| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Adenine_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.13527 |
| FAT1 | FAT atypical cadherin 1 | 0.132493 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.131733 |
| KRT8 | keratin 8, type II | 0.120151 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.103294 |
| LDHA | lactate dehydrogenase A | 0.0989754 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0958896 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0866279 |
| LMO7 | LIM domain 7 | 0.0713592 |
| KRT18 | keratin 18, type I | 0.0666124 |
| EREG | epiregulin | 0.0631631 |
| ANXA2 | annexin A2 | 0.0584977 |
| ASPH | aspartate beta-hydroxylase | 0.0578232 |
| H1-0 | H1.0 linker histone | 0.0572777 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0536164 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0508356 |
| NDRG1 | N-myc downstream regulated 1 | 0.0471966 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.045915 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0426648 |
| PLEC | plectin | 0.0408575 |
| ONECUT3 | one cut homeobox 3 | 0.0403369 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0386415 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0378454 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0377109 |
| PRELID2 | PRELI domain containing 2 | 0.0350753 |
| CALR | calreticulin | 0.0334454 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0333383 |
| FTL | ferritin, light polypeptide | 0.0328794 |
| POTEF | POTE ankyrin domain family, member F | 0.0328417 |
| CLTC | clathrin, heavy chain (Hc) | 0.0324194 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0321243 |
| DSPP | dentin sialophosphoprotein | 0.0313415 |
| ACTG1 | actin gamma 1 | 0.0309526 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0308553 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.030627 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0302721 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0294784 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0280872 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0278734 |
| PKM | pyruvate kinase, muscle | 0.0269861 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0266826 |
| ENO1 | enolase 1, (alpha) | 0.026578 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.026406 |
| UBC | ubiquitin C | 0.0263955 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0261929 |
| CD164 | CD164 molecule, sialomucin | 0.026066 |
| PDZD8 | PDZ domain containing 8 | 0.0252109 |
| CAB39 | calcium binding protein 39 | 0.0252071 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0251748 |
| APP | amyloid beta (A4) precursor protein | 0.0250749 |
| PGK1 | phosphoglycerate kinase 1 | 0.0248896 |
| MYO5B | myosin VB | 0.0248522 |
| LAMB3 | laminin, beta 3 | 0.0242039 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.023958 |
| OGA | O-GlcNAcase | 0.0236132 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.023021 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0228925 |
| FAM13A | family with sequence similarity 13, member A | 0.0228861 |
| GLCE | glucuronic acid epimerase | 0.022796 |
| TPM3 | tropomyosin 3 | 0.0227831 |
| GRB10 | growth factor receptor-bound protein 10 | 0.022264 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0219675 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0219163 |
| AHNAK | AHNAK nucleoprotein | 0.0219059 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0216405 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0215284 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0213799 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0213739 |
| JAG1 | jagged 1 | 0.0213141 |
| NEBL | nebulette | 0.0211894 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0211464 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0210379 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0210276 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0210148 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0208943 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0208639 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0207324 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0205343 |
| PRSS3 | protease, serine, 3 | 0.0204856 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.020412 |
| TMSB4X | thymosin beta 4, X-linked | 0.0203809 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0201455 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0200897 |
| MUC13 | mucin 13, cell surface associated | 0.020083 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0199534 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0198282 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0196382 |
| TMEM45B | transmembrane protein 45B | 0.0194536 |
| SPAG9 | sperm associated antigen 9 | 0.0192319 |
| HDLBP | high density lipoprotein binding protein | 0.0190539 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0188382 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0186136 |
| AXIN2 | axin 2 | 0.018598 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0185096 |
| ARFGEF3 | ARFGEF family member 3 | 0.0185062 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0184926 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0184805 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0183404 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0181815 |
| TPM4 | tropomyosin 4 | 0.0181084 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.296184 |
| NPSR1 | neuropeptide S receptor 1 | -0.224679 |
| RPS6 | ribosomal protein S6 | -0.154073 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.139856 |
| PTMA | prothymosin, alpha | -0.108975 |
| GPHN | gephyrin | -0.105592 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.10518 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0832414 |
| RPS19 | ribosomal protein S19 | -0.0706375 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0612934 |
| RPLP1 | ribosomal protein, large, P1 | -0.0611917 |
| RPL34 | ribosomal protein L34 | -0.0588874 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0573282 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0534748 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0498664 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0495257 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0476815 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0468663 |
| RPS21 | ribosomal protein S21 | -0.0466938 |
| HMGA1 | high mobility group AT-hook 1 | -0.0466559 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0436324 |
| RPLP2 | ribosomal protein, large, P2 | -0.0430339 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0427917 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0427895 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0420843 |
| RPL36 | ribosomal protein L36 | -0.0420189 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0417658 |
| RPL35A | ribosomal protein L35a | -0.0396961 |
| RPL23 | ribosomal protein L23 | -0.0395373 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0393533 |
| RPL5 | ribosomal protein L5 | -0.0391479 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0386164 |
| RPL18 | ribosomal protein L18 | -0.0375984 |
| CALB1 | calbindin 1, 28kDa | -0.0371678 |
| PFN1 | profilin 1 | -0.0368339 |
| RPL8 | ribosomal protein L8 | -0.0366664 |
| S100A6 | S100 calcium binding protein A6 | -0.0364214 |
| PIGR | polymeric immunoglobulin receptor | -0.0363992 |
| CBX3 | chromobox homolog 3 | -0.0361361 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0358273 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0345084 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0335183 |
| MECOM | MDS1 and EVI1 complex locus | -0.0332436 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0331243 |
| RPS8 | ribosomal protein S8 | -0.0328662 |
| RPL37A | ribosomal protein L37a | -0.0322873 |
| INSIG1 | insulin induced gene 1 | -0.0322627 |
| RPS14 | ribosomal protein S14 | -0.0320491 |
| RBM25 | RNA binding motif protein 25 | -0.0320472 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0319708 |
| RPL12 | ribosomal protein L12 | -0.0318402 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0318044 |
| RPL32 | ribosomal protein L32 | -0.03175 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0310978 |
| TFF1 | trefoil factor 1 | -0.0309875 |
| RPS25 | ribosomal protein S25 | -0.0309789 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0306049 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0305199 |
| LSAMP | limbic system-associated membrane protein | -0.0303787 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0299676 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.029603 |
| PTEN | phosphatase and tensin homolog | -0.0295744 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0293863 |
| RPL27A | ribosomal protein L27a | -0.0290788 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0288549 |
| FHIT | fragile histidine triad | -0.0286431 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0278898 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0277579 |
| ASTN2 | astrotactin 2 | -0.0277238 |
| RPL9 | ribosomal protein L9 | -0.0274039 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0273463 |
| RPS27A | ribosomal protein S27a | -0.0257725 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0257497 |
| HMGB1 | high mobility group box 1 | -0.0255022 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.025354 |
| RNF217 | ring finger protein 217 | -0.0249675 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | -0.0248761 |
| BPTF | bromodomain PHD finger transcription factor | -0.024861 |
| S100A14 | S100 calcium binding protein A14 | -0.0245911 |
| S100A9 | S100 calcium binding protein A9 | -0.024261 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0240277 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0240086 |
| RPS29 | ribosomal protein S29 | -0.0238619 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0238404 |
| TPM1 | tropomyosin 1 (alpha) | -0.0231666 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0229365 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0229059 |
| RPS16 | ribosomal protein S16 | -0.022704 |
| PCBP2 | poly(rC) binding protein 2 | -0.0224268 |
| VCL | vinculin | -0.0223956 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0221943 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0220487 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0218249 |
| RPL21 | ribosomal protein L21 | -0.0217772 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0213987 |
| RPL26 | ribosomal protein L26 | -0.0213554 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0212801 |
| RPL36A | ribosomal protein L36a | -0.0210853 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0209762 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0206956 |