| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Adenosine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.242116 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.132304 |
| TXNRD1 | thioredoxin reductase 1 | 0.0893245 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0855032 |
| YBX3 | Y box binding protein 3 | 0.0770213 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0725884 |
| GRAMD1B | GRAM domain containing 1B | 0.0720044 |
| TPM3 | tropomyosin 3 | 0.0642773 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0568247 |
| POTEF | POTE ankyrin domain family, member F | 0.0558789 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0555689 |
| TPI1 | triosephosphate isomerase 1 | 0.0534175 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0531294 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0500938 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0471401 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0457761 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0445751 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0430754 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0425247 |
| BRD2 | bromodomain containing 2 | 0.0396381 |
| ATP11A | ATPase, class VI, type 11A | 0.0390386 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0383436 |
| KRT18 | keratin 18, type I | 0.0376131 |
| CDK17 | cyclin-dependent kinase 17 | 0.0373228 |
| CCNL1 | cyclin L1 | 0.0370706 |
| EGR1 | early growth response 1 | 0.0370392 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0363777 |
| MT2A | metallothionein 2A | 0.0343744 |
| PFN1 | profilin 1 | 0.0342747 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0342494 |
| STC1 | stanniocalcin 1 | 0.0333301 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0324158 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0318309 |
| MEF2D | myocyte enhancer factor 2D | 0.0311469 |
| WWOX | WW domain containing oxidoreductase | 0.0309031 |
| PNN | pinin, desmosome associated protein | 0.0308264 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0307398 |
| LATS2 | large tumor suppressor kinase 2 | 0.0302852 |
| RRM2 | ribonucleotide reductase M2 | 0.0302785 |
| VMP1 | vacuole membrane protein 1 | 0.0300787 |
| ACTN1 | actinin, alpha 1 | 0.0291426 |
| UBAP2L | ubiquitin associated protein 2-like | 0.028789 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0286577 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0283038 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0281843 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0279158 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0277492 |
| CTTN | cortactin | 0.0275116 |
| SET | SET nuclear proto-oncogene | 0.0274031 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0270308 |
| FLNA | filamin A, alpha | 0.0269229 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0269154 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0266876 |
| PDE10A | phosphodiesterase 10A | 0.0264621 |
| ANXA5 | annexin A5 | 0.0263621 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0261134 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0260628 |
| RPL3 | ribosomal protein L3 | 0.0260244 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0258288 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025571 |
| CALD1 | caldesmon 1 | 0.0255457 |
| MSN | moesin | 0.0255102 |
| LDHA | lactate dehydrogenase A | 0.0255 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0253796 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0252984 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.025113 |
| MSH6 | mutS homolog 6 | 0.0249078 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0248728 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0247112 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0244463 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0243071 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0240874 |
| DNMBP | dynamin binding protein | 0.023907 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0237582 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0237095 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0235848 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0235784 |
| SNX9 | sorting nexin 9 | 0.0235627 |
| RNF145 | ring finger protein 145 | 0.0234242 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0232294 |
| TLN1 | talin 1 | 0.0231251 |
| YBX1 | Y box binding protein 1 | 0.0230477 |
| CEP250 | centrosomal protein 250kDa | 0.0222387 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0221828 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0220844 |
| IL6ST | interleukin 6 signal transducer | 0.0219949 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0219946 |
| TBK1 | TANK-binding kinase 1 | 0.0218915 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0217527 |
| FUS | FUS RNA binding protein | 0.0216784 |
| RBM25 | RNA binding motif protein 25 | 0.0215118 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0213546 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0212832 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0210988 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0210957 |
| LUZP1 | leucine zipper protein 1 | 0.0210609 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0207514 |
| ATP13A3 | ATPase type 13A3 | 0.0206003 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0205074 |
| FOXM1 | forkhead box M1 | 0.0203784 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.159957 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0945872 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0887884 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0781971 |
| RPL37 | ribosomal protein L37 | -0.0707725 |
| RPL35A | ribosomal protein L35a | -0.0689749 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0626951 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0617858 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0617553 |
| AHNAK | AHNAK nucleoprotein | -0.0544754 |
| CANX | calnexin | -0.0532663 |
| PTMA | prothymosin, alpha | -0.0510404 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0499449 |
| GOLGB1 | golgin B1 | -0.0492129 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0460418 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0447699 |
| USP34 | ubiquitin specific peptidase 34 | -0.0446227 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439605 |
| VIM | vimentin | -0.0431763 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0427502 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0423879 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0414624 |
| FBXO11 | F-box protein 11 | -0.040893 |
| RAB10 | RAB10, member RAS oncogene family | -0.0381294 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.035707 |
| GNAS | GNAS complex locus | -0.0355211 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0352699 |
| RSF1 | remodeling and spacing factor 1 | -0.0344957 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0339733 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0333714 |
| AEBP2 | AE binding protein 2 | -0.0332945 |
| SRP72 | signal recognition particle 72kDa | -0.0332749 |
| HMGA2 | high mobility group AT-hook 2 | -0.0329125 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0324973 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0320835 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0317357 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0316852 |
| RPS8 | ribosomal protein S8 | -0.0315805 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0313606 |
| BBX | bobby sox homolog (Drosophila) | -0.0312986 |
| RPL32 | ribosomal protein L32 | -0.0312255 |
| RPS24 | ribosomal protein S24 | -0.0308266 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0307704 |
| RPL37A | ribosomal protein L37a | -0.0307538 |
| RPS27A | ribosomal protein S27a | -0.0301198 |
| RPS29 | ribosomal protein S29 | -0.0294728 |
| RPL26 | ribosomal protein L26 | -0.0294463 |
| ZNF609 | zinc finger protein 609 | -0.0294136 |
| NBEAL1 | neurobeachin-like 1 | -0.0292783 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0292094 |
| RPS25 | ribosomal protein S25 | -0.0291762 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0290237 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0288524 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0284977 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0284809 |
| CDK13 | cyclin-dependent kinase 13 | -0.0282282 |
| MAP4 | microtubule-associated protein 4 | -0.0282134 |
| UBE3C | ubiquitin protein ligase E3C | -0.0279416 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0278413 |
| RPL38 | ribosomal protein L38 | -0.027698 |
| RYR3 | ryanodine receptor 3 | -0.0273667 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0269874 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0264716 |
| INTS6 | integrator complex subunit 6 | -0.0262319 |
| RPS15 | ribosomal protein S15 | -0.0261015 |
| S100A10 | S100 calcium binding protein A10 | -0.0258619 |
| GOLGA4 | golgin A4 | -0.0255695 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0250363 |
| EHBP1 | EH domain binding protein 1 | -0.0249672 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0248952 |
| GPATCH2L | G patch domain containing 2-like | -0.0248214 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0242781 |
| LMAN1 | lectin, mannose-binding, 1 | -0.024235 |
| ZBTB1 | zinc finger and BTB domain containing 1 | -0.0241714 |
| HLA-B | major histocompatibility complex, class I, B | -0.0240283 |
| PYGL | phosphorylase, glycogen, liver | -0.0239698 |
| RPL31 | ribosomal protein L31 | -0.0239133 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0238326 |
| RPLP1 | ribosomal protein, large, P1 | -0.0237323 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0236596 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0235525 |
| LRRC23 | leucine rich repeat containing 23 | -0.0235154 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0231846 |
| RPS16 | ribosomal protein S16 | -0.0230947 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0229926 |
| RPL30 | ribosomal protein L30 | -0.0228492 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.022769 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0225388 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0225105 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0223944 |
| DENND5B | DENN/MADD domain containing 5B | -0.02237 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.022349 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0222509 |
| HLA-E | major histocompatibility complex, class I, E | -0.0221855 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0216896 |
| TAOK1 | TAO kinase 1 | -0.02155 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0214967 |
| TFCP2 | transcription factor CP2 | -0.0212535 |
| GOLGA3 | golgin A3 | -0.0210791 |
| KIAA1328 | KIAA1328 | -0.0210113 |