| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenosine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.385717 |
| COL6A3 | collagen, type VI, alpha 3 | 0.204572 |
| NDRG1 | N-myc downstream regulated 1 | 0.121236 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.114357 |
| LOXL2 | lysyl oxidase-like 2 | 0.0870152 |
| COL5A1 | collagen, type V, alpha 1 | 0.0818007 |
| PLEC | plectin | 0.0560627 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0492724 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0426503 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0406317 |
| NAV1 | neuron navigator 1 | 0.0370526 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0359812 |
| EGFR | epidermal growth factor receptor | 0.0310275 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0297602 |
| RUNX1 | runt-related transcription factor 1 | 0.029353 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0276579 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0266034 |
| TNS1 | tensin 1 | 0.0259384 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0255367 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0254548 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0251335 |
| NAV2 | neuron navigator 2 | 0.0248476 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0247467 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.023497 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0231222 |
| MSN | moesin | 0.0230477 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0229784 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0229702 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0214523 |
| CD44 | CD44 molecule (Indian blood group) | 0.0212583 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0206487 |
| FAT1 | FAT atypical cadherin 1 | 0.0206019 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0202218 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.018412 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0182661 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0181868 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0176614 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0173696 |
| SMAD3 | SMAD family member 3 | 0.0171015 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0169917 |
| MYO10 | myosin X | 0.0167382 |
| IL6 | interleukin 6 | 0.0164754 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0162256 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0161609 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0158423 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0157137 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0157059 |
| SDC2 | syndecan 2 | 0.0156394 |
| EFNA5 | ephrin-A5 | 0.0153865 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0152285 |
| FAM219A | family with sequence similarity 219, member A | 0.0147819 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0147496 |
| BRD2 | bromodomain containing 2 | 0.0147057 |
| ECE1 | endothelin converting enzyme 1 | 0.0145895 |
| STC1 | stanniocalcin 1 | 0.014238 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0141792 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0141563 |
| TRAM2 | translocation associated membrane protein 2 | 0.0141154 |
| GLIS3 | GLIS family zinc finger 3 | 0.0140054 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0139615 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0139075 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.01372 |
| RASA3 | RAS p21 protein activator 3 | 0.0136818 |
| SETBP1 | SET binding protein 1 | 0.0135674 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0135358 |
| PDE10A | phosphodiesterase 10A | 0.0133542 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0132605 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0130613 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0130144 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0127708 |
| CMIP | c-Maf inducing protein | 0.0126733 |
| SH3PXD2B | SH3 and PX domains 2B | 0.0124542 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0123922 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0123836 |
| HLA-B | major histocompatibility complex, class I, B | 0.0123788 |
| C1D | C1D nuclear receptor corepressor | 0.0122807 |
| FLNB | filamin B, beta | 0.01224 |
| YEATS2 | YEATS domain containing 2 | 0.0121904 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0120608 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0119824 |
| JAG1 | jagged 1 | 0.0119549 |
| CAPRIN2 | caprin family member 2 | 0.0119104 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0118981 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0116656 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0115854 |
| CEP250 | centrosomal protein 250kDa | 0.0115476 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0115474 |
| CST3 | cystatin C | 0.011409 |
| HAS2 | hyaluronan synthase 2 | 0.011064 |
| ANGPTL4 | angiopoietin-like 4 | 0.0110623 |
| CLMP | CXADR-like membrane protein | 0.0106659 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0106627 |
| APP | amyloid beta (A4) precursor protein | 0.0106385 |
| SKI | SKI proto-oncogene | 0.0105861 |
| PLXNA1 | plexin A1 | 0.0105184 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0105181 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0104431 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0104222 |
| ANXA6 | annexin A6 | 0.010408 |
| KIAA1217 | KIAA1217 | 0.0103739 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.255606 |
| VIM | vimentin | -0.215496 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145972 |
| COL1A1 | collagen, type I, alpha 1 | -0.145945 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.113088 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.110414 |
| FN1 | fibronectin 1 | -0.103011 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.098593 |
| COL1A2 | collagen, type I, alpha 2 | -0.091366 |
| CANX | calnexin | -0.0803406 |
| UBC | ubiquitin C | -0.0773195 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0768776 |
| CADM1 | cell adhesion molecule 1 | -0.0736597 |
| PTMA | prothymosin, alpha | -0.0730735 |
| ENO1 | enolase 1, (alpha) | -0.0688964 |
| FNDC3B | fibronectin type III domain containing 3B | -0.067841 |
| TMSB10 | thymosin beta 10 | -0.0675083 |
| AHNAK | AHNAK nucleoprotein | -0.0654415 |
| TPM4 | tropomyosin 4 | -0.0634684 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0608269 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.059249 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0558174 |
| POSTN | periostin, osteoblast specific factor | -0.0534884 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0525353 |
| IER3 | immediate early response 3 | -0.0514042 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0507616 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.050532 |
| CLIC4 | chloride intracellular channel 4 | -0.0500631 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0480049 |
| IL6ST | interleukin 6 signal transducer | -0.0468751 |
| FBN1 | fibrillin 1 | -0.0452722 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0434007 |
| RPL35A | ribosomal protein L35a | -0.042301 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0420067 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.040039 |
| FTL | ferritin, light polypeptide | -0.0397038 |
| RPS8 | ribosomal protein S8 | -0.0386261 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0375304 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0370693 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0365264 |
| TRAM1 | translocation associated membrane protein 1 | -0.0364062 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0336838 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0336657 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0333274 |
| PKM | pyruvate kinase, muscle | -0.0333134 |
| CALU | calumenin | -0.0330843 |
| LOX | lysyl oxidase | -0.0330509 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0327074 |
| QKI | QKI, KH domain containing, RNA binding | -0.0327074 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0313501 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0313422 |
| RPS6 | ribosomal protein S6 | -0.0310641 |
| SEPTIN7 | septin 7 | -0.0306145 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0305841 |
| RPL19 | ribosomal protein L19 | -0.0297828 |
| ANXA2 | annexin A2 | -0.0297449 |
| PGK1 | phosphoglycerate kinase 1 | -0.0296074 |
| BBX | bobby sox homolog (Drosophila) | -0.0293641 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0290782 |
| TMSB4X | thymosin beta 4, X-linked | -0.0289772 |
| PTK2 | protein tyrosine kinase 2 | -0.02888 |
| PALLD | palladin, cytoskeletal associated protein | -0.0287304 |
| ZNF292 | zinc finger protein 292 | -0.0286391 |
| YBX1 | Y box binding protein 1 | -0.0284177 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0280671 |
| RHEB | Ras homolog enriched in brain | -0.0279793 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0279434 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0277644 |
| SPAG9 | sperm associated antigen 9 | -0.0277065 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0276742 |
| TFG | TRK-fused gene | -0.0276524 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0275861 |
| RLF | rearranged L-myc fusion | -0.0273496 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0271848 |
| RPS24 | ribosomal protein S24 | -0.0270615 |
| RAB1A | RAB1A, member RAS oncogene family | -0.02703 |
| B2M | beta-2-microglobulin | -0.0268815 |
| S100A6 | S100 calcium binding protein A6 | -0.0267763 |
| RPL11 | ribosomal protein L11 | -0.0265318 |
| LDHA | lactate dehydrogenase A | -0.0262785 |
| RPS27A | ribosomal protein S27a | -0.0262077 |
| RPL12 | ribosomal protein L12 | -0.0261075 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0257698 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0255163 |
| USP3 | ubiquitin specific peptidase 3 | -0.0251176 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0250737 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0247406 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0244872 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0242829 |
| DSTN | destrin (actin depolymerizing factor) | -0.0242572 |
| RPL26 | ribosomal protein L26 | -0.0241933 |
| SDCBP | syndecan binding protein (syntenin) | -0.0241142 |
| RPL8 | ribosomal protein L8 | -0.0239964 |
| ATP13A3 | ATPase type 13A3 | -0.0237086 |
| S100A10 | S100 calcium binding protein A10 | -0.0233695 |
| POTEF | POTE ankyrin domain family, member F | -0.0233584 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0225413 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.022499 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0224687 |
| WASF2 | WAS protein family, member 2 | -0.0224633 |
