| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Adenosine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.178481 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.145577 |
| GRB10 | growth factor receptor-bound protein 10 | 0.091475 |
| SMAD3 | SMAD family member 3 | 0.0837513 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0773313 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0660597 |
| CD44 | CD44 molecule (Indian blood group) | 0.0553324 |
| NAV2 | neuron navigator 2 | 0.051579 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0507157 |
| LOXL2 | lysyl oxidase-like 2 | 0.0482719 |
| SIK3 | SIK family kinase 3 | 0.0443306 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0443166 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0440791 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0437611 |
| ECE1 | endothelin converting enzyme 1 | 0.0435371 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0413546 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0407047 |
| TGM2 | transglutaminase 2 | 0.0390349 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0380541 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0364346 |
| OPTN | optineurin | 0.035838 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0358031 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0354876 |
| RAD51B | RAD51 paralog B | 0.0352855 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0346492 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0327522 |
| ANGPTL4 | angiopoietin-like 4 | 0.0318556 |
| PFKP | phosphofructokinase, platelet | 0.0310278 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0308573 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0308184 |
| MLPH | melanophilin | 0.0305516 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0302721 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0299169 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0293488 |
| SYNJ2 | synaptojanin 2 | 0.0288674 |
| FHL2 | four and a half LIM domains 2 | 0.0280428 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0279028 |
| EZR | ezrin | 0.0276677 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0275286 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0274935 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0274705 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0274394 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0274131 |
| RUNX1 | runt-related transcription factor 1 | 0.0269442 |
| MAP1B | microtubule-associated protein 1B | 0.0268687 |
| NRP1 | neuropilin 1 | 0.026501 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0263195 |
| C1D | C1D nuclear receptor corepressor | 0.0263161 |
| MSN | moesin | 0.0260938 |
| VEGFC | vascular endothelial growth factor C | 0.0259587 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0259049 |
| WLS | wntless Wnt ligand secretion mediator | 0.0256017 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0253895 |
| NDRG1 | N-myc downstream regulated 1 | 0.0251793 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0249441 |
| FLNB | filamin B, beta | 0.024931 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0248864 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0245988 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0244243 |
| HAS2 | hyaluronan synthase 2 | 0.0239919 |
| EGR1 | early growth response 1 | 0.0239916 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0237399 |
| PODXL | podocalyxin-like | 0.02371 |
| CA12 | carbonic anhydrase XII | 0.0236725 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0236009 |
| CEP250 | centrosomal protein 250kDa | 0.023505 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0233595 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0232346 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0231016 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0230156 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0228906 |
| STRA6 | stimulated by retinoic acid 6 | 0.0227972 |
| TNS1 | tensin 1 | 0.0226736 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0225312 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0221893 |
| ITGAV | integrin, alpha V | 0.0219538 |
| KIAA1217 | KIAA1217 | 0.0218198 |
| HMGA1 | high mobility group AT-hook 1 | 0.0217648 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0216925 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0216862 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0214609 |
| RNF24 | ring finger protein 24 | 0.0213661 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0212318 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0212137 |
| ZNF469 | zinc finger protein 469 | 0.0209634 |
| SVIL | supervillin | 0.0209346 |
| NTN4 | netrin 4 | 0.0209229 |
| ACTN4 | actinin, alpha 4 | 0.0207896 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0207024 |
| SEPTIN9 | septin 9 | 0.020665 |
| FOSL1 | FOS-like antigen 1 | 0.020564 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0205184 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0203561 |
| STK38L | serine/threonine kinase 38 like | 0.0202462 |
| FAM13A | family with sequence similarity 13, member A | 0.0201456 |
| RPL36 | ribosomal protein L36 | 0.0200986 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0200749 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0200226 |
| MYO10 | myosin X | 0.019976 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0197917 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.222602 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.164739 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155122 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.133433 |
| NRG1 | neuregulin 1 | -0.125971 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.124103 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.11829 |
| CDH13 | cadherin 13 | -0.106864 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.101451 |
| LOX | lysyl oxidase | -0.0960843 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0749669 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0721301 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0720324 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0703164 |
| CANX | calnexin | -0.0700172 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0674964 |
| NCOA7 | nuclear receptor coactivator 7 | -0.066576 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0616908 |
| AHNAK | AHNAK nucleoprotein | -0.0602062 |
| MTSS1 | metastasis suppressor 1 | -0.0598573 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0586822 |
| USP34 | ubiquitin specific peptidase 34 | -0.0551818 |
| ZNF804A | zinc finger protein 804A | -0.0544273 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0531442 |
| GPC6 | glypican 6 | -0.0514799 |
| FN1 | fibronectin 1 | -0.0514636 |
| HMGA2 | high mobility group AT-hook 2 | -0.0507257 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.05067 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0494517 |
| FBN1 | fibrillin 1 | -0.049284 |
| HDLBP | high density lipoprotein binding protein | -0.0490668 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0485025 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0482263 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0473027 |
| UBC | ubiquitin C | -0.0470673 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0461786 |
| STC1 | stanniocalcin 1 | -0.0454861 |
| RBM39 | RNA binding motif protein 39 | -0.0453075 |
| FAM20C | family with sequence similarity 20, member C | -0.0451377 |
| DNER | delta/notch-like EGF repeat containing | -0.0440377 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0428812 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0423264 |
| CDK14 | cyclin-dependent kinase 14 | -0.0422307 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0421595 |
| GOLGA4 | golgin A4 | -0.0421419 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0408046 |
| ASPH | aspartate beta-hydroxylase | -0.0399419 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0393547 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0389102 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0387878 |
| EREG | epiregulin | -0.0387592 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0385189 |
| NLK | nemo-like kinase | -0.0384277 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0383351 |
| SP100 | SP100 nuclear antigen | -0.037654 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0372383 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0372072 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0368961 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0354623 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0351437 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0343555 |
| TMEM263 | transmembrane protein 263 | -0.034319 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.034058 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0339298 |
| ATG7 | autophagy related 7 | -0.0336303 |
| NUMB | numb homolog (Drosophila) | -0.0333077 |
| PTMA | prothymosin, alpha | -0.0332625 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0331815 |
| NF1 | neurofibromin 1 | -0.0331426 |
| AADAC | arylacetamide deacetylase | -0.0330821 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0328215 |
| PHF3 | PHD finger protein 3 | -0.0325688 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0322206 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0321992 |
| RPS24 | ribosomal protein S24 | -0.0320399 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0320344 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0319514 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0319119 |
| VCL | vinculin | -0.0313707 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0313103 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0311758 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0311325 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0310994 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0310973 |
| IER3 | immediate early response 3 | -0.030454 |
| ENO1 | enolase 1, (alpha) | -0.030437 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0303756 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0302838 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0300229 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0299565 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0299191 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0297545 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0295442 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0294655 |
| GLCCI1 | glucocorticoid induced 1 | -0.0293975 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0292826 |
| DIAPH2 | diaphanous-related formin 2 | -0.0292312 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0291495 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0290374 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0290123 |