribosomal protein L12 | -0.0376545 |
| ABLIM1 | actin binding LIM protein 1 | -0.0366993 |
| MT2A | metallothionein 2A | -0.0362353 |
| GOLGB1 | golgin B1 | -0.0361431 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0360668 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0357888 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0357115 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0354095 |
| AGR2 | anterior gradient 2 | -0.0353881 |
| AHI1 | Abelson helper integration site 1 | -0.0349861 |
| S100A6 | S100 calcium binding protein A6 | -0.034929 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0349216 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0346209 |
| JUN | jun proto-oncogene | -0.0344305 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0341769 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0341069 |
| HLA-A | major histocompatibility complex, class I, A | -0.0338574 |
| RPL23 | ribosomal protein L23 | -0.0338361 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0338132 |
| DSTN | destrin (actin depolymerizing factor) | -0.0337925 |
| RPS8 | ribosomal protein S8 | -0.0336864 |
| H3-3B | H3.3 histone B | -0.0336679 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0336539 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0334721 |
| CSTB | cystatin B (stefin B) | -0.0328485 |
| TXNIP | thioredoxin interacting protein | -0.0328055 |
| AREG | amphiregulin | -0.0326558 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0323545 |
| LCN2 | lipocalin 2 | -0.0321214 |
| TRIM2 | tripartite motif containing 2 | -0.0314817 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0313608 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0308434 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.030322 |
| GNAS | GNAS complex locus | -0.0301554 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.029826 |
| ENO1 | enolase 1, (alpha) | -0.0297612 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0294871 |
| HDLBP | high density lipoprotein binding protein | -0.0289484 |
| EPCAM | epithelial cell adhesion molecule | -0.0289145 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0288937 |
| PLIN2 | perilipin 2 | -0.0287677 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.028749 |
