| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenine perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenine_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.103523 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0668315 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0565663 |
| VEGFA | vascular endothelial growth factor A | 0.0560286 |
| SMAD3 | SMAD family member 3 | 0.0544257 |
| B2M | beta-2-microglobulin | 0.0539763 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0481758 |
| TMEM156 | transmembrane protein 156 | 0.0475702 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0453578 |
| TXNIP | thioredoxin interacting protein | 0.0446425 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0423649 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0419668 |
| RNF145 | ring finger protein 145 | 0.0387368 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0384284 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0381037 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0379225 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0373816 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0372829 |
| NTN4 | netrin 4 | 0.0325145 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0314171 |
| TXNRD1 | thioredoxin reductase 1 | 0.0301359 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0295278 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0289358 |
| SFTPA2 | surfactant protein A2 | 0.0288354 |
| NEK7 | NIMA-related kinase 7 | 0.0283718 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0278628 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278388 |
| NRP1 | neuropilin 1 | 0.0274558 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0273989 |
| SEPTIN9 | septin 9 | 0.0270488 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0268816 |
| CALR | calreticulin | 0.0264376 |
| YBX3 | Y box binding protein 3 | 0.0262179 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.025346 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0252546 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0251147 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0247672 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0244773 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0240183 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0236831 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0234498 |
| CDC73 | cell division cycle 73 | 0.0234107 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0226564 |
| PRPF8 | pre-mRNA processing factor 8 | 0.021992 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0217151 |
| COPA | coatomer protein complex, subunit alpha | 0.0216835 |
| RLF | rearranged L-myc fusion | 0.0216798 |
| GOLGA4 | golgin A4 | 0.0216218 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0208429 |
| NUP58 | nucleoporin 58 | 0.0206025 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0203568 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0202161 |
| RACK1 | receptor for activated C kinase 1 | 0.0201321 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0199568 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.019937 |
| SRPK2 | SRSF protein kinase 2 | 0.0197521 |
| NOP58 | NOP58 ribonucleoprotein | 0.0196889 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0194453 |
| PELO | pelota homolog (Drosophila) | 0.0194296 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.01941 |
| SVIL | supervillin | 0.0193235 |
| FAT1 | FAT atypical cadherin 1 | 0.0191709 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0189976 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0189334 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0188812 |
| KSR1 | kinase suppressor of ras 1 | 0.0188281 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0187523 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0186904 |
| TPR | translocated promoter region, nuclear basket protein | 0.0183511 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.018351 |
| POTEF | POTE ankyrin domain family, member F | 0.0183035 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.018298 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0181391 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0181355 |
| YBX1 | Y box binding protein 1 | 0.0180558 |
| FNBP1 | formin binding protein 1 | 0.0177386 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0175738 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0175645 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0175485 |
| WDR45B | WD repeat domain 45B | 0.01739 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0173796 |
| TOP1 | topoisomerase (DNA) I | 0.0173611 |
| SETD5 | SET domain containing 5 | 0.0171358 |
| HELZ | helicase with zinc finger | 0.0170966 |
| MTMR3 | myotubularin related protein 3 | 0.0169991 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0169737 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0169558 |
| WDR26 | WD repeat domain 26 | 0.0168367 |
| TPM3 | tropomyosin 3 | 0.0167851 |
| SIK3 | SIK family kinase 3 | 0.0167707 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0167543 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0167167 |
| YTHDC1 | YTH domain containing 1 | 0.0166746 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0166232 |
| SLTM | SAFB-like, transcription modulator | 0.0163765 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0163397 |
| ETNK1 | ethanolamine kinase 1 | 0.0161371 |
| SUCO | SUN domain containing ossification factor | 0.0161271 |
| KLHDC10 | kelch domain containing 10 | 0.0161146 |
| IL6ST | interleukin 6 signal transducer | 0.0160789 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.24997 |
| FN1 | fibronectin 1 | -0.157195 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.11622 |
| HMGA2 | high mobility group AT-hook 2 | -0.0997126 |
| ASPH | aspartate beta-hydroxylase | -0.0679488 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0599576 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0585269 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0574418 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0574371 |
| SQSTM1 | sequestosome 1 | -0.0568742 |
| VCL | vinculin | -0.0551583 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0551233 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0489919 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0481002 |
| RAI14 | retinoic acid induced 14 | -0.0473351 |
| AEBP2 | AE binding protein 2 | -0.047152 |
| TMSB10 | thymosin beta 10 | -0.0468256 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0448527 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0445534 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0405376 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0391898 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0383131 |
| INTS6 | integrator complex subunit 6 | -0.0380242 |
| LRRC23 | leucine rich repeat containing 23 | -0.0369036 |
| EFNA5 | ephrin-A5 | -0.0365755 |
| HLA-B | major histocompatibility complex, class I, B | -0.0355108 |
| NDRG1 | N-myc downstream regulated 1 | -0.0352909 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0347235 |
| SYT1 | synaptotagmin I | -0.0339454 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0339302 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0320309 |
| RAD51B | RAD51 paralog B | -0.0318037 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.029823 |
| GLIS3 | GLIS family zinc finger 3 | -0.0296041 |
| TMSB4X | thymosin beta 4, X-linked | -0.0295842 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0282698 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0279803 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0272507 |
| CADM1 | cell adhesion molecule 1 | -0.0272219 |
| ITGA1 | integrin, alpha 1 | -0.0269283 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0267856 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0265063 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.025886 |
| VIM | vimentin | -0.0255501 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0254604 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0254362 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0251095 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0247557 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0247151 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0234712 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0234515 |
| GPC6 | glypican 6 | -0.0234287 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0231337 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0229193 |
| TGFA | transforming growth factor, alpha | -0.022685 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0224645 |
| MYOF | myoferlin | -0.022456 |
| TENM4 | teneurin transmembrane protein 4 | -0.0224275 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0223464 |
| CUX1 | cut-like homeobox 1 | -0.0220863 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0220239 |
| ACTG1 | actin gamma 1 | -0.0212723 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0211898 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0211169 |
| GNAS | GNAS complex locus | -0.0211145 |
| PRKCA | protein kinase C, alpha | -0.0209933 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0209771 |
| CCDC138 | coiled-coil domain containing 138 | -0.0198722 |
| FHIT | fragile histidine triad | -0.0192909 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.019261 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0192236 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0188436 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0186808 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0184337 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0179379 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.017901 |
| FAM20C | family with sequence similarity 20, member C | -0.0178146 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0177149 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0174153 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0173729 |
| S100A6 | S100 calcium binding protein A6 | -0.0172685 |
| TNS3 | tensin 3 | -0.0170314 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0169748 |
| NABP1 | nucleic acid binding protein 1 | -0.0168495 |
| CTSD | cathepsin D | -0.0166107 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0164914 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0163946 |
| TUFT1 | tuftelin 1 | -0.0163834 |
| S100A10 | S100 calcium binding protein A10 | -0.0161747 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0157443 |
| HM13 | histocompatibility (minor) 13 | -0.0155868 |
| ETV6 | ets variant 6 | -0.0155361 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0155057 |
| SUMF1 | sulfatase modifying factor 1 | -0.0154182 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0152572 |
| TMEM165 | transmembrane protein 165 | -0.0151306 |
| NBEA | neurobeachin | -0.0150003 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0149222 |
| ACOXL | acyl-CoA oxidase-like | -0.0148944 |
| RPS21 | ribosomal protein S21 | -0.0146422 |
