Adrenocortical Carcinoma Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An adrenal cortex cancer that forms in the outer layer of tissue of the adrenal gland and that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (Human Disease Ontology, DOID_3948)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D018268
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Genes

52 genes/proteins associated with the disease Adrenocortical Carcinoma from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
ZNRF3 zinc and ring finger 3 2.88009
TP53 tumor protein p53 2.88009
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 2.88009
BRAF B-Raf proto-oncogene, serine/threonine kinase 2.88009
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 2.88009
MED12 mediator complex subunit 12 2.88009
TERT telomerase reverse transcriptase 2.88009
EGFR epidermal growth factor receptor 2.88009
RB1 retinoblastoma 1 2.88009
MEN1 multiple endocrine neoplasia I 2.88009
TOP2A topoisomerase (DNA) II alpha 170kDa 2.88009
IGF2 insulin-like growth factor 2 2.88009
DAXX death-domain associated protein 2.88009
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.88009
RRM1 ribonucleotide reductase M1 2.88009
IGF1R insulin-like growth factor 1 receptor 2.88009
CDKN2A cyclin-dependent kinase inhibitor 2A 2.88009
MGMT O-6-methylguanine-DNA methyltransferase 1.32816
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.26298
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.25152
CFLAR CASP8 and FADD-like apoptosis regulator 1.20064
AXL AXL receptor tyrosine kinase 1.18751
SGK1 serum/glucocorticoid regulated kinase 1 1.18059
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.16137
PRKCD protein kinase C, delta 1.15022
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.1403
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.13313
PMP22 peripheral myelin protein 22 1.12048
WIF1 WNT inhibitory factor 1 1.10942
FASLG Fas ligand (TNF superfamily, member 6) 1.10033
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.0869
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.08372
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.06808
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.06734
RUNX3 runt-related transcription factor 3 1.052
CDC25C cell division cycle 25C 1.04721
EPO erythropoietin 1.04239
BCL2L1 BCL2-like 1 1.04239
THBS1 thrombospondin 1 1.04088
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.0353
RPS27L ribosomal protein S27-like 1.03493
SRGN serglycin 1.03493
KEAP1 kelch-like ECH-associated protein 1 1.03159
TP53I3 tumor protein p53 inducible protein 3 1.03159
BIRC2 baculoviral IAP repeat containing 2 1.03159
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.03046
TXNIP thioredoxin interacting protein 1.02596
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.02262
BRCA1 breast cancer 1, early onset 1.01739
BAK1 BCL2-antagonist/killer 1 1.01587
BTG3 BTG family, member 3 1.01361
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.01062