| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.137045 |
| POTEF | POTE ankyrin domain family, member F | 0.122786 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.118189 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0836539 |
| CD44 | CD44 molecule (Indian blood group) | 0.0713106 |
| CAPRIN2 | caprin family member 2 | 0.0711384 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0689386 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0656735 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0610201 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0609849 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0602274 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0555703 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0543546 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0531199 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0524804 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0523808 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0519366 |
| EZR | ezrin | 0.049612 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0463421 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0455217 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0451375 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0434255 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0425532 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0415795 |
| ANGPTL4 | angiopoietin-like 4 | 0.04114 |
| PODXL | podocalyxin-like | 0.0411302 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0406895 |
| JUN | jun proto-oncogene | 0.0405872 |
| DST | dystonin | 0.0397974 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0389159 |
| VEGFA | vascular endothelial growth factor A | 0.0381374 |
| RUNX1 | runt-related transcription factor 1 | 0.0378219 |
| EGR1 | early growth response 1 | 0.0366975 |
| TPM4 | tropomyosin 4 | 0.0358773 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0349644 |
| RPS8 | ribosomal protein S8 | 0.0347113 |
| SEC24A | SEC24 family member A | 0.0341796 |
| B2M | beta-2-microglobulin | 0.033935 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0332037 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.032702 |
| TXNIP | thioredoxin interacting protein | 0.0323052 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.030662 |
| PCDH1 | protocadherin 1 | 0.0306377 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0304924 |
| NAV2 | neuron navigator 2 | 0.0302404 |
| RPS6 | ribosomal protein S6 | 0.0297144 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0296482 |
| RPS12 | ribosomal protein S12 | 0.0294777 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0293411 |
| HMGA1 | high mobility group AT-hook 1 | 0.0289563 |
| HLA-B | major histocompatibility complex, class I, B | 0.0289546 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0289136 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0287609 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0284437 |
| RPL37 | ribosomal protein L37 | 0.0283895 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0282201 |
| UPP1 | uridine phosphorylase 1 | 0.028083 |
| LOXL2 | lysyl oxidase-like 2 | 0.0278837 |
| RPL37A | ribosomal protein L37a | 0.0277127 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0274412 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0271651 |
| HLA-E | major histocompatibility complex, class I, E | 0.0264647 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0263281 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0263257 |
| FMNL2 | formin-like 2 | 0.0263141 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.025398 |
| SLK | STE20-like kinase | 0.0252954 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0252728 |
| SEPTIN9 | septin 9 | 0.0243174 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0242781 |
| CALR | calreticulin | 0.0242504 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0241543 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0239821 |
| EREG | epiregulin | 0.0238613 |
| PDE10A | phosphodiesterase 10A | 0.0238499 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0238491 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0236933 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0236349 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.023384 |
| EMP1 | epithelial membrane protein 1 | 0.0233699 |
| TP53BP2 | tumor protein p53 binding protein 2 | 0.0232952 |
| ANXA2 | annexin A2 | 0.0232683 |
| NAV1 | neuron navigator 1 | 0.0232216 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0232209 |
| VEGFC | vascular endothelial growth factor C | 0.023011 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0228257 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0227794 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0226936 |
| TXNRD1 | thioredoxin reductase 1 | 0.02232 |
| PLK2 | polo-like kinase 2 | 0.0220582 |
| PLIN2 | perilipin 2 | 0.0219856 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0219132 |
| TGM2 | transglutaminase 2 | 0.0217892 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0217793 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0217713 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0216778 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0215497 |
| TPM3 | tropomyosin 3 | 0.021379 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0213456 |
| CEP250 | centrosomal protein 250kDa | 0.0211711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122071 |
| MT2A | metallothionein 2A | -0.0997321 |
| RAD51B | RAD51 paralog B | -0.0781652 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0749663 |
| TMSB10 | thymosin beta 10 | -0.0748027 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0647708 |
| PTMA | prothymosin, alpha | -0.0528027 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0497861 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0488684 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0487919 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0463235 |
| PRELID2 | PRELI domain containing 2 | -0.0462996 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0453616 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0449557 |
| SPAG9 | sperm associated antigen 9 | -0.0441158 |
| RBM39 | RNA binding motif protein 39 | -0.0440638 |
| NF1 | neurofibromin 1 | -0.0427687 |
| SBF2 | SET binding factor 2 | -0.0418391 |
| TP63 | tumor protein p63 | -0.0416597 |
| RBM25 | RNA binding motif protein 25 | -0.0404667 |
| NEK10 | NIMA-related kinase 10 | -0.039734 |
| EXOC4 | exocyst complex component 4 | -0.0388218 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0387532 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0385509 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0379056 |
| DIAPH3 | diaphanous-related formin 3 | -0.0370376 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0357753 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0352531 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0344943 |
| MT1X | metallothionein 1X | -0.034379 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0337487 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0336294 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0327372 |
| DPH6 | diphthamine biosynthesis 6 | -0.0326194 |
| ANLN | anillin, actin binding protein | -0.0324327 |
| CENPF | centromere protein F, 350/400kDa | -0.0322789 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0320683 |
| ZNF292 | zinc finger protein 292 | -0.0314325 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0308042 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0293365 |
| TMSB4X | thymosin beta 4, X-linked | -0.0286779 |
| CEP128 | centrosomal protein 128kDa | -0.0284744 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0284338 |
| GNAS | GNAS complex locus | -0.0283662 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.028178 |
| USP34 | ubiquitin specific peptidase 34 | -0.0279444 |
| ECT2 | epithelial cell transforming 2 | -0.0266635 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0265996 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0264359 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0262167 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0256918 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0256657 |
| TOP1 | topoisomerase (DNA) I | -0.0255936 |
| NCOR1 | nuclear receptor corepressor 1 | -0.024986 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0246515 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0245048 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0244387 |
| RCOR1 | REST corepressor 1 | -0.0242234 |
| KLF6 | Kruppel-like factor 6 | -0.0241848 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0241191 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0239331 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0236531 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0234695 |
| FHIT | fragile histidine triad | -0.0233238 |
| COMMD10 | COMM domain containing 10 | -0.0232357 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0231488 |
| ETNK1 | ethanolamine kinase 1 | -0.0230994 |
| FNIP1 | folliculin interacting protein 1 | -0.0229991 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0228039 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0227592 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0225599 |
| FUS | FUS RNA binding protein | -0.0225403 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0225187 |
| CFDP1 | craniofacial development protein 1 | -0.0220004 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0219771 |
| SCFD1 | sec1 family domain containing 1 | -0.0217538 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0217505 |
| SRPK2 | SRSF protein kinase 2 | -0.0215671 |
| KIAA1958 | KIAA1958 | -0.0215633 |
| SMAD2 | SMAD family member 2 | -0.0213632 |
| SRGN | serglycin | -0.0213373 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0212936 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.02116 |
| OGA | O-GlcNAcase | -0.0211324 |
| PHIP | pleckstrin homology domain interacting protein | -0.0211293 |
| ZNF217 | zinc finger protein 217 | -0.0210212 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | -0.0208779 |
| ABI2 | abl-interactor 2 | -0.0208279 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0207912 |
| MKI67 | marker of proliferation Ki-67 | -0.0207492 |
| MORF4L2 | mortality factor 4 like 2 | -0.0207327 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0207133 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0206841 |
| HMGB2 | high mobility group box 2 | -0.020673 |
| RRM2 | ribonucleotide reductase M2 | -0.0206615 |
| RTTN | rotatin | -0.0206149 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0205618 |
| OLA1 | Obg-like ATPase 1 | -0.0203106 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0202819 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0202186 |
