| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenosine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.203514 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.15803 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.142329 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.133845 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.124348 |
| NDRG1 | N-myc downstream regulated 1 | 0.101697 |
| LAMB3 | laminin, beta 3 | 0.100509 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0970228 |
| VEGFA | vascular endothelial growth factor A | 0.0906231 |
| ANXA2 | annexin A2 | 0.086745 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0846557 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0845942 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0789849 |
| VCL | vinculin | 0.0784967 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0765194 |
| TAOK1 | TAO kinase 1 | 0.0752269 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0750454 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0740392 |
| FRY | furry homolog (Drosophila) | 0.073554 |
| FN1 | fibronectin 1 | 0.0689007 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0685888 |
| TXNRD1 | thioredoxin reductase 1 | 0.0684327 |
| PRELID2 | PRELI domain containing 2 | 0.0672261 |
| RBM15 | RNA binding motif protein 15 | 0.0648453 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0644314 |
| MYO1E | myosin IE | 0.0641285 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0635242 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0627699 |
| ARRDC3 | arrestin domain containing 3 | 0.0627591 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0617412 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0607459 |
| ATP11A | ATPase, class VI, type 11A | 0.0605275 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0602315 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0600733 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0597252 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0578809 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.057234 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0570737 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.056977 |
| TOP1 | topoisomerase (DNA) I | 0.0558958 |
| FOXP1 | forkhead box P1 | 0.0544331 |
| STC1 | stanniocalcin 1 | 0.0541468 |
| NF1 | neurofibromin 1 | 0.0536075 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0531597 |
| VMP1 | vacuole membrane protein 1 | 0.0527533 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0521558 |
| OGA | O-GlcNAcase | 0.0521034 |
| EZR | ezrin | 0.0520631 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0507418 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0506601 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0497358 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0492523 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0488267 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0483244 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0479709 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0477594 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.047624 |
| VGLL4 | vestigial-like family member 4 | 0.0471619 |
| KRT17 | keratin 17, type I | 0.0468608 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0462877 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0459641 |
| FOXO3 | forkhead box O3 | 0.0456937 |
| TJP1 | tight junction protein 1 | 0.0454412 |
| DTNA | dystrobrevin, alpha | 0.0453532 |
| SEC24B | SEC24 family member B | 0.0442947 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0441515 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0440866 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0437535 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.042846 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0421583 |
| LAMA4 | laminin, alpha 4 | 0.0416841 |
| PKM | pyruvate kinase, muscle | 0.0412959 |
| BPTF | bromodomain PHD finger transcription factor | 0.0412719 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0411778 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0408309 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0405605 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0403942 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0401624 |
| CTBP2 | C-terminal binding protein 2 | 0.0400069 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | 0.0392908 |
| MYO5B | myosin VB | 0.039049 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0388895 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0386025 |
| CEP350 | centrosomal protein 350kDa | 0.0385926 |
| TXNIP | thioredoxin interacting protein | 0.038284 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0379835 |
| DUSP10 | dual specificity phosphatase 10 | 0.0379477 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0375641 |
| ENO1 | enolase 1, (alpha) | 0.0374877 |
| ITSN2 | intersectin 2 | 0.0373104 |
| ABHD17C | abhydrolase domain containing 17C | 0.0372001 |
| SLK | STE20-like kinase | 0.0369021 |
| ATXN1 | ataxin 1 | 0.0366964 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0365115 |
| CREBRF | CREB3 regulatory factor | 0.0364571 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0364536 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0364041 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0359606 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0359388 |
| RPL23 | ribosomal protein L23 | 0.0358189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.114698 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0980699 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0945463 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0891537 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0839272 |
| GRB10 | growth factor receptor-bound protein 10 | -0.083463 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.078701 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0779824 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.076653 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0742494 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0740155 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0706026 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0690542 |
| SPAG9 | sperm associated antigen 9 | -0.0673856 |
| RBM47 | RNA binding motif protein 47 | -0.0672786 |
| INTS6 | integrator complex subunit 6 | -0.0670785 |
| ATP13A3 | ATPase type 13A3 | -0.0649072 |
| CNKSR3 | CNKSR family member 3 | -0.064738 |
| MUC16 | mucin 16, cell surface associated | -0.0633308 |
| PTMA | prothymosin, alpha | -0.0631591 |
| RPL37A | ribosomal protein L37a | -0.063125 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0629713 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.062266 |
| TPM4 | tropomyosin 4 | -0.0617651 |
| RCOR1 | REST corepressor 1 | -0.0612112 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0599159 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0575763 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0575651 |
| EFNA5 | ephrin-A5 | -0.0564532 |
| MAP4 | microtubule-associated protein 4 | -0.0559673 |
| ZNF638 | zinc finger protein 638 | -0.0557183 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0553994 |
| HOMER1 | homer scaffolding protein 1 | -0.0551906 |
| GNAS | GNAS complex locus | -0.0549421 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0546792 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0535146 |
| LAMC2 | laminin, gamma 2 | -0.0529283 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0522854 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0517066 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0509478 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0506291 |
| ASPH | aspartate beta-hydroxylase | -0.0505636 |
| GLIS3 | GLIS family zinc finger 3 | -0.0501581 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0500695 |
| EXOC6B | exocyst complex component 6B | -0.049496 |
| SCEL | sciellin | -0.0493869 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0488308 |
| MMP1 | matrix metallopeptidase 1 | -0.0487461 |
| KIF13B | kinesin family member 13B | -0.048473 |
| RPS20 | ribosomal protein S20 | -0.0481987 |
| HLA-B | major histocompatibility complex, class I, B | -0.0478853 |
| GOLGA4 | golgin A4 | -0.0475532 |
| MEF2A | myocyte enhancer factor 2A | -0.0467682 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0466766 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0463881 |
| RTN4 | reticulon 4 | -0.0463383 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0453644 |
| CD44 | CD44 molecule (Indian blood group) | -0.0453207 |
| UBC | ubiquitin C | -0.0451671 |
| ZNF207 | zinc finger protein 207 | -0.0450792 |
| PARD3 | par-3 family cell polarity regulator | -0.0442919 |
| SBF2 | SET binding factor 2 | -0.044082 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0435713 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0433757 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0431781 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0429332 |
| SSH2 | slingshot protein phosphatase 2 | -0.0426091 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.042469 |
| HLA-A | major histocompatibility complex, class I, A | -0.042062 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0419899 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0419118 |
| CUX1 | cut-like homeobox 1 | -0.041739 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0407615 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0405693 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0404481 |
| AHNAK | AHNAK nucleoprotein | -0.0402068 |
| CDK13 | cyclin-dependent kinase 13 | -0.0401807 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0396473 |
| CLINT1 | clathrin interactor 1 | -0.0393686 |
| CD46 | CD46 molecule, complement regulatory protein | -0.039236 |
| MXD1 | MAX dimerization protein 1 | -0.0390747 |
| MORF4L2 | mortality factor 4 like 2 | -0.0387724 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0378626 |
| AK1 | adenylate kinase 1 | -0.0377338 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0371406 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0369982 |
| WASF2 | WAS protein family, member 2 | -0.0365763 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0364266 |
| FBXO11 | F-box protein 11 | -0.0354035 |
| SLMAP | sarcolemma associated protein | -0.0352105 |
| EHBP1 | EH domain binding protein 1 | -0.0350829 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.03489 |
| RPL37 | ribosomal protein L37 | -0.03487 |
| TMSB10 | thymosin beta 10 | -0.0346251 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0345652 |
| CDH13 | cadherin 13 | -0.0344708 |
| DENND4A | DENN/MADD domain containing 4A | -0.0343243 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.03422 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0341885 |
| ATF6 | activating transcription factor 6 | -0.0340349 |
