Advanced Breast Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C3495917
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Genes

138 genes associated with the disease Advanced Breast Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGAP24 Rho GTPase activating protein 24
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C1ORF234 chromosome 1 open reading frame 234
CCN1 cellular communication network factor 1
CD274 CD274 molecule
CD276 CD276 molecule
CD9 CD9 molecule
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL11A2 collagen, type XI, alpha 2
COMMD3-BMI1 COMMD3-BMI1 readthrough
CREBBP CREB binding protein
CSF3 colony stimulating factor 3 (granulocyte)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL8 chemokine (C-X-C motif) ligand 8
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DPYD dihydropyrimidine dehydrogenase
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FASN fatty acid synthase
FOXF2 forkhead box F2
GATA3 GATA binding protein 3
GLS glutaminase
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTP1 glutathione S-transferase pi 1
HDAC9 histone deacetylase 9
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB3 high mobility group box 3
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL2 interleukin 2
IL25 interleukin 25
IL6 interleukin 6
JAG1 jagged 1
KDM4A lysine (K)-specific demethylase 4A
KDR kinase insert domain receptor
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT7 keratin 7, type II
KSR1 kinase suppressor of ras 1
LIN28A lin-28 homolog A (C. elegans)
MAOA monoamine oxidase A
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPT microtubule-associated protein tau
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MED1 mediator complex subunit 1
MELK maternal embryonic leucine zipper kinase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKI67 marker of proliferation Ki-67
MPZL2 myelin protein zero-like 2
MSH3 mutS homolog 3
MTDH metadherin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYDGF myeloid-derived growth factor
NCOA1 nuclear receptor coactivator 1
NEU1 sialidase 1 (lysosomal sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF2 neurofibromin 2 (merlin)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOTCH3 notch 3
NQO1 NAD(P)H dehydrogenase, quinone 1
OCA2 oculocutaneous albinism II
PALB2 partner and localizer of BRCA2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIMREG PICALM interacting mitotic regulator
PLAT plasminogen activator, tissue
PRL prolactin
PSG2 pregnancy specific beta-1-glycoprotein 2
PTEN phosphatase and tensin homolog
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RHBDD2 rhomboid domain containing 2
RIPK2 receptor-interacting serine-threonine kinase 2
RRM1 ribonucleotide reductase M1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC2A4RG SLC2A4 regulator
SMAD3 SMAD family member 3
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SND1 staphylococcal nuclease and tudor domain containing 1
SOD2 superoxide dismutase 2, mitochondrial
SOX2 SRY (sex determining region Y)-box 2
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TGFB1 transforming growth factor, beta 1
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
TRAF2 TNF receptor-associated factor 2
TRIM28 tripartite motif containing 28
TWIST1 twist family bHLH transcription factor 1
TYMS thymidylate synthetase
UBL5 ubiquitin-like 5
USP8 ubiquitin specific peptidase 8
VEGFA vascular endothelial growth factor A
WIF1 WNT inhibitory factor 1
WNT1 wingless-type MMTV integration site family, member 1
WWOX WW domain containing oxidoreductase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPR1 xenotropic and polytropic retrovirus receptor 1