| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Adenosine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Adenosine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.268402 |
| MT2A | metallothionein 2A | 0.151405 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.1402 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0856904 |
| HLA-B | major histocompatibility complex, class I, B | 0.0844154 |
| COL6A3 | collagen, type VI, alpha 3 | 0.08292 |
| IL6 | interleukin 6 | 0.0750182 |
| B2M | beta-2-microglobulin | 0.0567808 |
| CALR | calreticulin | 0.0562769 |
| MAP1B | microtubule-associated protein 1B | 0.0554271 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0517189 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0515664 |
| CD44 | CD44 molecule (Indian blood group) | 0.0515659 |
| COL5A1 | collagen, type V, alpha 1 | 0.0509232 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0498903 |
| MSN | moesin | 0.0494287 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0487082 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0450155 |
| CST3 | cystatin C | 0.0441842 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0440248 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.043957 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0433616 |
| ENO1 | enolase 1, (alpha) | 0.0432657 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0425844 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0417388 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0413478 |
| HLA-A | major histocompatibility complex, class I, A | 0.041279 |
| GSE1 | Gse1 coiled-coil protein | 0.0411709 |
| EGFR | epidermal growth factor receptor | 0.0404562 |
| RAD51B | RAD51 paralog B | 0.0387444 |
| PLEC | plectin | 0.0386461 |
| NAV1 | neuron navigator 1 | 0.0374114 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0367415 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0351072 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0345301 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0344626 |
| MCL1 | myeloid cell leukemia 1 | 0.0339201 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0335509 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0332928 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.033236 |
| MYLK | myosin light chain kinase | 0.0328692 |
| STC2 | stanniocalcin 2 | 0.0326004 |
| RUNX1 | runt-related transcription factor 1 | 0.0323911 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0321334 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0319501 |
| LDHA | lactate dehydrogenase A | 0.0316871 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0315204 |
| MKI67 | marker of proliferation Ki-67 | 0.031436 |
| ECE1 | endothelin converting enzyme 1 | 0.0313145 |
| RPS12 | ribosomal protein S12 | 0.0311294 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0293866 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0284969 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0282538 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.02807 |
| NOTCH2 | notch 2 | 0.0280283 |
| EFNA5 | ephrin-A5 | 0.0278804 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0278672 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0277061 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0274523 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0274065 |
| SMTN | smoothelin | 0.0272278 |
| SYNJ2 | synaptojanin 2 | 0.0265626 |
| NEMF | nuclear export mediator factor | 0.0261046 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0256104 |
| SMYD3 | SET and MYND domain containing 3 | 0.0255083 |
| PRELID2 | PRELI domain containing 2 | 0.0253896 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0252837 |
| BRD2 | bromodomain containing 2 | 0.0252662 |
| FAM120A | family with sequence similarity 120A | 0.0251649 |
| RPL9 | ribosomal protein L9 | 0.0251389 |
| RO60 | Ro60, Y RNA binding protein | 0.0247445 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0247129 |
| TMEM51 | transmembrane protein 51 | 0.0240241 |
| RPL28 | ribosomal protein L28 | 0.0239366 |
| RIGI | RNA sensor RIG-I | 0.0237421 |
| SLK | STE20-like kinase | 0.0234907 |
| NRXN3 | neurexin 3 | 0.0234875 |
| OPTN | optineurin | 0.0234365 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0232229 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0230501 |
| BSG | basigin (Ok blood group) | 0.0226261 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0226195 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0225696 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0225609 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0224385 |
| EFHD2 | EF-hand domain family, member D2 | 0.0224244 |
| FN1 | fibronectin 1 | 0.0223549 |
| FAM193B | family with sequence similarity 193, member B | 0.0223247 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0219247 |
| BUB3 | BUB3 mitotic checkpoint protein | 0.0217554 |
| POTEF | POTE ankyrin domain family, member F | 0.0216836 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0216079 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0215094 |
| FLNA | filamin A, alpha | 0.0214587 |
| KIF5B | kinesin family member 5B | 0.0214265 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0214215 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0213229 |
| CDYL | chromodomain protein, Y-like | 0.0210224 |
| ATXN7 | ataxin 7 | 0.0209684 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.020899 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.18861 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115651 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0995584 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.073045 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0679714 |
| CALU | calumenin | -0.0655439 |
| AHNAK | AHNAK nucleoprotein | -0.0640891 |
| LOX | lysyl oxidase | -0.0619207 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0610993 |
| ANXA2 | annexin A2 | -0.0604371 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0533578 |
| VCL | vinculin | -0.0521201 |
| FNDC3A | fibronectin type III domain containing 3A | -0.048036 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0469238 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0454606 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0452129 |
| GLIS3 | GLIS family zinc finger 3 | -0.0445651 |
| CADM1 | cell adhesion molecule 1 | -0.0430778 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0427485 |
| NRP1 | neuropilin 1 | -0.0416888 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0415298 |
| WTAP | Wilms tumor 1 associated protein | -0.0413114 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0407574 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.040355 |
| TMSB10 | thymosin beta 10 | -0.0396877 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0392809 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0389539 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0388311 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0386373 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0385885 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0384488 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0379199 |
| COL1A2 | collagen, type I, alpha 2 | -0.037432 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0373672 |
| RPL35A | ribosomal protein L35a | -0.0359481 |
| PCM1 | pericentriolar material 1 | -0.0357526 |
| MORF4L2 | mortality factor 4 like 2 | -0.0349924 |
| CLTC | clathrin, heavy chain (Hc) | -0.0348118 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.034718 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0346623 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0342335 |
| NKTR | natural killer cell triggering receptor | -0.0341147 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.033844 |
| MAP4 | microtubule-associated protein 4 | -0.0335844 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.033413 |
| ASPH | aspartate beta-hydroxylase | -0.03274 |
| UBC | ubiquitin C | -0.0327004 |
| H3-3B | H3.3 histone B | -0.0323832 |
| ZNF292 | zinc finger protein 292 | -0.0322709 |
| PTMA | prothymosin, alpha | -0.0320653 |
| COL3A1 | collagen, type III, alpha 1 | -0.0320438 |
| CFDP1 | craniofacial development protein 1 | -0.0319487 |
| RAI14 | retinoic acid induced 14 | -0.0317499 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.031491 |
| RBM39 | RNA binding motif protein 39 | -0.0314728 |
| CLINT1 | clathrin interactor 1 | -0.0313533 |
| CALD1 | caldesmon 1 | -0.0309876 |
| MYOF | myoferlin | -0.0308202 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0305911 |
| VMP1 | vacuole membrane protein 1 | -0.0303182 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0298195 |
| AOPEP | aminopeptidase O (putative) | -0.0297873 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0296099 |
| MEF2A | myocyte enhancer factor 2A | -0.0295557 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.029409 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0294068 |
| SUCO | SUN domain containing ossification factor | -0.0292701 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0291133 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0290891 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0290199 |
| COG5 | component of oligomeric golgi complex 5 | -0.0289584 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0289264 |
| SDC4 | syndecan 4 | -0.0288836 |
| TMEM123 | transmembrane protein 123 | -0.0288414 |
| ZNF207 | zinc finger protein 207 | -0.0287361 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0287318 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0278015 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.027769 |
| STC1 | stanniocalcin 1 | -0.0276623 |
| HIP1 | huntingtin interacting protein 1 | -0.027591 |
| TAGLN2 | transgelin 2 | -0.0275884 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0275101 |
| CUL3 | cullin 3 | -0.0273364 |
| SRPK2 | SRSF protein kinase 2 | -0.0272845 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0271005 |
| AHR | aryl hydrocarbon receptor | -0.0270314 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0269331 |
| RAB31 | RAB31, member RAS oncogene family | -0.0267975 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0266655 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0265539 |
| ZNF133 | zinc finger protein 133 | -0.0263582 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0263408 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0261822 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0261522 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0257023 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0255021 |
| ZNF609 | zinc finger protein 609 | -0.0252798 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0252716 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0252668 |
| RLF | rearranged L-myc fusion | -0.0252237 |
