| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.146394 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0556532 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.055547 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0489152 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0471869 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0444083 |
| ANXA1 | annexin A1 | 0.044361 |
| DNER | delta/notch-like EGF repeat containing | 0.0442911 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0430781 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0416158 |
| YAP1 | Yes-associated protein 1 | 0.0406072 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0382221 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0373042 |
| TXNRD1 | thioredoxin reductase 1 | 0.036179 |
| NUP58 | nucleoporin 58 | 0.0353792 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0346917 |
| ANLN | anillin, actin binding protein | 0.0337245 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0337036 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0334682 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0323779 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0315716 |
| TXNIP | thioredoxin interacting protein | 0.0314796 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0305589 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0303503 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0299112 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0289517 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0282026 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0280125 |
| DIAPH3 | diaphanous-related formin 3 | 0.0279059 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0266364 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0265259 |
| RNF145 | ring finger protein 145 | 0.025993 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.025952 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0258916 |
| KIF5B | kinesin family member 5B | 0.025839 |
| FAM168A | family with sequence similarity 168, member A | 0.0258185 |
| COPA | coatomer protein complex, subunit alpha | 0.0256965 |
| XPO1 | exportin 1 | 0.025603 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0255586 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0253795 |
| SMAD3 | SMAD family member 3 | 0.0252068 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0248286 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0248097 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0247343 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0245798 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0244229 |
| RANBP2 | RAN binding protein 2 | 0.0243437 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.023911 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.023726 |
| CEP250 | centrosomal protein 250kDa | 0.0235052 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0234051 |
| CENPE | centromere protein E, 312kDa | 0.0232327 |
| APP | amyloid beta (A4) precursor protein | 0.0231252 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.023026 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0230026 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0227925 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0225425 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0224011 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0222853 |
| KIF1B | kinesin family member 1B | 0.0221306 |
| TPX2 | TPX2, microtubule-associated | 0.0220997 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0220934 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0220824 |
| PUM2 | pumilio RNA-binding family member 2 | 0.021933 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.021914 |
| GOLGA4 | golgin A4 | 0.0217548 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.02137 |
| FAM13A | family with sequence similarity 13, member A | 0.0211504 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0211421 |
| STRBP | spermatid perinuclear RNA binding protein | 0.0210696 |
| PDE10A | phosphodiesterase 10A | 0.0209421 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0208889 |
| CANX | calnexin | 0.0207644 |
| ARRDC3 | arrestin domain containing 3 | 0.0207531 |
| DMXL2 | Dmx-like 2 | 0.020703 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0206744 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0204228 |
| HDLBP | high density lipoprotein binding protein | 0.0203429 |
| IPO5 | importin 5 | 0.0200211 |
| SSH2 | slingshot protein phosphatase 2 | 0.019769 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0197013 |
| SRPK2 | SRSF protein kinase 2 | 0.0196872 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0196647 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0195422 |
| PNN | pinin, desmosome associated protein | 0.0195078 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0194764 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0194106 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0193965 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0192553 |
| SUCO | SUN domain containing ossification factor | 0.0192235 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0191438 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0191363 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0190058 |
| CEP290 | centrosomal protein 290kDa | 0.0188792 |
| OXSR1 | oxidative stress responsive 1 | 0.0188684 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0188334 |
| ZNF670 | zinc finger protein 670 | 0.0188224 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0187522 |
| PCM1 | pericentriolar material 1 | 0.0187334 |
| RCAN1 | regulator of calcineurin 1 | 0.0186389 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.16521 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.160401 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130042 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.11354 |
| TMSB10 | thymosin beta 10 | -0.0974874 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0942418 |
| PRSS23 | protease, serine, 23 | -0.08211 |
| PRKCA | protein kinase C, alpha | -0.0803192 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0765552 |
| HMGA2 | high mobility group AT-hook 2 | -0.0737393 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0721989 |
| DST | dystonin | -0.0705723 |
| LDHA | lactate dehydrogenase A | -0.0693823 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0683472 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0666288 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0655558 |
| RSF1 | remodeling and spacing factor 1 | -0.0579489 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0563839 |
| PRR16 | proline rich 16 | -0.055174 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0541695 |
| RAI14 | retinoic acid induced 14 | -0.0541108 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0531116 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0530676 |
| RAD51B | RAD51 paralog B | -0.0501182 |
| NAV3 | neuron navigator 3 | -0.0495364 |
| ANGPTL4 | angiopoietin-like 4 | -0.0487255 |
| NAV2 | neuron navigator 2 | -0.0487181 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0485502 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0475675 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0474201 |
| IER3 | immediate early response 3 | -0.0470998 |
| SVIL | supervillin | -0.046474 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0462576 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0460057 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0457694 |
| PARD3 | par-3 family cell polarity regulator | -0.0451236 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0445574 |
| VCL | vinculin | -0.0439932 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0435868 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0435329 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0420791 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0417415 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0415389 |
| NALCN | sodium leak channel, non selective | -0.0412034 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0407113 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0405421 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.04022 |
| OSMR | oncostatin M receptor | -0.0400524 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0398301 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0396522 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0396462 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0393212 |
| SDC4 | syndecan 4 | -0.039064 |
| S100A10 | S100 calcium binding protein A10 | -0.0386556 |
| ENO1 | enolase 1, (alpha) | -0.0386305 |
| ERBIN | erbb2 interacting protein | -0.0370102 |
| BPTF | bromodomain PHD finger transcription factor | -0.0366352 |
| GNAS | GNAS complex locus | -0.0364377 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0364241 |
| TBCA | tubulin folding cofactor A | -0.0362168 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0362091 |
| RPL35A | ribosomal protein L35a | -0.0353328 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0352793 |
| SMYD3 | SET and MYND domain containing 3 | -0.0351538 |
| EGFR | epidermal growth factor receptor | -0.0351466 |
| RBM25 | RNA binding motif protein 25 | -0.0348954 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0347834 |
| PODXL | podocalyxin-like | -0.0345712 |
| GPATCH2L | G patch domain containing 2-like | -0.0343008 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0342485 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0337174 |
| LMO7 | LIM domain 7 | -0.0335132 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0327894 |
| MT2A | metallothionein 2A | -0.0327054 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0320556 |
| FMN1 | formin 1 | -0.0313334 |
| PGK1 | phosphoglycerate kinase 1 | -0.0313215 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0312625 |
| FBXO11 | F-box protein 11 | -0.0312317 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0312091 |
| AEBP2 | AE binding protein 2 | -0.0306182 |
| RPL9 | ribosomal protein L9 | -0.0305865 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0304295 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0304218 |
| RPS3 | ribosomal protein S3 | -0.0303746 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0300167 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0288551 |
| CCND1 | cyclin D1 | -0.0287698 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0285316 |
| PRELID2 | PRELI domain containing 2 | -0.0284159 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0283925 |
| RIGI | RNA sensor RIG-I | -0.0283838 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0280533 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0278533 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0277352 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0275798 |
| S100A6 | S100 calcium binding protein A6 | -0.0275604 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0275588 |
| B2M | beta-2-microglobulin | -0.027462 |
| RPL36 | ribosomal protein L36 | -0.0270752 |
