| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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131 genes differentially expressed following the Adenine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.236273 |
| GPC6 | glypican 6 | 0.139707 |
| MMP1 | matrix metallopeptidase 1 | 0.115618 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.113969 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.100717 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0942481 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0849209 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0804999 |
| ZNF292 | zinc finger protein 292 | 0.0782958 |
| HMGA2 | high mobility group AT-hook 2 | 0.0640303 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0636404 |
| APP | amyloid beta (A4) precursor protein | 0.0621496 |
| FMNL2 | formin-like 2 | 0.0543874 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0519386 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0481005 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.0455367 |
| MYO1E | myosin IE | 0.0449663 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0446314 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.04246 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0414218 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.040726 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0386122 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0367136 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0318972 |
| JMJD1C | jumonji domain containing 1C | 0.0317559 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0316996 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0283311 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.027545 |
| GLIS3 | GLIS family zinc finger 3 | 0.0262859 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0261245 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0252397 |
| ITGB4 | integrin, beta 4 | 0.0249359 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.022883 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0217832 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.0215485 |
| PDE8A | phosphodiesterase 8A | 0.0189877 |
| ASPH | aspartate beta-hydroxylase | 0.0183157 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0179299 |
| PTMA | prothymosin, alpha | 0.0177518 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0174848 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0171536 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0165334 |
| SBF2 | SET binding factor 2 | 0.0148602 |
| FN1 | fibronectin 1 | 0.0139627 |
| PTK2 | protein tyrosine kinase 2 | 0.0135316 |
| NAV2 | neuron navigator 2 | 0.0120938 |
| TRPM5 | transient receptor potential cation channel, subfamily M, member 5 | 0.0109966 |
| SRPK2 | SRSF protein kinase 2 | 0.0101284 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.00860701 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.00845655 |
| TCF12 | transcription factor 12 | 0.00840588 |
| LMO7 | LIM domain 7 | 0.00770876 |
| SETD5 | SET domain containing 5 | 0.0072405 |
| SLTM | SAFB-like, transcription modulator | 0.00685976 |
| CD44 | CD44 molecule (Indian blood group) | 0.00635021 |
| FLNB | filamin B, beta | 0.00566176 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.00558893 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.00504842 |
| DIAPH2 | diaphanous-related formin 2 | 0.00501712 |
| PARD3 | par-3 family cell polarity regulator | 0.00453371 |
| ACTN4 | actinin, alpha 4 | 0.00373392 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0012405 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 5.23467E-4 |
| NPAS2 | neuronal PAS domain protein 2 | 2.95028E-5 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.192882 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.121937 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.119226 |
| TMSB10 | thymosin beta 10 | -0.115699 |
| VIM | vimentin | -0.0963815 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0911326 |
| CDH13 | cadherin 13 | -0.0814559 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0808089 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0806698 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0770848 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0753097 |
| CADM2 | cell adhesion molecule 2 | -0.0708895 |
| SPAG9 | sperm associated antigen 9 | -0.0701589 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0638425 |
| EFNA5 | ephrin-A5 | -0.063421 |
| INHBA | inhibin, beta A | -0.0633101 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0589386 |
| MYOF | myoferlin | -0.0554885 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0547757 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0511515 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0511393 |
| DST | dystonin | -0.047146 |
| AOPEP | aminopeptidase O (putative) | -0.0450099 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.039301 |
| EGFR | epidermal growth factor receptor | -0.0383748 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0374018 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.033727 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0328809 |
| PGK1 | phosphoglycerate kinase 1 | -0.0320315 |
| DOCK4 | dedicator of cytokinesis 4 | -0.029795 |
| PDE10A | phosphodiesterase 10A | -0.0294886 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0290307 |
| TXNRD1 | thioredoxin reductase 1 | -0.0283236 |
| NDRG1 | N-myc downstream regulated 1 | -0.027817 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0260943 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0248367 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0238278 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0219934 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0216303 |
| KRT18 | keratin 18, type I | -0.0198938 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0190373 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0189442 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.018669 |
| MYO10 | myosin X | -0.0171824 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0148247 |
| PEG10 | paternally expressed 10 | -0.0144122 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0140385 |
| RIGI | RNA sensor RIG-I | -0.0118553 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0113952 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0112503 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0109675 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00955897 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.00901404 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.00863612 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00819064 |
| LDHA | lactate dehydrogenase A | -0.00779247 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.00776287 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.00744302 |
| PRKD3 | protein kinase D3 | -0.00736375 |
| STC1 | stanniocalcin 1 | -0.00706239 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00703463 |
| FNDC3A | fibronectin type III domain containing 3A | -0.00617428 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00613333 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.00554532 |
| ANTXR1 | anthrax toxin receptor 1 | -0.00552978 |
| POTEF | POTE ankyrin domain family, member F | -0.00470596 |
| BBX | bobby sox homolog (Drosophila) | -0.0010771 |
