| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.326326 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.157943 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.110903 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.106763 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0831564 |
| KYNU | kynureninase | 0.0705476 |
| CMIP | c-Maf inducing protein | 0.0696951 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0688843 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0660129 |
| WWOX | WW domain containing oxidoreductase | 0.0545155 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0532738 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0532601 |
| POTEF | POTE ankyrin domain family, member F | 0.0526533 |
| BRD2 | bromodomain containing 2 | 0.052329 |
| FAM107B | family with sequence similarity 107, member B | 0.0508657 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0435926 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0428919 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0422316 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0421195 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0399625 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0398372 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0375499 |
| PDE10A | phosphodiesterase 10A | 0.0375114 |
| FLNA | filamin A, alpha | 0.0375089 |
| MSN | moesin | 0.0365595 |
| LAMA5 | laminin, alpha 5 | 0.0365342 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.035682 |
| TPM3 | tropomyosin 3 | 0.035577 |
| INTS6 | integrator complex subunit 6 | 0.0353584 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0337962 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0336318 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0333738 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0330459 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0329269 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0328925 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0323824 |
| ASPH | aspartate beta-hydroxylase | 0.0317377 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0316453 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0313351 |
| ATXN1 | ataxin 1 | 0.0311932 |
| BMP6 | bone morphogenetic protein 6 | 0.0310588 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0309373 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.0304823 |
| NTN4 | netrin 4 | 0.030243 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0302036 |
| ATF6 | activating transcription factor 6 | 0.0299503 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0297435 |
| ACTN1 | actinin, alpha 1 | 0.0294676 |
| FHIT | fragile histidine triad | 0.0287036 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0286297 |
| PLEC | plectin | 0.0272829 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0272664 |
| PRELID2 | PRELI domain containing 2 | 0.0271724 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0270508 |
| COPA | coatomer protein complex, subunit alpha | 0.026478 |
| PSEN1 | presenilin 1 | 0.026333 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0260168 |
| WDR59 | WD repeat domain 59 | 0.0257184 |
| NNMT | nicotinamide N-methyltransferase | 0.0257166 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.024836 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0247471 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0242623 |
| TLN1 | talin 1 | 0.02392 |
| SEPTIN9 | septin 9 | 0.0238969 |
| SVIL | supervillin | 0.0237579 |
| EP300 | E1A binding protein p300 | 0.0233513 |
| AHR | aryl hydrocarbon receptor | 0.0231657 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0231519 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0229351 |
| RPL3 | ribosomal protein L3 | 0.0226173 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0223983 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0221559 |
| PLS3 | plastin 3 | 0.0214821 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0213042 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0212852 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0208176 |
| NRG1 | neuregulin 1 | 0.0207865 |
| YLPM1 | YLP motif containing 1 | 0.0207294 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0206661 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0206441 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0206043 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0205779 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0205418 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0203824 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0202095 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0201617 |
| MCL1 | myeloid cell leukemia 1 | 0.0199772 |
| UTRN | utrophin | 0.0199028 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0197495 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0197182 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0195989 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0195762 |
| FAT1 | FAT atypical cadherin 1 | 0.0193527 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0193226 |
| PCBP2 | poly(rC) binding protein 2 | 0.0191756 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.0190607 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.018943 |
| VEGFC | vascular endothelial growth factor C | 0.0188839 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.018852 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0188268 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.161493 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.155932 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.14584 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.136909 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0896609 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0754785 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0688124 |
| VIM | vimentin | -0.0607773 |
| TMSB10 | thymosin beta 10 | -0.0573247 |
| IER3 | immediate early response 3 | -0.0562922 |
| TXNRD1 | thioredoxin reductase 1 | -0.0560388 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0547374 |
| CAVIN1 | caveolae associated protein 1 | -0.0506772 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0469263 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0440632 |
| PTMA | prothymosin, alpha | -0.0436493 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0435819 |
| FTL | ferritin, light polypeptide | -0.0418726 |
| NAV3 | neuron navigator 3 | -0.0408437 |
| PYGL | phosphorylase, glycogen, liver | -0.0397435 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0384394 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0365566 |
| AK1 | adenylate kinase 1 | -0.0360158 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0333576 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0328299 |
| RPS21 | ribosomal protein S21 | -0.0327704 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0320464 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.030909 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0286201 |
| S100A6 | S100 calcium binding protein A6 | -0.0284225 |
| RPS27A | ribosomal protein S27a | -0.0283438 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0283254 |
| CANX | calnexin | -0.0270534 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0270319 |
| RPL36 | ribosomal protein L36 | -0.0263519 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0261823 |
| RPL23 | ribosomal protein L23 | -0.0258082 |
| SNX14 | sorting nexin 14 | -0.0255745 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0255622 |
| RPL31 | ribosomal protein L31 | -0.0253488 |
| S100A10 | S100 calcium binding protein A10 | -0.0253235 |
| AHNAK | AHNAK nucleoprotein | -0.0250771 |
| CFDP1 | craniofacial development protein 1 | -0.025042 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0248066 |
| RPS6 | ribosomal protein S6 | -0.0247306 |
| HDAC9 | histone deacetylase 9 | -0.0246558 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0245138 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0242854 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0240676 |
| RPS19 | ribosomal protein S19 | -0.0237024 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0236847 |
| GLG1 | golgi glycoprotein 1 | -0.0236263 |
| RBM39 | RNA binding motif protein 39 | -0.0235588 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0235412 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0232704 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0231534 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0230837 |
| SHTN1 | shootin 1 | -0.0228025 |
| ABI2 | abl-interactor 2 | -0.0225408 |
| RPL35A | ribosomal protein L35a | -0.0224947 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0224823 |
| APP | amyloid beta (A4) precursor protein | -0.0224734 |
| RPL37 | ribosomal protein L37 | -0.0218727 |
| RPS8 | ribosomal protein S8 | -0.0217668 |
| RPS27 | ribosomal protein S27 | -0.0215606 |
| RPS29 | ribosomal protein S29 | -0.0213922 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0213689 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0212976 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0211395 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0209991 |
| FLNB | filamin B, beta | -0.0208895 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0208264 |
| RGS20 | regulator of G-protein signaling 20 | -0.0207154 |
| NUMB | numb homolog (Drosophila) | -0.0204557 |
| IWS1 | IWS1 homolog (S. cerevisiae) | -0.0202349 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0201977 |
| NEMF | nuclear export mediator factor | -0.0201198 |
| RPLP0 | ribosomal protein, large, P0 | -0.0201114 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0200825 |
| NOP58 | NOP58 ribonucleoprotein | -0.0200252 |
| PFDN2 | prefoldin subunit 2 | -0.0199401 |
| GOLGA4 | golgin A4 | -0.0198892 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0195604 |
| MATR3 | matrin 3 | -0.0195334 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0194704 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0193772 |
| RPS25 | ribosomal protein S25 | -0.0193046 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0192781 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0191096 |
| SEPTIN10 | septin 10 | -0.0190028 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.018724 |
| RPL26 | ribosomal protein L26 | -0.0186608 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0186581 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0186022 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0184708 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0184565 |
| RPL4 | ribosomal protein L4 | -0.0183947 |
| TLK1 | tousled-like kinase 1 | -0.018252 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0182067 |
| RSF1 | remodeling and spacing factor 1 | -0.0180702 |
