| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenosine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.135684 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.121004 |
| GRAMD1B | GRAM domain containing 1B | 0.097714 |
| PDE10A | phosphodiesterase 10A | 0.0957306 |
| DST | dystonin | 0.0956658 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0837911 |
| FN1 | fibronectin 1 | 0.0826842 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0806243 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0773924 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0696522 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0692851 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0600525 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0595122 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0589586 |
| GDA | guanine deaminase | 0.0583437 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.056657 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.054143 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0531205 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0487527 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0483951 |
| CD109 | CD109 molecule | 0.0470252 |
| COL5A2 | collagen, type V, alpha 2 | 0.0470029 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0461234 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0460616 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0458317 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0453017 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.045001 |
| PCBP3 | poly(rC) binding protein 3 | 0.0437679 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0432831 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0412323 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0408055 |
| KYNU | kynureninase | 0.0405356 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0404629 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0403402 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0403046 |
| INHBA | inhibin, beta A | 0.0402226 |
| RPS3 | ribosomal protein S3 | 0.0396699 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0394824 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0393232 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0376951 |
| FLNB | filamin B, beta | 0.037041 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0367419 |
| FMNL2 | formin-like 2 | 0.0365082 |
| CEP72 | centrosomal protein 72kDa | 0.0361481 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0354217 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0351521 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0349776 |
| TBXT | T-box transcription factor T | 0.0347291 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.032891 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0325786 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0323867 |
| EZR | ezrin | 0.0322551 |
| LAMA5 | laminin, alpha 5 | 0.0310837 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0309946 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0308164 |
| DUSP4 | dual specificity phosphatase 4 | 0.0299951 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0296581 |
| MSN | moesin | 0.0292623 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0289516 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0288993 |
| BMP6 | bone morphogenetic protein 6 | 0.0286513 |
| NRCAM | neuronal cell adhesion molecule | 0.0274432 |
| CD44 | CD44 molecule (Indian blood group) | 0.0268676 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0268578 |
| ATXN1 | ataxin 1 | 0.0267703 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0259261 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.025919 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0257065 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0256281 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0252214 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0249102 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.024701 |
| FAT1 | FAT atypical cadherin 1 | 0.0245401 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0243613 |
| FLNA | filamin A, alpha | 0.0243581 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0243479 |
| ALPK2 | alpha-kinase 2 | 0.023862 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0238022 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0235067 |
| SFTPA2 | surfactant protein A2 | 0.0234408 |
| NTN4 | netrin 4 | 0.0232342 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0231575 |
| VEGFA | vascular endothelial growth factor A | 0.0231532 |
| RPS18 | ribosomal protein S18 | 0.0228916 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.0227853 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0227561 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0226929 |
| SVIL | supervillin | 0.0221644 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0221251 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0219444 |
| PRELID2 | PRELI domain containing 2 | 0.0212638 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0211197 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0208444 |
| RGS2 | regulator of G-protein signaling 2 | 0.0206362 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0206186 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0205829 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0205414 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0202406 |
| CRLF2 | cytokine receptor-like factor 2 | 0.0198795 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0194709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.173321 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131144 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.122375 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.120209 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0812573 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0804675 |
| EFNA5 | ephrin-A5 | -0.0693344 |
| VIM | vimentin | -0.067925 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.066772 |
| CANX | calnexin | -0.0600541 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0572091 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0502804 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0426983 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0423113 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0420061 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0418094 |
| RPS24 | ribosomal protein S24 | -0.0409548 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0399179 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0384823 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0383361 |
| NCKAP5 | NCK-associated protein 5 | -0.0370678 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0365851 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0365482 |
| SMYD3 | SET and MYND domain containing 3 | -0.0361409 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0361069 |
| RPL35A | ribosomal protein L35a | -0.0323893 |
| PTMA | prothymosin, alpha | -0.0316292 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0315494 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0307961 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0306256 |
| NBEAL1 | neurobeachin-like 1 | -0.0298424 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0292269 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0270871 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0269293 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0256944 |
| MORF4L2 | mortality factor 4 like 2 | -0.025666 |
| RPLP1 | ribosomal protein, large, P1 | -0.0251305 |
| GNAS | GNAS complex locus | -0.0243687 |
| CADM2 | cell adhesion molecule 2 | -0.024342 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0238363 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0236091 |
| RAB1A | RAB1A, member RAS oncogene family | -0.022784 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0226483 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0225458 |
| RPS25 | ribosomal protein S25 | -0.0225428 |
| LSAMP | limbic system-associated membrane protein | -0.022436 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0221129 |
| DIAPH2 | diaphanous-related formin 2 | -0.0219122 |
| MAGT1 | magnesium transporter 1 | -0.0218775 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.021397 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0212218 |
| S100A6 | S100 calcium binding protein A6 | -0.0210079 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0208712 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0207948 |
| VCL | vinculin | -0.0207731 |
| RPL39 | ribosomal protein L39 | -0.0207068 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0197079 |
| TMSB10 | thymosin beta 10 | -0.0196589 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0194262 |
| RPS6 | ribosomal protein S6 | -0.0192539 |
| RPS23 | ribosomal protein S23 | -0.0189897 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0189064 |
| FBXO11 | F-box protein 11 | -0.0187215 |
| S100A10 | S100 calcium binding protein A10 | -0.0186218 |
| TKT | transketolase | -0.0185718 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0181285 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0180731 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0179387 |
| GOLGA4 | golgin A4 | -0.0176955 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | -0.01768 |
| CDK13 | cyclin-dependent kinase 13 | -0.0175443 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0173882 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | -0.0172193 |
| PCDH15 | protocadherin-related 15 | -0.0172132 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0171869 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0169895 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0169441 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0167741 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0167147 |
| ZNF804A | zinc finger protein 804A | -0.0164972 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0164841 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0164322 |
| GALNT15 | polypeptide N-acetylgalactosaminyltransferase 15 | -0.0163992 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0163667 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0163636 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.016262 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.0161615 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0161141 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0160358 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0159761 |
| USP34 | ubiquitin specific peptidase 34 | -0.0159219 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0159114 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0158852 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0158263 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0157893 |
| POTEF | POTE ankyrin domain family, member F | -0.0155224 |
| RPS8 | ribosomal protein S8 | -0.0154789 |
| AGR2 | anterior gradient 2 | -0.0154201 |
| RPS16 | ribosomal protein S16 | -0.0153984 |
| AHNAK | AHNAK nucleoprotein | -0.0153734 |