| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenosine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.145728 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.106412 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.10589 |
| ANXA1 | annexin A1 | 0.100282 |
| MKI67 | marker of proliferation Ki-67 | 0.0914288 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0883313 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.084738 |
| YAP1 | Yes-associated protein 1 | 0.081809 |
| TPM3 | tropomyosin 3 | 0.0766393 |
| RRM2 | ribonucleotide reductase M2 | 0.0747654 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0687243 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0616245 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0604724 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0531495 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0523658 |
| JMJD1C | jumonji domain containing 1C | 0.0498721 |
| MMP12 | matrix metallopeptidase 12 | 0.0498499 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0496078 |
| ASPH | aspartate beta-hydroxylase | 0.0489152 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0484429 |
| RPL3 | ribosomal protein L3 | 0.0478978 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0473532 |
| RTN4 | reticulon 4 | 0.0472554 |
| AREG | amphiregulin | 0.0460488 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0455727 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0447454 |
| TMEM41B | transmembrane protein 41B | 0.0442117 |
| EGR1 | early growth response 1 | 0.0439219 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.043613 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0422669 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0422304 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0401242 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0400948 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0394205 |
| WWOX | WW domain containing oxidoreductase | 0.0389156 |
| LDHA | lactate dehydrogenase A | 0.0385653 |
| NEBL | nebulette | 0.0381229 |
| EHBP1 | EH domain binding protein 1 | 0.0378468 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0373334 |
| FAT1 | FAT atypical cadherin 1 | 0.0369849 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0367408 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0364202 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0339212 |
| HMGA2 | high mobility group AT-hook 2 | 0.0332143 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0331712 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0325571 |
| RPS12 | ribosomal protein S12 | 0.0319379 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0315803 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0315278 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0314417 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0312125 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0311314 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0307882 |
| RPS3 | ribosomal protein S3 | 0.0305928 |
| BRD2 | bromodomain containing 2 | 0.0305105 |
| VMP1 | vacuole membrane protein 1 | 0.0302439 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0301083 |
| ANK2 | ankyrin 2, neuronal | 0.0297441 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0297312 |
| PRELID2 | PRELI domain containing 2 | 0.0295896 |
| SET | SET nuclear proto-oncogene | 0.0295312 |
| BRD4 | bromodomain containing 4 | 0.0286212 |
| DST | dystonin | 0.0282595 |
| RPS18 | ribosomal protein S18 | 0.0282421 |
| CALR | calreticulin | 0.0280948 |
| TUBB6 | tubulin, beta 6 class V | 0.0275483 |
| NHSL1 | NHS-like 1 | 0.0271209 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.026774 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.026643 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0262331 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.025936 |
| PDGFC | platelet derived growth factor C | 0.025844 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.025496 |
| MAP1B | microtubule-associated protein 1B | 0.0254918 |
| PRKCE | protein kinase C, epsilon | 0.0254906 |
| HDGF | hepatoma-derived growth factor | 0.0252047 |
| PNN | pinin, desmosome associated protein | 0.0251751 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0251249 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0242213 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0241142 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0240719 |
| MSN | moesin | 0.0239314 |
| PKM | pyruvate kinase, muscle | 0.023681 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.023493 |
| ACTG1 | actin gamma 1 | 0.0233887 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0233165 |
| RNF213 | ring finger protein 213 | 0.0232816 |
| MTAP | methylthioadenosine phosphorylase | 0.0229841 |
| CCN2 | cellular communication network factor 2 | 0.0228773 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0227686 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0227429 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.022505 |
| GSE1 | Gse1 coiled-coil protein | 0.0222397 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0222204 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.022165 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0217573 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0217423 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0216712 |
| MSH6 | mutS homolog 6 | 0.0216243 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0215508 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.136564 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107392 |
| TMSB10 | thymosin beta 10 | -0.0970917 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0929643 |
| AHNAK | AHNAK nucleoprotein | -0.0771196 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0760792 |
| CLDN1 | claudin 1 | -0.0685102 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0654112 |
| RPS24 | ribosomal protein S24 | -0.0622765 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0571063 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0559679 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.055136 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0536854 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0530527 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0528655 |
| MGAT4C | MGAT4 family, member C | -0.0512719 |
| RPL35A | ribosomal protein L35a | -0.050321 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.050216 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0480574 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0472887 |
| RPLP1 | ribosomal protein, large, P1 | -0.0455316 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.044143 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0430549 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0427304 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0416467 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0412986 |
| CCND1 | cyclin D1 | -0.0411721 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0399994 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0393319 |
| RPS16 | ribosomal protein S16 | -0.038792 |
| TMEM123 | transmembrane protein 123 | -0.0378587 |
| LMO7 | LIM domain 7 | -0.0373293 |
| GNAS | GNAS complex locus | -0.0362218 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0359893 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0352697 |
| FBXO11 | F-box protein 11 | -0.034866 |
| RPL8 | ribosomal protein L8 | -0.0344371 |
| FTL | ferritin, light polypeptide | -0.0343302 |
| NF1 | neurofibromin 1 | -0.034198 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0340016 |
| RPL19 | ribosomal protein L19 | -0.0339973 |
| CDK6 | cyclin-dependent kinase 6 | -0.0337074 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0335601 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0328637 |
| PTMA | prothymosin, alpha | -0.0327199 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0324408 |
| RPL27A | ribosomal protein L27a | -0.0323145 |
| SYT1 | synaptotagmin I | -0.0321549 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.0319893 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0318263 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.031726 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0309383 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.030746 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0305381 |
| OXR1 | oxidation resistance 1 | -0.0305215 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0299647 |
| NEK7 | NIMA-related kinase 7 | -0.0295964 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0289138 |
| ZNF804A | zinc finger protein 804A | -0.0287657 |
| PCDH7 | protocadherin 7 | -0.028544 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.02818 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0281317 |
| WDR45B | WD repeat domain 45B | -0.0281088 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0278322 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0277911 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0276124 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0275729 |
| TMEM131 | transmembrane protein 131 | -0.0274695 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0274494 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0274318 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0273555 |
| NPR2 | natriuretic peptide receptor 2 | -0.0272998 |
| RPL32 | ribosomal protein L32 | -0.0269049 |
| RTN3 | reticulon 3 | -0.0267934 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0266689 |
| USP15 | ubiquitin specific peptidase 15 | -0.026579 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0262666 |
| BTG3 | BTG family, member 3 | -0.0262108 |
| RPS27A | ribosomal protein S27a | -0.0259843 |
| RPLP0 | ribosomal protein, large, P0 | -0.0258745 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0257073 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0254852 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0254817 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0254324 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0254264 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0252868 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0251222 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.025014 |
| RPL12 | ribosomal protein L12 | -0.0246619 |
| CD2AP | CD2-associated protein | -0.0246405 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0246358 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0245904 |
| CCNI | cyclin I | -0.0244524 |
| RLF | rearranged L-myc fusion | -0.0244188 |
| EDN1 | endothelin 1 | -0.0243294 |
| S100A6 | S100 calcium binding protein A6 | -0.0239981 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0239619 |
| HMGB2 | high mobility group box 2 | -0.0239104 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.023596 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0235118 |
