Adenocarcinoma Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A type of carcinoma derived from glandular tissue or in which tumor cells form recognizable glandular structures.|A malignant epithelial tumor with a glandular organization. (Experimental Factor Ontology, EFO_0000228)
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Genes

200 genes associated with the disease Adenocarcinoma in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
TERT telomerase reverse transcriptase 2.056
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 2.055
CLPTM1L CLPTM1-like 2.055
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 2.052
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.048
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 2.042
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 2.042
HYKK hydroxylysine kinase 2.024
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 2.024
TPRG1 tumor protein p63 regulated 1 2.003
TP63 tumor protein p63 2.003
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 1.924
GALK2 galactokinase 2 1.911
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.904
EVX2 even-skipped homeobox 2 1.846
HOXD13 homeobox D13 1.846
HOXD8 homeobox D8 1.846
HOXD9 homeobox D9 1.846
HOXD4 homeobox D4 1.846
HOXD10 homeobox D10 1.846
HOXD1 homeobox D1 1.846
MTX2 metaxin 2 1.846
HOXD3 homeobox D3 1.846
HOXD12 homeobox D12 1.846
HOXD11 homeobox D11 1.846
N4BP2L2 NEDD4 binding protein 2-like 2 1.837
N4BP2L1 NEDD4 binding protein 2-like 1 1.837
FRY furry homolog (Drosophila) 1.837
BRCA2 breast cancer 2, early onset 1.837
ZAR1L zygote arrest 1-like 1.837
IREB2 iron-responsive element binding protein 2 1.825
FOXP4 forkhead box P4 1.821
BTNL2 butyrophilin-like 2 1.776
TSBP1 testis expressed basic protein 1 1.776
HLA-DRA major histocompatibility complex, class II, DR alpha 1.776
COPS2 COP9 signalosome subunit 2 1.724
MORF4L1 mortality factor 4 like 1 1.707
LRRIQ4 leucine-rich repeats and IQ motif containing 4 1.68
MYNN myoneurin 1.68
LRRC31 leucine rich repeat containing 31 1.68
ACTRT3 actin-related protein T3 1.68
LRRC34 leucine rich repeat containing 34 1.68
CHEK2 checkpoint kinase 2 1.666
TTC28 tetratricopeptide repeat domain 28 1.666
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone 1.666
XBP1 X-box binding protein 1 1.666
CCDC117 coiled-coil domain containing 117 1.666
C17ORF58 chromosome 17 open reading frame 58 1.584
BPTF bromodomain PHD finger transcription factor 1.584
PSD4 pleckstrin and Sec7 domain containing 4 1.563
IL1RN interleukin 1 receptor antagonist 1.563
PAX8 paired box 8 1.563
COMP cartilage oligomeric matrix protein 1.529
CRTC1 CREB regulated transcription coactivator 1 1.529
CRLF1 cytokine receptor-like factor 1 1.529
TMEM59L transmembrane protein 59-like 1.529
KLHL26 kelch-like family member 26 1.529
PRRC2A proline-rich coiled-coil 2A 1.527
C6ORF47 chromosome 6 open reading frame 47 1.527
ABHD16A abhydrolase domain containing 16A 1.527
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 1.527
LY6G5B lymphocyte antigen 6 complex, locus G5B 1.527
GPANK1 G patch domain and ankyrin repeats 1 1.527
LTA lymphotoxin alpha 1.527
MSH5 mutS homolog 5 1.527
DDAH2 dimethylarginine dimethylaminohydrolase 2 1.527
LTB lymphotoxin beta (TNF superfamily, member 3) 1.527
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 1.527
LY6G6F lymphocyte antigen 6 complex, locus G6F 1.527
LY6G6C lymphocyte antigen 6 complex, locus G6C 1.527
CSNK2B casein kinase 2, beta polypeptide 1.527
LY6G5C lymphocyte antigen 6 complex, locus G5C 1.527
BAG6 BCL2-associated athanogene 6 1.527
TNF tumor necrosis factor 1.527
APOM apolipoprotein M 1.527
CLIC1 chloride intracellular channel 1 1.527
AIF1 allograft inflammatory factor 1 1.527
LY6G6D lymphocyte antigen 6 complex, locus G6D 1.527
NCR3 natural cytotoxicity triggering receptor 3 1.527
LST1 leukocyte specific transcript 1 1.527
FOXP1 forkhead box P1 1.523
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.522
MRPS22 mitochondrial ribosomal protein S22 1.517
PRR23C proline rich 23C 1.517
VTI1A vesicle transport through interaction with t-SNAREs 1A 1.515
MPZL3 myelin protein zero-like 3 1.509
SCN2B sodium channel, voltage gated, type II beta subunit 1.509
JAML junction adhesion molecule like 1.509
CD3E CD3e molecule, epsilon (CD3-TCR complex) 1.509
MPZL2 myelin protein zero-like 2 1.509
NRG1 neuregulin 1 1.444
ZDHHC11B zinc finger, DHHC-type containing 11B 1.425
TPPP tubulin polymerization promoting protein 1.425
CEP72 centrosomal protein 72kDa 1.425
FAM227B family with sequence similarity 227, member B 1.402
GDF7 growth differentiation factor 7 1.394
LDAH lipid droplet associated hydrolase 1.394
HS1BP3 HCLS1 binding protein 3 1.394
DTWD1 DTW domain containing 1 1.318
FGF7 fibroblast growth factor 7 1.303
SCN4B sodium channel, voltage gated, type IV beta subunit 1.294
BAZ1A bromodomain adjacent to zinc finger domain, 1A 1.294
IFNL1 interferon, lambda 1 1.252
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 1.252
GMFG glia maturation factor, gamma 1.252
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.252
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 1.252
IFNL2 interferon, lambda 2 1.252
IFNL3 interferon, lambda 3 1.252
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 1.252
MSRA methionine sulfoxide reductase A 1.252
SYCN syncollin 1.252
AQP9 aquaporin 9 1.252
NCCRP1 non-specific cytotoxic cell receptor protein 1 homolog (zebrafish) 1.252
CTTNBP2 cortactin binding protein 2 1.252
PTPDC1 protein tyrosine phosphatase domain containing 1 1.238
BARX1 BARX homeobox 1 1.238
DMRTA1 DMRT-like family A1 1.23
ACVRL1 activin A receptor type II-like 1 1.218
ACVR1B activin A receptor, type IB 1.218
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.218
ANKRD33 ankyrin repeat domain 33 1.218
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 1.216
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 1.189
HNF1B HNF1 homeobox B 1.189
GATA4 GATA binding protein 4 1.182
BLK BLK proto-oncogene, Src family tyrosine kinase 1.182
RALY RALY heterogeneous nuclear ribonucleoprotein 1.168
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 1.168
WNT2 wingless-type MMTV integration site family member 2 1.145
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 1.145
CD3D CD3d molecule, delta (CD3-TCR complex) 1.131
CD3G CD3g molecule, gamma (CD3-TCR complex) 1.131
AK5 adenylate kinase 5 1.131
HLA-DOA major histocompatibility complex, class II, DO alpha 1.121
COL11A2 collagen, type XI, alpha 2 1.121
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.121
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.121
OR14J1 olfactory receptor, family 14, subfamily J, member 1 1.104
MAS1L MAS1 proto-oncogene like, G protein-coupled receptor 1.104
OR5V1 olfactory receptor, family 5, subfamily V, member 1 1.104
OR11A1 olfactory receptor, family 11, subfamily A, member 1 1.104
OR2H1 olfactory receptor, family 2, subfamily H, member 1 1.104
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) 1.104
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 1.104
OR12D3 olfactory receptor, family 12, subfamily D, member 3 1.104
PKLR pyruvate kinase, liver and RBC 1.078
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 1.078
CLK2 CDC-like kinase 2 1.078
TRIM46 tripartite motif containing 46 1.078
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 1.078
EFNA1 ephrin-A1 1.078
MUC1 mucin 1, cell surface associated 1.078
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 1.078
THBS3 thrombospondin 3 1.078
KRTCAP2 keratinocyte associated protein 2 1.078
FDPS farnesyl diphosphate synthase 1.078
SCAMP3 secretory carrier membrane protein 3 1.078
MTX1 metaxin 1 1.078
EGLN2 egl-9 family hypoxia-inducible factor 2 1.06
MIA melanoma inhibitory activity 1.06
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 1.06
RAB4B RAB4B, member RAS oncogene family 1.06
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 1.06
SNRPA small nuclear ribonucleoprotein polypeptide A 1.06
MTAP methylthioadenosine phosphorylase 1.056
SPRED2 sprouty-related, EVH1 domain containing 2 1.043
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 1.043
TDRD7 tudor domain containing 7 1.032
NCBP1 nuclear cap binding protein subunit 1, 80kDa 1.032
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 1.032
TMOD1 tropomodulin 1 1.032
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1.03
CDKN2A cyclin-dependent kinase inhibitor 2A 1.03
CTSH cathepsin H 0.999
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.999
EGFR epidermal growth factor receptor 0.97
SECISBP2L SECIS binding protein 2-like 0.904
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.812
FUBP1 far upstream element (FUSE) binding protein 1 0.812
GIPC2 GIPC PDZ domain containing family, member 2 0.812
NEXN nexilin (F actin binding protein) 0.812
STN1 STN1 subunit of CST complex 0.593
SLK STE20-like kinase 0.593
SH3PXD2A SH3 and PX domains 2A 0.593
ASIP agouti signaling protein 0.576
AHCY adenosylhomocysteinase 0.576
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 0.571
DVL3 dishevelled segment polarity protein 3 0.571
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 0.571
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 0.571
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic 0.571
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 0.571
TRIM27 tripartite motif containing 27 0.559
AQP3 aquaporin 3 (Gill blood group) 0.542
NFX1 nuclear transcription factor, X-box binding 1 0.542
AQP7 aquaporin 7 0.542
NOL6 nucleolar protein 6 (RNA-associated) 0.542
GAP43 growth associated protein 43 0.529
ATP8B4 ATPase, class I, type 8B, member 4 0.512