| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.42598 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.165237 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.110738 |
| FN1 | fibronectin 1 | 0.0997959 |
| ATXN1 | ataxin 1 | 0.0830996 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0818023 |
| ASPH | aspartate beta-hydroxylase | 0.0697744 |
| EHBP1 | EH domain binding protein 1 | 0.0694271 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0680589 |
| FMNL2 | formin-like 2 | 0.0666434 |
| FRMD5 | FERM domain containing 5 | 0.0628948 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0593169 |
| PEG3 | paternally expressed 3 | 0.0576747 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0570436 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0558053 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0552492 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0539216 |
| DST | dystonin | 0.0501358 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0483047 |
| RNF213 | ring finger protein 213 | 0.0481259 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0480388 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0472723 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0466388 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0439889 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.042711 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0402625 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0392657 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0392286 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0377491 |
| INTS6 | integrator complex subunit 6 | 0.0375994 |
| RUNX1 | runt-related transcription factor 1 | 0.0373124 |
| PLIN2 | perilipin 2 | 0.0356034 |
| ATP10A | ATPase, class V, type 10A | 0.0350095 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0347418 |
| TNS1 | tensin 1 | 0.0344856 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0337644 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0332947 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0330468 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0326954 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0326572 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0326323 |
| DSPP | dentin sialophosphoprotein | 0.0324093 |
| CP | ceruloplasmin (ferroxidase) | 0.0319284 |
| GK | glycerol kinase | 0.0316358 |
| H1-0 | H1.0 linker histone | 0.0304769 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0301487 |
| FAT1 | FAT atypical cadherin 1 | 0.0296621 |
| AHNAK | AHNAK nucleoprotein | 0.0294923 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.029402 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0289577 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0287466 |
| SMAD3 | SMAD family member 3 | 0.0287332 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0275898 |
| MSI2 | musashi RNA-binding protein 2 | 0.027474 |
| FAM107B | family with sequence similarity 107, member B | 0.0270121 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0265872 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0258679 |
| KIAA1217 | KIAA1217 | 0.0258523 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0258356 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0257977 |
| HDAC4 | histone deacetylase 4 | 0.0256992 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0256306 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0254751 |
| GPC6 | glypican 6 | 0.0252697 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0249371 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0247128 |
| NHSL1 | NHS-like 1 | 0.0238593 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0235267 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0233828 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0225618 |
| PRKCA | protein kinase C, alpha | 0.0220323 |
| PLEC | plectin | 0.0217644 |
| DISC1 | disrupted in schizophrenia 1 | 0.0217543 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0216331 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0216027 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0208303 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.020801 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0206192 |
| SEPTIN9 | septin 9 | 0.0204048 |
| ENO1 | enolase 1, (alpha) | 0.020354 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.020275 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0201334 |
| SBF2 | SET binding factor 2 | 0.0197732 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0197469 |
| RAD51B | RAD51 paralog B | 0.0197318 |
| MCL1 | myeloid cell leukemia 1 | 0.0195824 |
| HPCAL1 | hippocalcin-like 1 | 0.019468 |
| CMIP | c-Maf inducing protein | 0.019182 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0191688 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0190001 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | 0.0188594 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0187592 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0185796 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0185788 |
| FLNB | filamin B, beta | 0.0185263 |
| STK17A | serine/threonine kinase 17a | 0.0185042 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.018287 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0181606 |
| PLXDC2 | plexin domain containing 2 | 0.0178222 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0177141 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.339519 |
| APOB | apolipoprotein B | -0.203105 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.137857 |
| MT2A | metallothionein 2A | -0.11806 |
| C3 | complement component 3 | -0.108249 |
| RPS12 | ribosomal protein S12 | -0.0862885 |
| RPS6 | ribosomal protein S6 | -0.0712522 |
| RPL11 | ribosomal protein L11 | -0.0679689 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0676281 |
| RPL37A | ribosomal protein L37a | -0.0588392 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0566381 |
| RBM39 | RNA binding motif protein 39 | -0.0530549 |
| TRIM26 | tripartite motif containing 26 | -0.0524994 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0506655 |
| RPS8 | ribosomal protein S8 | -0.0484887 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0453311 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0451583 |
| RPL26 | ribosomal protein L26 | -0.0449911 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439241 |
| RPL9 | ribosomal protein L9 | -0.042109 |
| RPS3 | ribosomal protein S3 | -0.0412368 |
| GPC3 | glypican 3 | -0.0384948 |
| RPL31 | ribosomal protein L31 | -0.0373855 |
| MRTFA | myocardin related transcription factor A | -0.036807 |
| CFB | complement factor B | -0.0359916 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0359632 |
| CPE | carboxypeptidase E | -0.0350152 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.034648 |
| ITGAV | integrin, alpha V | -0.0336995 |
| RPS13 | ribosomal protein S13 | -0.0335422 |
| RPS19 | ribosomal protein S19 | -0.0334767 |
| PTMA | prothymosin, alpha | -0.0333913 |
| RPS2 | ribosomal protein S2 | -0.0324866 |
| A2M | alpha-2-macroglobulin | -0.0318999 |
| TF | transferrin | -0.0315575 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0310653 |
| RPS17 | ribosomal protein S17 | -0.0310111 |
| RPL7 | ribosomal protein L7 | -0.0298246 |
| RBM25 | RNA binding motif protein 25 | -0.0297675 |
| RPL10A | ribosomal protein L10a | -0.0292354 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0287452 |
| RPL5 | ribosomal protein L5 | -0.0275414 |
| GOLGA4 | golgin A4 | -0.027487 |
| RPLP2 | ribosomal protein, large, P2 | -0.0274221 |
| JMJD1C | jumonji domain containing 1C | -0.027318 |
| PRRC2C | proline-rich coiled-coil 2C | -0.02727 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0270539 |
| RPS21 | ribosomal protein S21 | -0.0269953 |
| RPL23 | ribosomal protein L23 | -0.0269372 |
| RPS24 | ribosomal protein S24 | -0.0267597 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0260568 |
| RRBP1 | ribosome binding protein 1 | -0.0260425 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0259021 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0258173 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0257908 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0252663 |
| RPL34 | ribosomal protein L34 | -0.0249593 |
| RPS27A | ribosomal protein S27a | -0.0247319 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0245421 |
| RPL36 | ribosomal protein L36 | -0.0242977 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0240882 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0240628 |
| MED13L | mediator complex subunit 13-like | -0.0240169 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0239226 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.023885 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0238563 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0236346 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0236187 |
| IFNGR1 | interferon gamma receptor 1 | -0.0234901 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0230883 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0230145 |
| UBXN4 | UBX domain protein 4 | -0.022871 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | -0.0225387 |
| RPS25 | ribosomal protein S25 | -0.0224701 |
| SET | SET nuclear proto-oncogene | -0.0224211 |
| RPL30 | ribosomal protein L30 | -0.0223448 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.022267 |
| H3-3B | H3.3 histone B | -0.0222101 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.022204 |
| SDC4 | syndecan 4 | -0.0219892 |
| RPLP1 | ribosomal protein, large, P1 | -0.0217981 |
| JAK1 | Janus kinase 1 | -0.0217172 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0215015 |
| RPL38 | ribosomal protein L38 | -0.0213893 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0211274 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0210953 |
| FTL | ferritin, light polypeptide | -0.0209015 |
| PAPOLA | poly(A) polymerase alpha | -0.0208738 |
| RPL19 | ribosomal protein L19 | -0.0205629 |
| RACK1 | receptor for activated C kinase 1 | -0.0204199 |
| B2M | beta-2-microglobulin | -0.0203628 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0201982 |
| RPS5 | ribosomal protein S5 | -0.0198762 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0196457 |
| TMSB10 | thymosin beta 10 | -0.0196349 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0195504 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0194 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0193781 |
| LCN2 | lipocalin 2 | -0.0191653 |
| WDR43 | WD repeat domain 43 | -0.0191058 |
