| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Adenosine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.195427 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.151327 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.120161 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.119699 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0889618 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0811688 |
| PEG10 | paternally expressed 10 | 0.0737362 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0651931 |
| CADM2 | cell adhesion molecule 2 | 0.0620694 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0606959 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0601703 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0581633 |
| MEIS2 | Meis homeobox 2 | 0.0564404 |
| NTM | neurotrimin | 0.0559974 |
| GSE1 | Gse1 coiled-coil protein | 0.0528697 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.05266 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0508119 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0506539 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0499461 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0492198 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0489473 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0434449 |
| PRELID2 | PRELI domain containing 2 | 0.0425326 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0424307 |
| VEGFA | vascular endothelial growth factor A | 0.0411255 |
| NFIA | nuclear factor I/A | 0.0387361 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0367522 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.036243 |
| PCDH7 | protocadherin 7 | 0.0361658 |
| METAP2 | methionyl aminopeptidase 2 | 0.0360111 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0356499 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0353602 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0349539 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0343482 |
| SMYD3 | SET and MYND domain containing 3 | 0.0332798 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0329902 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0329006 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0326763 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0323586 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0321843 |
| ANXA1 | annexin A1 | 0.0317133 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0316408 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0315831 |
| PRKD1 | protein kinase D1 | 0.0310933 |
| ENO1 | enolase 1, (alpha) | 0.0307134 |
| UTRN | utrophin | 0.0304578 |
| CALR | calreticulin | 0.0300662 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0290545 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.028896 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0288207 |
| WWOX | WW domain containing oxidoreductase | 0.0283153 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0283114 |
| SET | SET nuclear proto-oncogene | 0.0282123 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0280903 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0278033 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0276015 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0275346 |
| TENM2 | teneurin transmembrane protein 2 | 0.027333 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0272635 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0271447 |
| HMCN1 | hemicentin 1 | 0.0271134 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0270147 |
| LRRC4C | leucine rich repeat containing 4C | 0.0268037 |
| COL3A1 | collagen, type III, alpha 1 | 0.0266837 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0265788 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0264003 |
| PHIP | pleckstrin homology domain interacting protein | 0.0263302 |
| NONO | non-POU domain containing, octamer-binding | 0.0261865 |
| NGFR | nerve growth factor receptor | 0.0260479 |
| GPC3 | glypican 3 | 0.0259543 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0258337 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0255801 |
| RPL23 | ribosomal protein L23 | 0.0253314 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0252436 |
| NID1 | nidogen 1 | 0.0252339 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0250916 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0250346 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0249927 |
| METTL15 | methyltransferase like 15 | 0.0249639 |
| RPS4X | ribosomal protein S4, X-linked | 0.0245157 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0245003 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0240517 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0240205 |
| TOX | thymocyte selection-associated high mobility group box | 0.0239616 |
| NRDC | nardilysin convertase | 0.0239608 |
| SHROOM3 | shroom family member 3 | 0.0238001 |
| RPL3 | ribosomal protein L3 | 0.0237009 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0236552 |
| BRD2 | bromodomain containing 2 | 0.0234476 |
| TRIM2 | tripartite motif containing 2 | 0.0234374 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0233695 |
| LYST | lysosomal trafficking regulator | 0.0233034 |
| CEP290 | centrosomal protein 290kDa | 0.0232553 |
| PHF21A | PHD finger protein 21A | 0.023057 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0230068 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0229994 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0229852 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0229739 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0229505 |
| NFIB | nuclear factor I/B | 0.0229376 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.109084 |
| PTMA | prothymosin, alpha | -0.0951318 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0869523 |
| VIM | vimentin | -0.0790231 |
| SPAG9 | sperm associated antigen 9 | -0.0760541 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.073497 |
| RPS16 | ribosomal protein S16 | -0.0717392 |
| TMSB10 | thymosin beta 10 | -0.0688154 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0609815 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0581644 |
| AHNAK | AHNAK nucleoprotein | -0.0576643 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0557105 |
| USP3 | ubiquitin specific peptidase 3 | -0.0552458 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0549371 |
| RPL37 | ribosomal protein L37 | -0.0548041 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0524438 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0520646 |
| RPS27A | ribosomal protein S27a | -0.0505671 |
| RLF | rearranged L-myc fusion | -0.0503792 |
| RHEB | Ras homolog enriched in brain | -0.0502431 |
| RPLP1 | ribosomal protein, large, P1 | -0.0476628 |
| ANXA2 | annexin A2 | -0.0452723 |
| COL5A2 | collagen, type V, alpha 2 | -0.0448784 |
| ZNF292 | zinc finger protein 292 | -0.0448353 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0435991 |
| FBXO11 | F-box protein 11 | -0.0432932 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0432038 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0425978 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0419143 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.041455 |
| GNAS | GNAS complex locus | -0.0411658 |
| FOXP2 | forkhead box P2 | -0.0405314 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0401184 |
| RPL35A | ribosomal protein L35a | -0.0383748 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0379705 |
| RPS24 | ribosomal protein S24 | -0.0371101 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.036674 |
| RBM39 | RNA binding motif protein 39 | -0.0364415 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0362296 |
| ENAH | enabled homolog (Drosophila) | -0.0361436 |
| WDR43 | WD repeat domain 43 | -0.0360885 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0358513 |
| EMP1 | epithelial membrane protein 1 | -0.0358192 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0351963 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0351405 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0349629 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0349491 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0347375 |
| MTF2 | metal response element binding transcription factor 2 | -0.0347242 |
| S100A10 | S100 calcium binding protein A10 | -0.0346469 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.034184 |
| ZNF207 | zinc finger protein 207 | -0.0338806 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.033718 |
| RPS25 | ribosomal protein S25 | -0.0334904 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0332322 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0331396 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0330722 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0327665 |
| CAVIN1 | caveolae associated protein 1 | -0.0325375 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.032478 |
| DSTN | destrin (actin depolymerizing factor) | -0.0321504 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0320136 |
| FTL | ferritin, light polypeptide | -0.0317009 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0315542 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0314149 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0312986 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0312159 |
| RTN3 | reticulon 3 | -0.0310856 |
| NOP58 | NOP58 ribonucleoprotein | -0.0309487 |
| RBM25 | RNA binding motif protein 25 | -0.03074 |
| HMGB1 | high mobility group box 1 | -0.0304695 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0297874 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0295737 |
| HDAC2 | histone deacetylase 2 | -0.0294118 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0293976 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0292957 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0291799 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.029027 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0290179 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0289646 |
| PDGFC | platelet derived growth factor C | -0.028931 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0287169 |
| CENPE | centromere protein E, 312kDa | -0.0285141 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0284932 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0284742 |
| LYPLA1 | lysophospholipase I | -0.0282945 |
| PTK2 | protein tyrosine kinase 2 | -0.0281302 |
| CD2AP | CD2-associated protein | -0.0280474 |
| RPS8 | ribosomal protein S8 | -0.0279823 |
| RPL10A | ribosomal protein L10a | -0.0276005 |
| VMP1 | vacuole membrane protein 1 | -0.0275805 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0275102 |
| FOXC1 | forkhead box C1 | -0.0271717 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0271312 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0271134 |
| RPS13 | ribosomal protein S13 | -0.0270969 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0266569 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0266365 |
| YAP1 | Yes-associated protein 1 | -0.0264517 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0263976 |