| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.146486 |
| DSCAM | Down syndrome cell adhesion molecule | 0.104193 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0965336 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0902707 |
| RIGI | RNA sensor RIG-I | 0.0856081 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.084392 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0783394 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0772231 |
| KYNU | kynureninase | 0.0715246 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0714433 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0710577 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0663254 |
| ABHD17C | abhydrolase domain containing 17C | 0.0640452 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0618224 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0610406 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0600625 |
| DST | dystonin | 0.0574051 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0570166 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0566106 |
| EFNA5 | ephrin-A5 | 0.055208 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0551132 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0537466 |
| PGK1 | phosphoglycerate kinase 1 | 0.0534455 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0525165 |
| BBX | bobby sox homolog (Drosophila) | 0.0524104 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0523944 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0519844 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0516919 |
| EGFR | epidermal growth factor receptor | 0.0515471 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.050924 |
| GPC6 | glypican 6 | 0.050664 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0505365 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.050332 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0501717 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0490633 |
| DTNA | dystrobrevin, alpha | 0.0487296 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0477271 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0473751 |
| PTEN | phosphatase and tensin homolog | 0.0465561 |
| SMAD2 | SMAD family member 2 | 0.0463426 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0461419 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0458639 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0456607 |
| TXNIP | thioredoxin interacting protein | 0.044201 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0440088 |
| MYO5B | myosin VB | 0.0440044 |
| FAT1 | FAT atypical cadherin 1 | 0.0433659 |
| GSK3B | glycogen synthase kinase 3 beta | 0.043286 |
| ZNF292 | zinc finger protein 292 | 0.0432501 |
| SVIL | supervillin | 0.0432011 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.043141 |
| BPTF | bromodomain PHD finger transcription factor | 0.0421456 |
| H1-0 | H1.0 linker histone | 0.0411421 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0410011 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0406712 |
| JMJD1C | jumonji domain containing 1C | 0.0402681 |
| ACTN4 | actinin, alpha 4 | 0.0400694 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0399299 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0387139 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0385077 |
| NPTN | neuroplastin | 0.0382285 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0382149 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0380844 |
| BCL2L1 | BCL2-like 1 | 0.0380283 |
| NEK7 | NIMA-related kinase 7 | 0.0376864 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0373303 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.037144 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0370242 |
| ANXA11 | annexin A11 | 0.0368411 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0365939 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0363539 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0363139 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0360822 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0360702 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0358222 |
| ATXN1 | ataxin 1 | 0.035599 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0352062 |
| LAMA4 | laminin, alpha 4 | 0.0351112 |
| NDRG1 | N-myc downstream regulated 1 | 0.0349122 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0347562 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0347242 |
| YTHDC1 | YTH domain containing 1 | 0.0344863 |
| PRDM1 | PR domain containing 1, with ZNF domain | 0.0340243 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.033974 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0339552 |
| FN1 | fibronectin 1 | 0.0339192 |
| DICER1 | dicer 1, ribonuclease type III | 0.0338008 |
| VMP1 | vacuole membrane protein 1 | 0.0336068 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0332056 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0330394 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0328124 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.032421 |
| EXOC6B | exocyst complex component 6B | 0.0323379 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0322644 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.032258 |
| CDK6 | cyclin-dependent kinase 6 | 0.0321526 |
| TCF12 | transcription factor 12 | 0.0321295 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0320461 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.031678 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0316529 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.155564 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.121939 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0983234 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0937874 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0930629 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0712577 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0689964 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0660069 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0619771 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0609368 |
| TC2N | tandem C2 domains, nuclear | -0.0575328 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0569622 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0556196 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | -0.0518743 |
| HMGA2 | high mobility group AT-hook 2 | -0.0497065 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0494616 |
| RPLP1 | ribosomal protein, large, P1 | -0.049443 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.04903 |
| ANXA2 | annexin A2 | -0.0476648 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0474583 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0473361 |
| SGMS2 | sphingomyelin synthase 2 | -0.0443822 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0443063 |
| MT2A | metallothionein 2A | -0.0442911 |
| RBM47 | RNA binding motif protein 47 | -0.044042 |
| RPL37A | ribosomal protein L37a | -0.0434329 |
| TRIP11 | thyroid hormone receptor interactor 11 | -0.0434122 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0433424 |
| VCL | vinculin | -0.0421083 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0419561 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0414229 |
| RESF1 | retroelement silencing factor 1 | -0.0412494 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0411929 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0409013 |
| MMP1 | matrix metallopeptidase 1 | -0.0407929 |
| MEF2A | myocyte enhancer factor 2A | -0.040489 |
| OXR1 | oxidation resistance 1 | -0.0403711 |
| CMIP | c-Maf inducing protein | -0.0396325 |
| AFDN | afadin, adherens junction formation factor | -0.0387068 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0385696 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0385633 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0377471 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.036859 |
| RPS21 | ribosomal protein S21 | -0.036589 |
| RPS24 | ribosomal protein S24 | -0.0365196 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0363987 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0362329 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0362153 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0361463 |
| VGLL3 | vestigial-like family member 3 | -0.0361317 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0359705 |
| FBN1 | fibrillin 1 | -0.0356649 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0356643 |
| PAPOLA | poly(A) polymerase alpha | -0.0354677 |
| MAP4 | microtubule-associated protein 4 | -0.0354004 |
| CLDN4 | claudin 4 | -0.0351534 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0351456 |
| YME1L1 | YME1-like 1 ATPase | -0.0347919 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0346981 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0345349 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0344327 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0340772 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0340123 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0339213 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0336724 |
| TPCN1 | two pore segment channel 1 | -0.0335238 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.033473 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0331759 |
| ADM | adrenomedullin | -0.0330329 |
| RPS27A | ribosomal protein S27a | -0.0325607 |
| KRT17 | keratin 17, type I | -0.032557 |
| FTL | ferritin, light polypeptide | -0.0324241 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0322886 |
| S100A9 | S100 calcium binding protein A9 | -0.0321172 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0318506 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0317847 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0317397 |
| SNX14 | sorting nexin 14 | -0.031686 |
| RPL34 | ribosomal protein L34 | -0.0315152 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0313475 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0312715 |
| CD44 | CD44 molecule (Indian blood group) | -0.0310195 |
| RPL11 | ribosomal protein L11 | -0.0309773 |
| RBM10 | RNA binding motif protein 10 | -0.030775 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0307745 |
| HM13 | histocompatibility (minor) 13 | -0.030566 |
| IER3 | immediate early response 3 | -0.0303606 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0303121 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0302387 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0302189 |
| ACTG1 | actin gamma 1 | -0.0300294 |
| TJP2 | tight junction protein 2 | -0.0299862 |
| PALLD | palladin, cytoskeletal associated protein | -0.0298057 |
| OCLN | occludin | -0.0297452 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0297003 |
| FNBP1 | formin binding protein 1 | -0.0296308 |
| NRP1 | neuropilin 1 | -0.029189 |
| CNKSR3 | CNKSR family member 3 | -0.0291299 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0290731 |
| KRT18 | keratin 18, type I | -0.0290273 |
