| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.153976 |
| VEGFA | vascular endothelial growth factor A | 0.111724 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.104784 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0966507 |
| NDRG1 | N-myc downstream regulated 1 | 0.0946204 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0791281 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0763644 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0755155 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0600656 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0574273 |
| MSN | moesin | 0.0571896 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0563551 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0551378 |
| TPM3 | tropomyosin 3 | 0.0540507 |
| TMF1 | TATA element modulatory factor 1 | 0.0538695 |
| CALR | calreticulin | 0.0525973 |
| FN1 | fibronectin 1 | 0.0519904 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0498321 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0477896 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0464706 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0444752 |
| ACTG1 | actin gamma 1 | 0.0438561 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0429653 |
| PTK2 | protein tyrosine kinase 2 | 0.042066 |
| COPA | coatomer protein complex, subunit alpha | 0.0415072 |
| NAV2 | neuron navigator 2 | 0.0390948 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0386357 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0347315 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0342936 |
| RCOR1 | REST corepressor 1 | 0.0335409 |
| FAM13A | family with sequence similarity 13, member A | 0.0334463 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0331953 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0330238 |
| PLEC | plectin | 0.0329414 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0324439 |
| CCNL1 | cyclin L1 | 0.0324126 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0322002 |
| BRD2 | bromodomain containing 2 | 0.0315447 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0314505 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0306548 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0304738 |
| JUP | junction plakoglobin | 0.0302236 |
| IRF6 | interferon regulatory factor 6 | 0.0301546 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0301105 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0297934 |
| YTHDC1 | YTH domain containing 1 | 0.0294687 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0291535 |
| DUSP10 | dual specificity phosphatase 10 | 0.0291464 |
| KRT8 | keratin 8, type II | 0.0288988 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0283224 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0277443 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0272963 |
| FNIP1 | folliculin interacting protein 1 | 0.0272795 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0267587 |
| EP300 | E1A binding protein p300 | 0.0265575 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0264474 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0263936 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0262544 |
| ZNF148 | zinc finger protein 148 | 0.0258991 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0256778 |
| HDGF | hepatoma-derived growth factor | 0.0253012 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0250928 |
| CCNY | cyclin Y | 0.0249999 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0247448 |
| ARRDC3 | arrestin domain containing 3 | 0.0247189 |
| RPL3 | ribosomal protein L3 | 0.024593 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0244599 |
| GOLGB1 | golgin B1 | 0.0242356 |
| MCL1 | myeloid cell leukemia 1 | 0.0241758 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0240685 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0237037 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0234641 |
| EFNA5 | ephrin-A5 | 0.023449 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.023154 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.023145 |
| BBX | bobby sox homolog (Drosophila) | 0.0229312 |
| MYO5B | myosin VB | 0.0225389 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0222092 |
| NUP98 | nucleoporin 98kDa | 0.0221351 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0221172 |
| SRP54 | signal recognition particle 54kDa | 0.0220615 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0218876 |
| KIF5B | kinesin family member 5B | 0.0217441 |
| HELZ | helicase with zinc finger | 0.0216732 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0216478 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0213964 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0213392 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0211695 |
| MKRN1 | makorin ring finger protein 1 | 0.0208601 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0206454 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.02061 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0205357 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0205197 |
| CDK7 | cyclin-dependent kinase 7 | 0.0200523 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0199558 |
| ANXA1 | annexin A1 | 0.0197963 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0195546 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0193877 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0193802 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.019171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.277943 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197977 |
| TMSB10 | thymosin beta 10 | -0.179078 |
| UBC | ubiquitin C | -0.126123 |
| S100A6 | S100 calcium binding protein A6 | -0.108856 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106725 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.101917 |
| S100A10 | S100 calcium binding protein A10 | -0.094284 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.078999 |
| RPL35A | ribosomal protein L35a | -0.0709675 |
| RPL34 | ribosomal protein L34 | -0.0700319 |
| ASPH | aspartate beta-hydroxylase | -0.0660089 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0647069 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0638174 |
| KRT7 | keratin 7, type II | -0.0627435 |
| FTL | ferritin, light polypeptide | -0.0615724 |
| PTMA | prothymosin, alpha | -0.0604246 |
| MT2A | metallothionein 2A | -0.059694 |
| RPL23 | ribosomal protein L23 | -0.0561728 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0529163 |
| SDC4 | syndecan 4 | -0.0527869 |
| SQSTM1 | sequestosome 1 | -0.0520659 |
| RPS23 | ribosomal protein S23 | -0.0514812 |
| RPLP2 | ribosomal protein, large, P2 | -0.0509823 |
| RPLP1 | ribosomal protein, large, P1 | -0.0501797 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0500022 |
| RPL8 | ribosomal protein L8 | -0.0494136 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0493646 |
| RPS27A | ribosomal protein S27a | -0.0488191 |
| RPL32 | ribosomal protein L32 | -0.0487837 |
| ENO1 | enolase 1, (alpha) | -0.0476494 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0468237 |
| LAMC2 | laminin, gamma 2 | -0.0460395 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0460361 |
| HMGA1 | high mobility group AT-hook 1 | -0.0459406 |
| RPS19 | ribosomal protein S19 | -0.0458157 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0451879 |
| CCND1 | cyclin D1 | -0.0428469 |
| RPL12 | ribosomal protein L12 | -0.0425174 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0400395 |
| RPL19 | ribosomal protein L19 | -0.039644 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0387903 |
| ANXA2 | annexin A2 | -0.0387743 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0387272 |
| AHNAK | AHNAK nucleoprotein | -0.0385725 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0364689 |
| RPS8 | ribosomal protein S8 | -0.0357806 |
| AREG | amphiregulin | -0.0353502 |
| LMO7 | LIM domain 7 | -0.0343293 |
| TOP1 | topoisomerase (DNA) I | -0.0341396 |
| RPS13 | ribosomal protein S13 | -0.0339696 |
| LDHA | lactate dehydrogenase A | -0.0339551 |
| RPS21 | ribosomal protein S21 | -0.0335635 |
| ARF1 | ADP-ribosylation factor 1 | -0.0334691 |
| CCNI | cyclin I | -0.0334507 |
| G0S2 | G0/G1 switch 2 | -0.0333551 |
| HMGB2 | high mobility group box 2 | -0.0333182 |
| GNAS | GNAS complex locus | -0.0322465 |
| TMEM263 | transmembrane protein 263 | -0.0321245 |
| EPCAM | epithelial cell adhesion molecule | -0.0316944 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.03159 |
| S100A11 | S100 calcium binding protein A11 | -0.0315283 |
| KLF6 | Kruppel-like factor 6 | -0.0311498 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.0311326 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0306071 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0294029 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0291661 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0290285 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.028745 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0286771 |
| RPS29 | ribosomal protein S29 | -0.0286246 |
| RPLP0 | ribosomal protein, large, P0 | -0.0286117 |
| FAM162A | family with sequence similarity 162, member A | -0.0283522 |
| RPS24 | ribosomal protein S24 | -0.0281593 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0278357 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0278308 |
| PLAU | plasminogen activator, urokinase | -0.0274576 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0273238 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0270581 |
| CD9 | CD9 molecule | -0.026864 |
| RPL31 | ribosomal protein L31 | -0.026841 |
| RPS3 | ribosomal protein S3 | -0.0267461 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0267363 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0266928 |
| RPS14 | ribosomal protein S14 | -0.0266219 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0258951 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0258217 |
| SP100 | SP100 nuclear antigen | -0.0256669 |
| TKT | transketolase | -0.025627 |
| RPL27A | ribosomal protein L27a | -0.025247 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0252151 |
| RPL11 | ribosomal protein L11 | -0.025184 |
| RPS16 | ribosomal protein S16 | -0.0250365 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0249115 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0244364 |
| RPS5 | ribosomal protein S5 | -0.0244069 |
| RPL9 | ribosomal protein L9 | -0.0241424 |
| EREG | epiregulin | -0.0240118 |
| HMGB1 | high mobility group box 1 | -0.0236302 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0235634 |
