| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenosine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.252854 |
| LAMB3 | laminin, beta 3 | 0.101204 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.098513 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0956248 |
| NDRG1 | N-myc downstream regulated 1 | 0.0888894 |
| PLEC | plectin | 0.0875574 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0694653 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0621647 |
| CLDN4 | claudin 4 | 0.0599803 |
| ACTG1 | actin gamma 1 | 0.0599447 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0583045 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0564368 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0555133 |
| LAMC2 | laminin, gamma 2 | 0.0547351 |
| MSN | moesin | 0.054008 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0507868 |
| RBM25 | RNA binding motif protein 25 | 0.0503521 |
| RPS3 | ribosomal protein S3 | 0.0488618 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0467383 |
| TMF1 | TATA element modulatory factor 1 | 0.045912 |
| JUP | junction plakoglobin | 0.0457087 |
| ARRDC3 | arrestin domain containing 3 | 0.0453476 |
| BRD2 | bromodomain containing 2 | 0.0428448 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0419735 |
| CTSB | cathepsin B | 0.040159 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0397093 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0391551 |
| CD44 | CD44 molecule (Indian blood group) | 0.039097 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0388206 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0381719 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0362741 |
| YTHDC1 | YTH domain containing 1 | 0.0352613 |
| HLA-B | major histocompatibility complex, class I, B | 0.0343965 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0342414 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0337535 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0333132 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0331275 |
| FLNB | filamin B, beta | 0.0320215 |
| TPM3 | tropomyosin 3 | 0.03182 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0317824 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0316929 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.03107 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0309474 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0294762 |
| EZR | ezrin | 0.0293703 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0292471 |
| ANXA1 | annexin A1 | 0.0290215 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0286844 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0284715 |
| GOLGA4 | golgin A4 | 0.0284436 |
| CALR | calreticulin | 0.0283865 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0278164 |
| RPS18 | ribosomal protein S18 | 0.0277692 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0274784 |
| FLNA | filamin A, alpha | 0.027186 |
| MYO5B | myosin VB | 0.0270926 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0270903 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0264585 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0264464 |
| RPL3 | ribosomal protein L3 | 0.0259432 |
| SMAD3 | SMAD family member 3 | 0.0256788 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0254443 |
| DUSP10 | dual specificity phosphatase 10 | 0.0253705 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0253663 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0250872 |
| OPTN | optineurin | 0.0248183 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0247382 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0243457 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0238259 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0236002 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0234768 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.023414 |
| FUS | FUS RNA binding protein | 0.0231692 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0230445 |
| IER5 | immediate early response 5 | 0.0226884 |
| TXNIP | thioredoxin interacting protein | 0.0226075 |
| BCL2L1 | BCL2-like 1 | 0.0223205 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0222669 |
| MYO10 | myosin X | 0.022184 |
| TPR | translocated promoter region, nuclear basket protein | 0.0218762 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0218192 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0217087 |
| AFDN | afadin, adherens junction formation factor | 0.0216046 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0214065 |
| RPS12 | ribosomal protein S12 | 0.0213923 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0211348 |
| VGLL3 | vestigial-like family member 3 | 0.0209494 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0208338 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | 0.0208034 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0205585 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0204872 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0204539 |
| CTTN | cortactin | 0.0202912 |
| JUN | jun proto-oncogene | 0.020208 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0201264 |
| MYO1E | myosin IE | 0.0200964 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0199566 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0199015 |
| ADM | adrenomedullin | 0.0197409 |
| EGR1 | early growth response 1 | 0.0196965 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.260324 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.223658 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.166414 |
| ASPH | aspartate beta-hydroxylase | -0.112707 |
| S100A6 | S100 calcium binding protein A6 | -0.098085 |
| POTEF | POTE ankyrin domain family, member F | -0.0799633 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0799136 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0745262 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0703863 |
| S100A10 | S100 calcium binding protein A10 | -0.0702045 |
| TOP1 | topoisomerase (DNA) I | -0.0678662 |
| RPL35A | ribosomal protein L35a | -0.0666934 |
| TMSB10 | thymosin beta 10 | -0.0645593 |
| AHNAK | AHNAK nucleoprotein | -0.0631752 |
| HMGA1 | high mobility group AT-hook 1 | -0.0629087 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0625008 |
| UBC | ubiquitin C | -0.0607864 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0603988 |
| PGK1 | phosphoglycerate kinase 1 | -0.0574066 |
| TMEM123 | transmembrane protein 123 | -0.0572098 |
| CANX | calnexin | -0.0570927 |
| ANXA2 | annexin A2 | -0.0552947 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0514156 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0514045 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0505605 |
| CD2AP | CD2-associated protein | -0.0503232 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0487195 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.047994 |
| GNAS | GNAS complex locus | -0.0473993 |
| CCND1 | cyclin D1 | -0.0469355 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0467572 |
| TKT | transketolase | -0.0450723 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0443387 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0438924 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0429342 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0426781 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.042658 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0425546 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0423006 |
| RPLP1 | ribosomal protein, large, P1 | -0.0419418 |
| RPLP0 | ribosomal protein, large, P0 | -0.0417491 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0412845 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0408269 |
| RPS23 | ribosomal protein S23 | -0.0404053 |
| SP100 | SP100 nuclear antigen | -0.039477 |
| HMGB2 | high mobility group box 2 | -0.0391593 |
| RPS24 | ribosomal protein S24 | -0.0391418 |
| RPL32 | ribosomal protein L32 | -0.038144 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0375298 |
| RHEB | Ras homolog enriched in brain | -0.0373197 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0372988 |
| USP3 | ubiquitin specific peptidase 3 | -0.0369367 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0369077 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0367561 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0366098 |
| RPS25 | ribosomal protein S25 | -0.0364906 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0357213 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.035652 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0350121 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0344989 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0344541 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0344427 |
| RPL27A | ribosomal protein L27a | -0.0336811 |
| ENO1 | enolase 1, (alpha) | -0.0333615 |
| RPL8 | ribosomal protein L8 | -0.0328533 |
| FN1 | fibronectin 1 | -0.0324909 |
| KRT7 | keratin 7, type II | -0.0324011 |
| PTMA | prothymosin, alpha | -0.0323594 |
| PDLIM5 | PDZ and LIM domain 5 | -0.032329 |
| RPL19 | ribosomal protein L19 | -0.031908 |
| TUBA1B | tubulin, alpha 1b | -0.0312589 |
| ARF1 | ADP-ribosylation factor 1 | -0.0311898 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0311307 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0310307 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0306857 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0305711 |
| VCL | vinculin | -0.0303775 |
| CCNI | cyclin I | -0.0302248 |
| VIM | vimentin | -0.0300937 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0297524 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0297226 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0297216 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0295522 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0295447 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.029391 |
| STEAP4 | STEAP family member 4 | -0.0293093 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0293033 |
| RPS5 | ribosomal protein S5 | -0.0288451 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0287418 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0284436 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0283241 |
| RHOA | ras homolog family member A | -0.028298 |
| VDAC1 | voltage-dependent anion channel 1 | -0.028238 |
| DEK | DEK proto-oncogene | -0.0280723 |
| PLAU | plasminogen activator, urokinase | -0.0278016 |
| TXNRD1 | thioredoxin reductase 1 | -0.0277722 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.027755 |
| TRAM1 | translocation associated membrane protein 1 | -0.0276181 |
| RPS16 | ribosomal protein S16 | -0.0273197 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.027045 |
