Afatinib Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A quinazoline compound having a 3-chloro-4-fluoroanilino group at the 4-position, a 4-dimethylamino-trans-but-2-enamido group at the 6-position, and an (S)-tetrahydrofuran-3-yloxy group at the 7-position. Used (as its dimaleate salt) for the first-line treatment of patients with metastatic non-small cell lung cancer. (Chemical Entities of Biological Interest Ontology, CHEBI_61390)
External Link http://www.drugbank.ca/drugs/DB08916
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Genes

4 interacting proteins for the Afatinib drug from the curated DrugBank Drug Targets dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4