| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.125019 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0903622 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0820737 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0719809 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0700739 |
| CD44 | CD44 molecule (Indian blood group) | 0.0682516 |
| TGM2 | transglutaminase 2 | 0.0668754 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.064886 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0609239 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0596241 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0571419 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0517097 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0511648 |
| NAV2 | neuron navigator 2 | 0.0476028 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0463654 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0462719 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0446183 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.041478 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0409942 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0403941 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0401239 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0396815 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0391726 |
| VEGFA | vascular endothelial growth factor A | 0.0375778 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.036883 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.036466 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0361933 |
| LOXL2 | lysyl oxidase-like 2 | 0.0346028 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0343963 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0342025 |
| FLNB | filamin B, beta | 0.0330044 |
| PCBP2 | poly(rC) binding protein 2 | 0.0329347 |
| CANX | calnexin | 0.0327584 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0326701 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0324671 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0323242 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0323204 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0319354 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0317848 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314786 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0309004 |
| ENO1 | enolase 1, (alpha) | 0.0304715 |
| SEPTIN9 | septin 9 | 0.0304657 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0302183 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0298227 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0295527 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0288394 |
| SYAP1 | synapse associated protein 1 | 0.0285629 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0281714 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0281456 |
| MEIS1 | Meis homeobox 1 | 0.0280431 |
| TOP1 | topoisomerase (DNA) I | 0.0270112 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0269483 |
| RHCG | Rh family, C glycoprotein | 0.0266634 |
| ADD3 | adducin 3 (gamma) | 0.0266575 |
| STK38L | serine/threonine kinase 38 like | 0.0262168 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0261612 |
| ATXN1 | ataxin 1 | 0.0259192 |
| ANGPTL4 | angiopoietin-like 4 | 0.0251556 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0250298 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248553 |
| XPO1 | exportin 1 | 0.0241891 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0239215 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0239103 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0238215 |
| KSR1 | kinase suppressor of ras 1 | 0.0238009 |
| HMGA2 | high mobility group AT-hook 2 | 0.0234916 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.023438 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.023353 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0232849 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0229297 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0227494 |
| ECE1 | endothelin converting enzyme 1 | 0.022533 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0220792 |
| MYO10 | myosin X | 0.0219773 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0219195 |
| MSN | moesin | 0.0219025 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0217981 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0216889 |
| FAM107B | family with sequence similarity 107, member B | 0.0216752 |
| VMP1 | vacuole membrane protein 1 | 0.0216456 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0211047 |
| SFTPA2 | surfactant protein A2 | 0.0210436 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0210116 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0209604 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0209145 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0208896 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0205782 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.020525 |
| KYNU | kynureninase | 0.0205237 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0205153 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0205039 |
| FANCL | Fanconi anemia, complementation group L | 0.0204949 |
| PFKP | phosphofructokinase, platelet | 0.0203772 |
| HELZ | helicase with zinc finger | 0.0203411 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0201422 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0199836 |
| POTEF | POTE ankyrin domain family, member F | 0.0198644 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.019834 |
| ANXA2 | annexin A2 | 0.0197372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.202715 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.178492 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.12538 |
| CDH13 | cadherin 13 | -0.118095 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0969993 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0884678 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.084008 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0811426 |
| NRG1 | neuregulin 1 | -0.0783459 |
| FN1 | fibronectin 1 | -0.0749764 |
| GPC6 | glypican 6 | -0.0748044 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0745542 |
| TMSB10 | thymosin beta 10 | -0.0723756 |
| MTSS1 | metastasis suppressor 1 | -0.0629055 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0562833 |
| STC1 | stanniocalcin 1 | -0.0546431 |
| MEF2A | myocyte enhancer factor 2A | -0.0533551 |
| GLCCI1 | glucocorticoid induced 1 | -0.0529078 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0480903 |
| USP34 | ubiquitin specific peptidase 34 | -0.0471315 |
| RAI14 | retinoic acid induced 14 | -0.0465353 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0453285 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0451569 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0437843 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0409796 |
| ZNF804A | zinc finger protein 804A | -0.0403213 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0388471 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0382574 |
| CFAP20DC | CFAP20 domain containing | -0.0377516 |
| CDK14 | cyclin-dependent kinase 14 | -0.0375757 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0364429 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0364254 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0358891 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0357924 |
| IL1B | interleukin 1, beta | -0.035786 |
| DIAPH2 | diaphanous-related formin 2 | -0.0352918 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.034877 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0348573 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0343108 |
| PRRX1 | paired related homeobox 1 | -0.0335668 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.033292 |
| DTNA | dystrobrevin, alpha | -0.0324724 |
| CUX1 | cut-like homeobox 1 | -0.0322419 |
| OSMR | oncostatin M receptor | -0.0316835 |
| NLK | nemo-like kinase | -0.0311265 |
| CLMP | CXADR-like membrane protein | -0.0309765 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0303177 |
| CCDC91 | coiled-coil domain containing 91 | -0.0296889 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0296056 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0287623 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0287576 |
| OXR1 | oxidation resistance 1 | -0.0280673 |
| TMEM165 | transmembrane protein 165 | -0.0278754 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0276545 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0275344 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0275329 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0274118 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0270489 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0268835 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0265166 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0264952 |
| SYT1 | synaptotagmin I | -0.0261603 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0259364 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0259119 |
| MECOM | MDS1 and EVI1 complex locus | -0.0256267 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0250993 |
| CMIP | c-Maf inducing protein | -0.0250382 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0249877 |
| PYGL | phosphorylase, glycogen, liver | -0.0248226 |
| NAV3 | neuron navigator 3 | -0.023987 |
| NUMB | numb homolog (Drosophila) | -0.0239711 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0238969 |
| PRSS23 | protease, serine, 23 | -0.0236433 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0235892 |
| S100A6 | S100 calcium binding protein A6 | -0.0231759 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0227499 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0226363 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0224829 |
| ABCA9 | ATP-binding cassette, sub-family A (ABC1), member 9 | -0.0223202 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | -0.0222377 |
| RBM39 | RNA binding motif protein 39 | -0.0221092 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0221091 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0220425 |
| PRR16 | proline rich 16 | -0.0219129 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0218822 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0218776 |
| ENOSF1 | enolase superfamily member 1 | -0.0217085 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0216474 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.021362 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0212699 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0211992 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0211237 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0210529 |
| PLAT | plasminogen activator, tissue | -0.0210009 |
| THBD | thrombomodulin | -0.0207182 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0205749 |
| ATG7 | autophagy related 7 | -0.0204624 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0203842 |
| SNX9 | sorting nexin 9 | -0.0203588 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.02026 |
