Adenosine_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Adenosine perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Adenosine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.202073
EEF2 eukaryotic translation elongation factor 2 0.137105
HSPA8 heat shock 70kDa protein 8 0.0781825
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0649461
TMSB4X thymosin beta 4, X-linked 0.063715
ENO1 enolase 1, (alpha) 0.0635323
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0619983
RPL3 ribosomal protein L3 0.0608376
MKI67 marker of proliferation Ki-67 0.0563843
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0561191
EZR ezrin 0.0524359
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0514484
MATR3 matrin 3 0.0464281
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0457727
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0453329
LDHA lactate dehydrogenase A 0.0435574
SET SET nuclear proto-oncogene 0.0433988
EIF3A eukaryotic translation initiation factor 3, subunit A 0.0430113
PGK1 phosphoglycerate kinase 1 0.0421722
GLI2 GLI family zinc finger 2 0.0417584
RPS18 ribosomal protein S18 0.0412694
LOXL3 lysyl oxidase-like 3 0.0409818
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0404207
EIF4B eukaryotic translation initiation factor 4B 0.0402763
GSE1 Gse1 coiled-coil protein 0.0400291
APP amyloid beta (A4) precursor protein 0.0398716
AMOTL2 angiomotin like 2 0.0387689
PKM pyruvate kinase, muscle 0.0380469
GOLGA4 golgin A4 0.0380394
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0379261
TGFBR3 transforming growth factor, beta receptor III 0.0378632
ANXA1 annexin A1 0.0373925
FAT1 FAT atypical cadherin 1 0.0369222
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0367639
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.0365131
PLK2 polo-like kinase 2 0.0360139
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0353961
MYO5C myosin VC 0.0349924
TRERF1 transcriptional regulating factor 1 0.0339195
MACF1 microtubule-actin crosslinking factor 1 0.0332528
PNN pinin, desmosome associated protein 0.0332487
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0326627
CSF1 colony stimulating factor 1 (macrophage) 0.0324617
PYGB phosphorylase, glycogen; brain 0.0321806
CENPF centromere protein F, 350/400kDa 0.0316233
SPATS2L spermatogenesis associated, serine-rich 2-like 0.0312175
PHF3 PHD finger protein 3 0.0311142
VEGFA vascular endothelial growth factor A 0.0304383
ECT2 epithelial cell transforming 2 0.0299593
ZEB1 zinc finger E-box binding homeobox 1 0.0297927
HELZ helicase with zinc finger 0.0295194
CSNK1A1 casein kinase 1, alpha 1 0.0293937
RAD51B RAD51 paralog B 0.029066
IQGAP1 IQ motif containing GTPase activating protein 1 0.0288525
CKAP5 cytoskeleton associated protein 5 0.0285798
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0278793
KIF5B kinesin family member 5B 0.0277353
TJP1 tight junction protein 1 0.0275841
RPS2 ribosomal protein S2 0.027574
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.027408
EIF4H eukaryotic translation initiation factor 4H 0.0266511
CEP250 centrosomal protein 250kDa 0.0263617
NBAS neuroblastoma amplified sequence 0.0261719
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.025844
NAMPT nicotinamide phosphoribosyltransferase 0.025634
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.0256232
RAD21 RAD21 homolog (S. pombe) 0.0255898
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.0253835
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.024997
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.0247617
TAC4 tachykinin 4 (hemokinin) 0.0246904
MACROD2 MACRO domain containing 2 0.0243121
PLXNA1 plexin A1 0.0243094
DST dystonin 0.0239732
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.0239021
QKI QKI, KH domain containing, RNA binding 0.023812
SDK1 sidekick cell adhesion molecule 1 0.0238095
TPM4 tropomyosin 4 0.0236768
CSDE1 cold shock domain containing E1, RNA-binding 0.0236561
ZNF292 zinc finger protein 292 0.0236115
OGA O-GlcNAcase 0.0234241
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0234089
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0232031
MYH9 myosin, heavy chain 9, non-muscle 0.0231606
NCOR1 nuclear receptor corepressor 1 0.0231242
PRELID2 PRELI domain containing 2 0.0228261
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.0227798
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.0227568
RNF145 ring finger protein 145 0.0227108
TOP2B topoisomerase (DNA) II beta 180kDa 0.0226529
PRPF8 pre-mRNA processing factor 8 0.022274
SRRM2 serine/arginine repetitive matrix 2 0.0222305
KMT2C lysine (K)-specific methyltransferase 2C 0.0220091
MSI2 musashi RNA-binding protein 2 0.0216994
TUBB4B tubulin, beta 4B class IVb 0.0216052
ADAM10 ADAM metallopeptidase domain 10 0.021294
HDLBP high density lipoprotein binding protein 0.0211242
BRD4 bromodomain containing 4 0.0210767
ARID1A AT rich interactive domain 1A (SWI-like) 0.0208214
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0207424

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.30974
RPL35A ribosomal protein L35a -0.144061
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.121826
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.113973
CPED1 cadherin-like and PC-esterase domain containing 1 -0.108944
TPT1 tumor protein, translationally-controlled 1 -0.103436
PDE4B phosphodiesterase 4B, cAMP-specific -0.099041
S100A6 S100 calcium binding protein A6 -0.098613
PTMA prothymosin, alpha -0.0985279
ARL4C ADP-ribosylation factor-like 4C -0.087769
FOXP1 forkhead box P1 -0.0826177
PDE4D phosphodiesterase 4D, cAMP-specific -0.0801973
RPS23 ribosomal protein S23 -0.0784292
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.075361
RPS8 ribosomal protein S8 -0.0718468
RPS25 ribosomal protein S25 -0.0673333
RPLP1 ribosomal protein, large, P1 -0.0666783
CCND1 cyclin D1 -0.0658033
RPS19 ribosomal protein S19 -0.0636684
RPL19 ribosomal protein L19 -0.0631739
RPS6 ribosomal protein S6 -0.0586733
RPLP2 ribosomal protein, large, P2 -0.0578379
EIF1 eukaryotic translation initiation factor 1 -0.0560252
ACTG1 actin gamma 1 -0.055034
RPS16 ribosomal protein S16 -0.0548385
RPS24 ribosomal protein S24 -0.0527693
RPS13 ribosomal protein S13 -0.0463266
SSBP2 single-stranded DNA binding protein 2 -0.0462885
RPL9 ribosomal protein L9 -0.0460577
MYL12B myosin, light chain 12B, regulatory -0.043338
RPL27A ribosomal protein L27a -0.0427141
RPL34 ribosomal protein L34 -0.0426982
GARS1 glycyl-tRNA synthetase 1 -0.0421629
RPL36A ribosomal protein L36a -0.0419181
RPS15 ribosomal protein S15 -0.0418931
ZFAND3 zinc finger, AN1-type domain 3 -0.0418733
RPL12 ribosomal protein L12 -0.0412698
BMP10 bone morphogenetic protein 10 -0.0412458
RPL37 ribosomal protein L37 -0.0396135
GNAS GNAS complex locus -0.0395151
NBEA neurobeachin -0.0392915
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0392133
S100A9 S100 calcium binding protein A9 -0.0392072
RPL32 ribosomal protein L32 -0.0390331
RPL37A ribosomal protein L37a -0.0388093
VDAC1 voltage-dependent anion channel 1 -0.0385672
TMSB10 thymosin beta 10 -0.0385351
RPS29 ribosomal protein S29 -0.0373254
USP34 ubiquitin specific peptidase 34 -0.0369437
AHNAK AHNAK nucleoprotein -0.0367096
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0365911
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0363354
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) -0.0360194
DSCAM Down syndrome cell adhesion molecule -0.036004
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0355821
RPL10A ribosomal protein L10a -0.0353391
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0335074
DLG1 discs, large homolog 1 (Drosophila) -0.0331127
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0330721
RPL31 ribosomal protein L31 -0.0328446
SLC38A2 solute carrier family 38, member 2 -0.03271
RPL7A ribosomal protein L7a -0.0324294
RPL8 ribosomal protein L8 -0.0323048
RPS11 ribosomal protein S11 -0.0322034
JMJD1C jumonji domain containing 1C -0.0315648
S100A4 S100 calcium binding protein A4 -0.0310643
RPL28 ribosomal protein L28 -0.0310376
EML4 echinoderm microtubule associated protein like 4 -0.030721
RPL30 ribosomal protein L30 -0.0305737
RPL11 ribosomal protein L11 -0.0302735
EIF5B eukaryotic translation initiation factor 5B -0.0302421
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0300941
MLIP muscular LMNA-interacting protein -0.029851
RTN4 reticulon 4 -0.0292109
BIRC6 baculoviral IAP repeat containing 6 -0.0288926
IFI16 interferon, gamma-inducible protein 16 -0.0286169
EFNA5 ephrin-A5 -0.028613
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0281125
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0278707
RPS27A ribosomal protein S27a -0.0278531
IARS1 isoleucyl-tRNA synthetase 1 -0.0276913
RPL13A ribosomal protein L13a -0.0276458
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -0.0275364
PNISR PNN-interacting serine/arginine-rich protein -0.0265435
S100A10 S100 calcium binding protein A10 -0.0261424
TAS2R14 taste receptor, type 2, member 14 -0.0261226
UBE2K ubiquitin-conjugating enzyme E2K -0.0259564
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 -0.0252265
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0249629
DPYD dihydropyrimidine dehydrogenase -0.0248902
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0247893
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.0246313
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0244957
FNDC3B fibronectin type III domain containing 3B -0.0244409
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.0243935
ZMYND8 zinc finger, MYND-type containing 8 -0.0243114
INTS6 integrator complex subunit 6 -0.024311
EXT1 exostosin glycosyltransferase 1 -0.0242462
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0239469
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0237023