Adherens junction Gene Set

Dataset KEGG Pathways 2026
Category structural or functional annotations
Type pathway
Description A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments. (Gene Ontology, GO_0005912)
External Link https://www.kegg.jp/entry/hsa04520
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Genes

92 proteins participating in the Adherens junction pathway from the KEGG Pathways 2026 dataset.

Symbol Name
ACTG1 actin gamma 1
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
AFDN afadin, adherens junction formation factor
ARHGAP29 Rho GTPase activating protein 29
BAIAP2 BAI1-associated protein 2
CCM2 cerebral cavernous malformation 2
CDC42 cell division cycle 42
CDH5 cadherin 5, type 2 (vascular endothelium)
CREBBP CREB binding protein
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CSNK2B casein kinase 2, beta polypeptide
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
EGFR epidermal growth factor receptor
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FER fer (fps/fes related) tyrosine kinase
FGFR1 fibroblast growth factor receptor 1
FYN FYN proto-oncogene, Src family tyrosine kinase
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
HEG1 heart development protein with EGF-like domains 1
IGF1R insulin-like growth factor 1 receptor
INSR insulin receptor
IQGAP1 IQ motif containing GTPase activating protein 1
KRIT1 KRIT1, ankyrin repeat containing
LEF1 lymphoid enhancer-binding factor 1
LMO7 LIM domain 7
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MYL10 myosin, light chain 10, regulatory
MYL11 myosin light chain 11
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL12B myosin, light chain 12B, regulatory
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL5 myosin, light chain 5, regulatory
MYL7 myosin, light chain 7, regulatory
MYL9 myosin, light chain 9, regulatory
NCOA3 nuclear receptor coactivator 3
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
NECTIN1 nectin cell adhesion molecule 1
NECTIN2 nectin cell adhesion molecule 2
NECTIN3 nectin cell adhesion molecule 3
NECTIN4 nectin cell adhesion molecule 4
NLK nemo-like kinase
PARD3 par-3 family cell polarity regulator
PDCD10 programmed cell death 10
POTEF POTE ankyrin domain family, member F
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRM protein tyrosine phosphatase, receptor type, M
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RADIL Ras association and DIL domains
RAP1A RAP1A, member of RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RASIP1 Ras interacting protein 1
RHOA ras homolog family member A
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
SLTM SAFB-like, transcription modulator
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SORBS1 sorbin and SH3 domain containing 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TJP1 tight junction protein 1
VCL vinculin
WAS Wiskott-Aldrich syndrome
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WASF3 WAS protein family, member 3
WASL Wiskott-Aldrich syndrome-like
YES1 YES proto-oncogene 1, Src family tyrosine kinase