| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.143171 |
| GRAMD1B | GRAM domain containing 1B | 0.102819 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0976884 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0872556 |
| MCL1 | myeloid cell leukemia 1 | 0.0783073 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0733665 |
| INTS6 | integrator complex subunit 6 | 0.0731046 |
| SLTM | SAFB-like, transcription modulator | 0.0650808 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0625465 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0623822 |
| PM20D1 | peptidase M20 domain containing 1 | 0.062257 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0609302 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0589384 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0566436 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0554543 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.055378 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0552885 |
| PLEC | plectin | 0.0551652 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0548542 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0543127 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0536303 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0480362 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0446949 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0441524 |
| LAMA4 | laminin, alpha 4 | 0.0428487 |
| CES1 | carboxylesterase 1 | 0.0423124 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0409364 |
| POTEF | POTE ankyrin domain family, member F | 0.0408368 |
| FAM13A | family with sequence similarity 13, member A | 0.0396157 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0394201 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0392072 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0389909 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0373176 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.036679 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0348892 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0333211 |
| MSN | moesin | 0.0332796 |
| ATP11A | ATPase, class VI, type 11A | 0.0330441 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0330404 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0325884 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0324576 |
| HOMER1 | homer scaffolding protein 1 | 0.0319421 |
| SMAD3 | SMAD family member 3 | 0.0312365 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0306251 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0303686 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0303207 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0298641 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0297489 |
| BMP6 | bone morphogenetic protein 6 | 0.0295528 |
| SIK3 | SIK family kinase 3 | 0.0294838 |
| SCEL | sciellin | 0.0292131 |
| SPAG9 | sperm associated antigen 9 | 0.0287378 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.028445 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0279997 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0278305 |
| PDE8A | phosphodiesterase 8A | 0.0273607 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0272654 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0271548 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0268535 |
| HELZ | helicase with zinc finger | 0.0267387 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0261083 |
| RNF145 | ring finger protein 145 | 0.0255395 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0254438 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0252719 |
| VEGFC | vascular endothelial growth factor C | 0.0252244 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0249567 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0246031 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0242965 |
| MAP7 | microtubule-associated protein 7 | 0.0242304 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0238682 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0238295 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0236599 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0236362 |
| WDR1 | WD repeat domain 1 | 0.0235568 |
| CTBP2 | C-terminal binding protein 2 | 0.0235263 |
| RNF213 | ring finger protein 213 | 0.0231238 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0230637 |
| CMIP | c-Maf inducing protein | 0.0229641 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0228004 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0227029 |
| HDAC4 | histone deacetylase 4 | 0.0226251 |
| CSNK1E | casein kinase 1, epsilon | 0.0224376 |
| MYO1E | myosin IE | 0.0223031 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0221337 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0219997 |
| ANXA1 | annexin A1 | 0.0219994 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0218668 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0218167 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0214288 |
| CD163L1 | CD163 molecule-like 1 | 0.0212261 |
| BRD2 | bromodomain containing 2 | 0.0211939 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0209368 |
| PYGL | phosphorylase, glycogen, liver | 0.0208503 |
| NABP1 | nucleic acid binding protein 1 | 0.0207762 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0206696 |
| SMYD3 | SET and MYND domain containing 3 | 0.0206657 |
| WASF2 | WAS protein family, member 2 | 0.0205026 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0204491 |
| NPTN | neuroplastin | 0.02002 |
| ACTN1 | actinin, alpha 1 | 0.0199592 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.201412 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.13687 |
| TMSB10 | thymosin beta 10 | -0.104505 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0878007 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0786458 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0736655 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0730112 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0724564 |
| ASPH | aspartate beta-hydroxylase | -0.0697016 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0669293 |
| MT2A | metallothionein 2A | -0.0655768 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.063168 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0613045 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0597727 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0535699 |
| RPS3 | ribosomal protein S3 | -0.0506191 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0460976 |
| LAMC2 | laminin, gamma 2 | -0.045822 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.044941 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0429038 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0419021 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0416866 |
| RPL34 | ribosomal protein L34 | -0.0412532 |
| S100A10 | S100 calcium binding protein A10 | -0.0396224 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0390915 |
| CST3 | cystatin C | -0.0372633 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0370406 |
| HLA-B | major histocompatibility complex, class I, B | -0.035906 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0354628 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.035113 |
| RPL35A | ribosomal protein L35a | -0.034847 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0342651 |
| RPL37A | ribosomal protein L37a | -0.0337369 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0334515 |
| RPS24 | ribosomal protein S24 | -0.0329568 |
| RPS6 | ribosomal protein S6 | -0.0326091 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0323783 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0323029 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.032075 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0317355 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0317101 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.031627 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0310644 |
| USP34 | ubiquitin specific peptidase 34 | -0.0309659 |
| CCND1 | cyclin D1 | -0.0308267 |
| MKI67 | marker of proliferation Ki-67 | -0.0304046 |
| RBM39 | RNA binding motif protein 39 | -0.0300822 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0297292 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0296519 |
| TRIM56 | tripartite motif containing 56 | -0.0293697 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0289315 |
| RPS25 | ribosomal protein S25 | -0.0286416 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0284395 |
| S100A11 | S100 calcium binding protein A11 | -0.028394 |
| RAB27B | RAB27B, member RAS oncogene family | -0.028273 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0281456 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0281002 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0267116 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0266278 |
| RPS27A | ribosomal protein S27a | -0.0261133 |
| RPL11 | ribosomal protein L11 | -0.0261043 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0259064 |
| HM13 | histocompatibility (minor) 13 | -0.0255581 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0255529 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0254273 |
| GNAS | GNAS complex locus | -0.0253565 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.025314 |
| PGK1 | phosphoglycerate kinase 1 | -0.024963 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0248934 |
| RPS2 | ribosomal protein S2 | -0.0244234 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0239965 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0237914 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0237638 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0237434 |
| GOLGA4 | golgin A4 | -0.0236836 |
| KRT7 | keratin 7, type II | -0.02368 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0236692 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.023631 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.023268 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0232098 |
| S100A9 | S100 calcium binding protein A9 | -0.0232042 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0231852 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0230869 |
| GOLGB1 | golgin B1 | -0.0230041 |
| RPS8 | ribosomal protein S8 | -0.0229515 |
| RPL31 | ribosomal protein L31 | -0.0227606 |
| RPL26 | ribosomal protein L26 | -0.0226861 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0225468 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0224942 |
| RPL12 | ribosomal protein L12 | -0.0223918 |
| ANKRD10 | ankyrin repeat domain 10 | -0.022353 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0222671 |
| RPL9 | ribosomal protein L9 | -0.0219798 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0219642 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0219228 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.021837 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0217452 |
| TNPO1 | transportin 1 | -0.0216494 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0214935 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0214218 |
