| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Adenosine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.317982 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.178962 |
| GRAMD1B | GRAM domain containing 1B | 0.167813 |
| IGF2 | insulin-like growth factor 2 | 0.155173 |
| MT2A | metallothionein 2A | 0.128871 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.09775 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0933037 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0812514 |
| FLNB | filamin B, beta | 0.0750233 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0739323 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0691115 |
| LDHA | lactate dehydrogenase A | 0.0688177 |
| IL6 | interleukin 6 | 0.0602564 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0592113 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.056653 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0522142 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0521841 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0508081 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0484294 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0483365 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0462365 |
| VEGFA | vascular endothelial growth factor A | 0.0457943 |
| EGFR | epidermal growth factor receptor | 0.0448607 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0445008 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0439609 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0435288 |
| MATR3 | matrin 3 | 0.0435232 |
| CMIP | c-Maf inducing protein | 0.0432908 |
| PFKP | phosphofructokinase, platelet | 0.0431328 |
| ANGPTL4 | angiopoietin-like 4 | 0.0413978 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0411509 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0397698 |
| ITGB5 | integrin, beta 5 | 0.0363475 |
| HLA-A | major histocompatibility complex, class I, A | 0.035726 |
| FGA | fibrinogen alpha chain | 0.0350593 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.035043 |
| APP | amyloid beta (A4) precursor protein | 0.0348448 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0346139 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0345311 |
| RPS3 | ribosomal protein S3 | 0.0339481 |
| TCIM | transcriptional and immune response regulator | 0.0337542 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0336069 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0330724 |
| HLA-B | major histocompatibility complex, class I, B | 0.0329619 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0329439 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.032252 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0322339 |
| ANXA1 | annexin A1 | 0.0322276 |
| LAMB1 | laminin, beta 1 | 0.0316874 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0312306 |
| SVIL | supervillin | 0.0311432 |
| LAMC2 | laminin, gamma 2 | 0.0310674 |
| SFTPA2 | surfactant protein A2 | 0.030941 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0303015 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0301515 |
| STC1 | stanniocalcin 1 | 0.0299434 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.029572 |
| PLEC | plectin | 0.0292549 |
| RPL3 | ribosomal protein L3 | 0.0291753 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0290117 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0281661 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0278901 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0277422 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0274186 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0273397 |
| MSN | moesin | 0.0272027 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0265697 |
| RPS18 | ribosomal protein S18 | 0.0265569 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0262966 |
| OPTN | optineurin | 0.0260821 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0260748 |
| ATP11A | ATPase, class VI, type 11A | 0.0258725 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0258262 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0255424 |
| ATXN1 | ataxin 1 | 0.0251545 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0250448 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0249485 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0248504 |
| TMEM14C | transmembrane protein 14C | 0.0248294 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0248172 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0247923 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0247692 |
| TXNRD1 | thioredoxin reductase 1 | 0.0244256 |
| DNMBP | dynamin binding protein | 0.0243632 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.0242647 |
| CLU | clusterin | 0.0241918 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0237617 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0236145 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0233752 |
| ZFHX3 | zinc finger homeobox 3 | 0.0231218 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0230855 |
| CD44 | CD44 molecule (Indian blood group) | 0.0230774 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0229902 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0227332 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0227224 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0225142 |
| FAT1 | FAT atypical cadherin 1 | 0.022463 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0223282 |
| PHF21A | PHD finger protein 21A | 0.022273 |
| KLF6 | Kruppel-like factor 6 | 0.0220362 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.138463 |
| VIM | vimentin | -0.116695 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.108526 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.107927 |
| PTMA | prothymosin, alpha | -0.0799321 |
| POTEF | POTE ankyrin domain family, member F | -0.0763893 |
| RPL19 | ribosomal protein L19 | -0.0722019 |
| IER3 | immediate early response 3 | -0.0707361 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0690212 |
| RPS25 | ribosomal protein S25 | -0.066536 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0661141 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0654511 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.062038 |
| DENND4A | DENN/MADD domain containing 4A | -0.0618624 |
| RPL35A | ribosomal protein L35a | -0.0617704 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0606049 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.060583 |
| FTL | ferritin, light polypeptide | -0.0572055 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0551818 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0541254 |
| S100A6 | S100 calcium binding protein A6 | -0.0534514 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0499915 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0495858 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0480674 |
| RPS24 | ribosomal protein S24 | -0.047484 |
| ZNF207 | zinc finger protein 207 | -0.0470689 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0465087 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0457031 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0444358 |
| S100A10 | S100 calcium binding protein A10 | -0.0441837 |
| RHEB | Ras homolog enriched in brain | -0.0431153 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0422597 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0411094 |
| PTK2 | protein tyrosine kinase 2 | -0.0409711 |
| SMAD2 | SMAD family member 2 | -0.0409588 |
| RPS23 | ribosomal protein S23 | -0.0395069 |
| GNAS | GNAS complex locus | -0.0390984 |
| USP3 | ubiquitin specific peptidase 3 | -0.0380697 |
| RBM39 | RNA binding motif protein 39 | -0.0379455 |
| USP34 | ubiquitin specific peptidase 34 | -0.0369783 |
| RPS16 | ribosomal protein S16 | -0.0368518 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0365039 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0363874 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0358629 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0344574 |
| FBXO11 | F-box protein 11 | -0.0342982 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0342139 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0341782 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0339636 |
| TFG | TRK-fused gene | -0.0337684 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0334085 |
| RPL7 | ribosomal protein L7 | -0.0333593 |
| TPM4 | tropomyosin 4 | -0.0327205 |
| RPS2 | ribosomal protein S2 | -0.0324674 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0322781 |
| VCL | vinculin | -0.0318751 |
| RPS8 | ribosomal protein S8 | -0.0316882 |
| NOP58 | NOP58 ribonucleoprotein | -0.0314382 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0312382 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312301 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0308739 |
| SPAG9 | sperm associated antigen 9 | -0.0306357 |
| MIS18BP1 | MIS18 binding protein 1 | -0.030546 |
| HMGA1 | high mobility group AT-hook 1 | -0.030297 |
| MORF4L2 | mortality factor 4 like 2 | -0.0299729 |
| CANX | calnexin | -0.0296808 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0293348 |
| WDR43 | WD repeat domain 43 | -0.0291958 |
| AHNAK | AHNAK nucleoprotein | -0.0289372 |
| GOLT1B | golgi transport 1B | -0.0288182 |
| ASPH | aspartate beta-hydroxylase | -0.0288012 |
| RHOA | ras homolog family member A | -0.0287303 |
| PKM | pyruvate kinase, muscle | -0.0286428 |
| PCBP2 | poly(rC) binding protein 2 | -0.0283252 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0281541 |
| RPL37 | ribosomal protein L37 | -0.0280482 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0275587 |
| PARD3 | par-3 family cell polarity regulator | -0.027465 |
| ACTG1 | actin gamma 1 | -0.0270635 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0268712 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0265055 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.026396 |
| EGR1 | early growth response 1 | -0.0258259 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0257186 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.025431 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0252294 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0251903 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0251087 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0250611 |
| RPL5 | ribosomal protein L5 | -0.0249785 |
| NABP1 | nucleic acid binding protein 1 | -0.0249638 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0249026 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | -0.024866 |
| DSCAM | Down syndrome cell adhesion molecule | -0.024825 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0248073 |
| RPS27A | ribosomal protein S27a | -0.0247452 |
| CCNL1 | cyclin L1 | -0.0247085 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0246521 |
| PAPOLA | poly(A) polymerase alpha | -0.0246077 |
| SETD5 | SET domain containing 5 | -0.024597 |
