| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.215408 |
| VEGFA | vascular endothelial growth factor A | 0.153205 |
| COL6A3 | collagen, type VI, alpha 3 | 0.153126 |
| NDRG1 | N-myc downstream regulated 1 | 0.122842 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0791379 |
| PLEC | plectin | 0.0645265 |
| CADM1 | cell adhesion molecule 1 | 0.0575572 |
| COL5A1 | collagen, type V, alpha 1 | 0.0514963 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0511833 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0499363 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0491762 |
| CALR | calreticulin | 0.0467632 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0450191 |
| NAV2 | neuron navigator 2 | 0.0415872 |
| RPL35A | ribosomal protein L35a | 0.0383685 |
| LOXL2 | lysyl oxidase-like 2 | 0.037925 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0375183 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0361171 |
| CDH13 | cadherin 13 | 0.0355453 |
| PDE10A | phosphodiesterase 10A | 0.0354298 |
| RPL37A | ribosomal protein L37a | 0.03508 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0340401 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0331435 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0329514 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0328351 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0322664 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0321314 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0319449 |
| FTL | ferritin, light polypeptide | 0.0316078 |
| RPS8 | ribosomal protein S8 | 0.0310394 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0307405 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0307225 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0301457 |
| TNS1 | tensin 1 | 0.0291776 |
| PTK2 | protein tyrosine kinase 2 | 0.0289847 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0280313 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0279706 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0274625 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0269908 |
| RPS6 | ribosomal protein S6 | 0.0266683 |
| EGFR | epidermal growth factor receptor | 0.0265812 |
| EFNA5 | ephrin-A5 | 0.0265408 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0263788 |
| GOLGA4 | golgin A4 | 0.026324 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0262905 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0261872 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0260694 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0256281 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0252287 |
| GOLGB1 | golgin B1 | 0.0252102 |
| CMIP | c-Maf inducing protein | 0.0248507 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0245895 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0241022 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0240058 |
| FMNL2 | formin-like 2 | 0.0236306 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0230374 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0229922 |
| MRTFA | myocardin related transcription factor A | 0.0227645 |
| RPL37 | ribosomal protein L37 | 0.0227516 |
| MTDH | metadherin | 0.0224401 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0222906 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0214367 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0209927 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0208374 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0207944 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0206341 |
| CDK13 | cyclin-dependent kinase 13 | 0.0201602 |
| RPL31 | ribosomal protein L31 | 0.020157 |
| FAM219A | family with sequence similarity 219, member A | 0.0199657 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0199075 |
| CCNY | cyclin Y | 0.0197246 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0197182 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0194922 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0193244 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0190546 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0188966 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0187833 |
| ARF4 | ADP-ribosylation factor 4 | 0.0186858 |
| HM13 | histocompatibility (minor) 13 | 0.0186034 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0184237 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0183041 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0182603 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0180759 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0180145 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0179507 |
| MYO9B | myosin IXB | 0.0178825 |
| ADM | adrenomedullin | 0.0174006 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0173546 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0172926 |
| HMBOX1 | homeobox containing 1 | 0.0171575 |
| HYOU1 | hypoxia up-regulated 1 | 0.0169234 |
| COPA | coatomer protein complex, subunit alpha | 0.0168456 |
| PGM3 | phosphoglucomutase 3 | 0.0167561 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0165764 |
| CD44 | CD44 molecule (Indian blood group) | 0.0165621 |
| RUNX1 | runt-related transcription factor 1 | 0.0164855 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0164244 |
| YEATS2 | YEATS domain containing 2 | 0.0163371 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0162803 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0162656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.169413 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.139048 |
| MT2A | metallothionein 2A | -0.12621 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113248 |
| COL1A1 | collagen, type I, alpha 1 | -0.0942357 |
| COL1A2 | collagen, type I, alpha 2 | -0.0900078 |
| FN1 | fibronectin 1 | -0.0882024 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0856575 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0716671 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0650131 |
| TMSB10 | thymosin beta 10 | -0.0639281 |
| VCAN | versican | -0.0618016 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0605793 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0605407 |
| MAP1B | microtubule-associated protein 1B | -0.0586215 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.057331 |
| MT1X | metallothionein 1X | -0.0566443 |
| LOX | lysyl oxidase | -0.0497153 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0489729 |
| INHBA | inhibin, beta A | -0.0474228 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0470251 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0458235 |
| TMSB4X | thymosin beta 4, X-linked | -0.0447501 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0384435 |
| VCL | vinculin | -0.0376764 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0373854 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0362448 |
| CALD1 | caldesmon 1 | -0.0360596 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0358649 |
| KLF6 | Kruppel-like factor 6 | -0.0350828 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0341482 |
| LDHA | lactate dehydrogenase A | -0.0337759 |
| STC1 | stanniocalcin 1 | -0.0333661 |
| TPM4 | tropomyosin 4 | -0.0330899 |
| FBN1 | fibrillin 1 | -0.032762 |
| HMGA1 | high mobility group AT-hook 1 | -0.0323942 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0321623 |
| RIGI | RNA sensor RIG-I | -0.03108 |
| TAGLN2 | transgelin 2 | -0.030702 |
| S100A10 | S100 calcium binding protein A10 | -0.0305705 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.029287 |
| PFN1 | profilin 1 | -0.0286898 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0283795 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0281424 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0278576 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.026344 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0252529 |
| PRSS23 | protease, serine, 23 | -0.0248085 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0244186 |
| ANXA2 | annexin A2 | -0.0242508 |
| ACTG1 | actin gamma 1 | -0.0240074 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.023945 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0238153 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0237352 |
| FOXP1 | forkhead box P1 | -0.0232323 |
| TUBB | tubulin, beta class I | -0.0228896 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0226994 |
| IL6ST | interleukin 6 signal transducer | -0.022396 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0221264 |
| HMCN1 | hemicentin 1 | -0.0213735 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0212622 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0210611 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0208358 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0207553 |
| CAVIN1 | caveolae associated protein 1 | -0.0207282 |
| SMC4 | structural maintenance of chromosomes 4 | -0.020523 |
| IER3 | immediate early response 3 | -0.0204493 |
| PALLD | palladin, cytoskeletal associated protein | -0.0204374 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0204229 |
| TUBA1B | tubulin, alpha 1b | -0.0202548 |
| TPM1 | tropomyosin 1 (alpha) | -0.0201728 |
| POSTN | periostin, osteoblast specific factor | -0.0201517 |
| CCND1 | cyclin D1 | -0.0200797 |
| PXDN | peroxidasin | -0.0199337 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0199291 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0196691 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0196467 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0192267 |
| RRBP1 | ribosome binding protein 1 | -0.0191992 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0191082 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0189948 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0187944 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0183247 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | -0.0179153 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0178843 |
| DUSP6 | dual specificity phosphatase 6 | -0.0175571 |
| RPLP0 | ribosomal protein, large, P0 | -0.01744 |
| MYO10 | myosin X | -0.0174277 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0173495 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0172743 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0172144 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0172036 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0170962 |
| THY1 | Thy-1 cell surface antigen | -0.0170536 |
| CNTN5 | contactin 5 | -0.0170363 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0169242 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0168292 |
| SDC2 | syndecan 2 | -0.0166154 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0166021 |
| CLIC4 | chloride intracellular channel 4 | -0.016546 |
