| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.207354 |
| PM20D1 | peptidase M20 domain containing 1 | 0.134165 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.118957 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.115678 |
| COL5A2 | collagen, type V, alpha 2 | 0.110035 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.108379 |
| PDE10A | phosphodiesterase 10A | 0.10695 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.092711 |
| GRAMD1B | GRAM domain containing 1B | 0.0888892 |
| MYOF | myoferlin | 0.0879769 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.083997 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0785924 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.073058 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0718385 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0679 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0665034 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.06622 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0610427 |
| PGK1 | phosphoglycerate kinase 1 | 0.0600473 |
| DST | dystonin | 0.0580036 |
| ASPH | aspartate beta-hydroxylase | 0.0569907 |
| LDHA | lactate dehydrogenase A | 0.0552773 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.055191 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0526627 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0525195 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0523795 |
| GDA | guanine deaminase | 0.0514308 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0478732 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0478394 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0465799 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0453886 |
| FLNB | filamin B, beta | 0.043843 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0424313 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0416095 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0413071 |
| EZR | ezrin | 0.0402123 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0399485 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0395136 |
| VIM | vimentin | 0.0394324 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0387395 |
| ANXA2 | annexin A2 | 0.0381444 |
| FMNL2 | formin-like 2 | 0.0380733 |
| CANX | calnexin | 0.036957 |
| ANXA1 | annexin A1 | 0.0365296 |
| B2M | beta-2-microglobulin | 0.0362882 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0361048 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0360915 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0360036 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0358562 |
| ENO1 | enolase 1, (alpha) | 0.0357329 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0355298 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0353978 |
| OGA | O-GlcNAcase | 0.0352152 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0352051 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0348953 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0344589 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0339597 |
| PKM | pyruvate kinase, muscle | 0.0330787 |
| PCBP3 | poly(rC) binding protein 3 | 0.0330169 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0329146 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0326497 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0325569 |
| UBC | ubiquitin C | 0.0324113 |
| AHNAK | AHNAK nucleoprotein | 0.0318522 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.03161 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0314079 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0313044 |
| KYNU | kynureninase | 0.0311613 |
| TXNRD1 | thioredoxin reductase 1 | 0.0308782 |
| XPO1 | exportin 1 | 0.030878 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.030731 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0303319 |
| FAM13A | family with sequence similarity 13, member A | 0.0298766 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0297597 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0294794 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.029284 |
| DNER | delta/notch-like EGF repeat containing | 0.0290924 |
| RGS2 | regulator of G-protein signaling 2 | 0.0289635 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0287552 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0279071 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0277409 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0277316 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0277274 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0267841 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0267123 |
| CUL4B | cullin 4B | 0.0266683 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.025879 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0257449 |
| FAM107B | family with sequence similarity 107, member B | 0.0256969 |
| MCL1 | myeloid cell leukemia 1 | 0.0256162 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0254798 |
| HELZ | helicase with zinc finger | 0.0251849 |
| HLA-A | major histocompatibility complex, class I, A | 0.0250875 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.024819 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0247698 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0245937 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0245437 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0244955 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0244751 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0244613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.112407 |
| CDH13 | cadherin 13 | -0.0783198 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0752361 |
| SMYD3 | SET and MYND domain containing 3 | -0.052166 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0507218 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0495507 |
| NCKAP5 | NCK-associated protein 5 | -0.0466186 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0423491 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0422538 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0403311 |
| LSAMP | limbic system-associated membrane protein | -0.0347659 |
| RPS24 | ribosomal protein S24 | -0.0315925 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0290985 |
| CADM2 | cell adhesion molecule 2 | -0.028803 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.027576 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0268847 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0259924 |
| RPL9 | ribosomal protein L9 | -0.0253468 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.0240802 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0234717 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0232013 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0217622 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0217072 |
| KIAA0825 | KIAA0825 | -0.0211428 |
| TENM3 | teneurin transmembrane protein 3 | -0.020797 |
| RPL31 | ribosomal protein L31 | -0.0201768 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.020088 |
| CDK13 | cyclin-dependent kinase 13 | -0.0192636 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0191503 |
| STEAP1B | STEAP family member 1B | -0.0190474 |
| RPL26 | ribosomal protein L26 | -0.0189019 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0188492 |
| UBAP2 | ubiquitin associated protein 2 | -0.0183832 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | -0.0183116 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0181606 |
| RANBP17 | RAN binding protein 17 | -0.0180367 |
| EXOC4 | exocyst complex component 4 | -0.0180099 |
| RPS21 | ribosomal protein S21 | -0.0177083 |
| FNIP1 | folliculin interacting protein 1 | -0.017671 |
| RPS13 | ribosomal protein S13 | -0.017414 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0173284 |
| EFNA5 | ephrin-A5 | -0.0169519 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0168941 |
| RPS3 | ribosomal protein S3 | -0.0168938 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0167041 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.016694 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0165915 |
| RPS12 | ribosomal protein S12 | -0.0165732 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0163799 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0161223 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0157616 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0157076 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0156997 |
| JMJD1C | jumonji domain containing 1C | -0.0156302 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0155889 |
| PTMA | prothymosin, alpha | -0.0154229 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0152975 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0149388 |
| COMMD10 | COMM domain containing 10 | -0.014767 |
| RPS17 | ribosomal protein S17 | -0.0147295 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0146579 |
| SFPQ | splicing factor proline/glutamine-rich | -0.014155 |
| NDUFAF2 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 | -0.0139971 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0137447 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0136008 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0135403 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0134405 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.0134224 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 | -0.0133742 |
| NTN4 | netrin 4 | -0.0132906 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0132872 |
| AEBP2 | AE binding protein 2 | -0.0131254 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0131206 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0126684 |
| PCDH9 | protocadherin 9 | -0.0124654 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0124357 |
| WDR43 | WD repeat domain 43 | -0.0123925 |
| ZNF644 | zinc finger protein 644 | -0.0123917 |
| PAPPA2 | pappalysin 2 | -0.0123902 |
| RPS19 | ribosomal protein S19 | -0.012322 |
| RPL23 | ribosomal protein L23 | -0.012256 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0122514 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0121943 |
| CMIP | c-Maf inducing protein | -0.0121478 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0120771 |
| RPL36A | ribosomal protein L36a | -0.0120726 |
| AUTS2 | autism susceptibility candidate 2 | -0.0120463 |
| CCDC138 | coiled-coil domain containing 138 | -0.0119029 |
| RPLP2 | ribosomal protein, large, P2 | -0.011886 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0116365 |
| RPS25 | ribosomal protein S25 | -0.0115632 |
| PRSS23 | protease, serine, 23 | -0.0115026 |
| RBM6 | RNA binding motif protein 6 | -0.011461 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0114435 |
| TBCA | tubulin folding cofactor A | -0.0113265 |
| RPL34 | ribosomal protein L34 | -0.0112508 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0112376 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.011123 |
| CCDC91 | coiled-coil domain containing 91 | -0.0110955 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0110694 |
