| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.125804 |
| VEGFA | vascular endothelial growth factor A | 0.111915 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.104033 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.100054 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0989028 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0965272 |
| SFTPA2 | surfactant protein A2 | 0.0634955 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0634271 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0629384 |
| INTS6 | integrator complex subunit 6 | 0.0612799 |
| ADM | adrenomedullin | 0.0590853 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0582451 |
| COL5A1 | collagen, type V, alpha 1 | 0.0581829 |
| B2M | beta-2-microglobulin | 0.0571499 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0558428 |
| NDRG1 | N-myc downstream regulated 1 | 0.0552979 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.055093 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0523294 |
| HDAC9 | histone deacetylase 9 | 0.0517529 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0517389 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.051338 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0505065 |
| RND3 | Rho family GTPase 3 | 0.050241 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0492282 |
| PCBP2 | poly(rC) binding protein 2 | 0.0461995 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.045472 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0439969 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0433014 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0425909 |
| MSN | moesin | 0.0425825 |
| DUSP10 | dual specificity phosphatase 10 | 0.04198 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0418486 |
| CALR | calreticulin | 0.040279 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0397141 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0390015 |
| SQSTM1 | sequestosome 1 | 0.0383687 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0383428 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0382828 |
| BRD2 | bromodomain containing 2 | 0.0377957 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0370972 |
| MLPH | melanophilin | 0.0360586 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0355327 |
| C3 | complement component 3 | 0.0352219 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0349776 |
| CDH13 | cadherin 13 | 0.0339381 |
| TSC22D2 | TSC22 domain family, member 2 | 0.033406 |
| FMNL2 | formin-like 2 | 0.033328 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0320962 |
| LDHA | lactate dehydrogenase A | 0.030227 |
| YBX1 | Y box binding protein 1 | 0.0299292 |
| CANX | calnexin | 0.0298539 |
| FLNA | filamin A, alpha | 0.0295175 |
| IRS2 | insulin receptor substrate 2 | 0.0291862 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0289083 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0288855 |
| HELZ | helicase with zinc finger | 0.0287474 |
| HMGA2 | high mobility group AT-hook 2 | 0.0286862 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0281556 |
| FBXO32 | F-box protein 32 | 0.0274178 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0272771 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.026752 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0265861 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0265853 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0265048 |
| PLIN2 | perilipin 2 | 0.026101 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0260408 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0259307 |
| RYBP | RING1 and YY1 binding protein | 0.0255411 |
| HLA-A | major histocompatibility complex, class I, A | 0.0248267 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0247624 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0245995 |
| OPTN | optineurin | 0.0245275 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.024527 |
| CEP250 | centrosomal protein 250kDa | 0.0241473 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0235401 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0235389 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0234784 |
| RACK1 | receptor for activated C kinase 1 | 0.0232881 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0227151 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0224831 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0224002 |
| MYO10 | myosin X | 0.0223751 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0222861 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0222411 |
| RNF213 | ring finger protein 213 | 0.0220908 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0219613 |
| POTEF | POTE ankyrin domain family, member F | 0.021597 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0212434 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0212134 |
| SNX3 | sorting nexin 3 | 0.0211027 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.021062 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0209525 |
| STC2 | stanniocalcin 2 | 0.0208924 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0208427 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0206558 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0201955 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0201726 |
| DEPP1 | DEPP autophagy regulator 1 | 0.019985 |
| TLE4 | transducin-like enhancer of split 4 | 0.0195136 |
| RPS6 | ribosomal protein S6 | 0.01942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.169108 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.142203 |
| VCL | vinculin | -0.0977775 |
| FRMD4A | FERM domain containing 4A | -0.0846158 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0784014 |
| BICC1 | BicC family RNA binding protein 1 | -0.0693188 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0692034 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0690107 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0641471 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0612963 |
| MKI67 | marker of proliferation Ki-67 | -0.0593339 |
| TPM4 | tropomyosin 4 | -0.0577458 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0566884 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0547806 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0537756 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0535684 |
| JMJD1C | jumonji domain containing 1C | -0.0530616 |
| KLF6 | Kruppel-like factor 6 | -0.0524608 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0508715 |
| GLIS3 | GLIS family zinc finger 3 | -0.050767 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0492829 |
| CENPF | centromere protein F, 350/400kDa | -0.0487979 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0483172 |
| OSMR | oncostatin M receptor | -0.0480597 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0467978 |
| THBS1 | thrombospondin 1 | -0.0466182 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0462311 |
| VIM | vimentin | -0.0453229 |
| PGK1 | phosphoglycerate kinase 1 | -0.0433791 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0432305 |
| RTN4 | reticulon 4 | -0.0431751 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0418728 |
| SBF2 | SET binding factor 2 | -0.0417311 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0379367 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0377009 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0371609 |
| TMSB10 | thymosin beta 10 | -0.0363324 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0360432 |
| CDCP1 | CUB domain containing protein 1 | -0.0358202 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0352861 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0352011 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0351429 |
| RPS24 | ribosomal protein S24 | -0.0345356 |
| SMYD3 | SET and MYND domain containing 3 | -0.0341669 |
| SYAP1 | synapse associated protein 1 | -0.032851 |
| NF1 | neurofibromin 1 | -0.0323667 |
| CD44 | CD44 molecule (Indian blood group) | -0.0316323 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0314684 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0312256 |
| TXNRD1 | thioredoxin reductase 1 | -0.0308586 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.030554 |
| KIF4A | kinesin family member 4A | -0.0305256 |
| RAI14 | retinoic acid induced 14 | -0.0301095 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0299505 |
| FRMD5 | FERM domain containing 5 | -0.0299182 |
| HLA-B | major histocompatibility complex, class I, B | -0.0294673 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0292965 |
| DIAPH3 | diaphanous-related formin 3 | -0.0291165 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0284117 |
| CLIC4 | chloride intracellular channel 4 | -0.0280175 |
| KLHL5 | kelch-like family member 5 | -0.0277242 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0274463 |
| TUBB | tubulin, beta class I | -0.0272472 |
| RBM39 | RNA binding motif protein 39 | -0.02703 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0269494 |
| ATXN1 | ataxin 1 | -0.0267336 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0267073 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0265604 |
| MAP4 | microtubule-associated protein 4 | -0.0264184 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.026347 |
| ANLN | anillin, actin binding protein | -0.0263408 |
| PALLD | palladin, cytoskeletal associated protein | -0.0262487 |
| RPL36A | ribosomal protein L36a | -0.0258359 |
| RRBP1 | ribosome binding protein 1 | -0.0258199 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0256824 |
| RPS21 | ribosomal protein S21 | -0.0250077 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0246857 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0246072 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0242913 |
| HDAC8 | histone deacetylase 8 | -0.0242165 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0241608 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0240152 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0238168 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0238062 |
| PTMA | prothymosin, alpha | -0.0237007 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0236776 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0236675 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0236603 |
| TMEM41B | transmembrane protein 41B | -0.0236055 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0230299 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0230107 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0228448 |
| RASA2 | RAS p21 protein activator 2 | -0.022844 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0228439 |
| CEP95 | centrosomal protein 95kDa | -0.0227537 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0224022 |
| CAB39 | calcium binding protein 39 | -0.022285 |
| MT2A | metallothionein 2A | -0.0220263 |
| CD2AP | CD2-associated protein | -0.0218753 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0217915 |
