Age Related Macular Degeneration Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision. (Human Disease Ontology, DOID_10871)
External Link https://www.disgenet.org/browser/0/1/0/C0242383
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Genes

633 genes associated with the disease Age Related Macular Degeneration in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD2 abhydrolase domain containing 2
ACAD10 acyl-CoA dehydrogenase family, member 10
ACAT1 acetyl-CoA acetyltransferase 1
ACAT2 acetyl-CoA acetyltransferase 2
ACE angiotensin I converting enzyme
ACO1 aconitase 1, soluble
ACTB actin, beta
ACVRL1 activin A receptor type II-like 1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
AGBL4 ATP/GTP binding protein-like 4
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIF1 allograft inflammatory factor 1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMD1 adenosylmethionine decarboxylase 1
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPTL2 angiopoietin-like 2
ANGPTL4 angiopoietin-like 4
ANO10 anoctamin 10
ANPEP alanyl (membrane) aminopeptidase
AOC3 amine oxidase, copper containing 3
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOE apolipoprotein E
APOM apolipoprotein M
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
ARHGAP21 Rho GTPase activating protein 21
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARMC9 armadillo repeat containing 9
ARMS2 age-related maculopathy susceptibility 2
ARNT aryl hydrocarbon receptor nuclear translocator
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATXN7 ataxin 7
B3GLCT beta 3-glucosyltransferase
BBS5 Bardet-Biedl syndrome 5
BBS9 Bardet-Biedl syndrome 9
BBX bobby sox homolog (Drosophila)
BCL2 B-cell CLL/lymphoma 2
BCO1 beta-carotene oxygenase 1
BDNF brain-derived neurotrophic factor
BEST1 bestrophin 1
BHLHE22 basic helix-loop-helix family, member e22
BMP4 bone morphogenetic protein 4
BMP6 bone morphogenetic protein 6
C1QTNF5 C1q and tumor necrosis factor related protein 5
C2 complement component 2
C2ORF44 chromosome 2 open reading frame 44
C3 complement component 3
C3AR1 complement component 3a receptor 1
C4A complement component 4A (Rodgers blood group)
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C5 complement component 5
C9 complement component 9
CA13 carbonic anhydrase XIII
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNG3 calcium channel, voltage-dependent, gamma subunit 3
CALCR calcitonin receptor
CALR calreticulin
CAPG capping protein (actin filament), gelsolin-like
CAPN5 calpain 5
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL2 chemokine (C-C motif) ligand 2
CCL22 chemokine (C-C motif) ligand 22
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CD200 CD200 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CD5L CD5 molecule-like
CD93 CD93 molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH7 cadherin 7, type 2
CDHR1 cadherin-related family member 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEP78 centrosomal protein 78kDa
CETP cholesteryl ester transfer protein, plasma
CFB complement factor B
CFD complement factor D (adipsin)
CFH complement factor H
CFHR1 complement factor H-related 1
CFHR2 complement factor H-related 2
CFHR3 complement factor H-related 3
CFHR4 complement factor H-related 4
CFHR5 complement factor H-related 5
CFI complement factor I
CFP complement factor properdin
CGRRF1 cell growth regulator with ring finger domain 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHMP2B charged multivesicular body protein 2B
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CIAO3 cytosolic iron-sulfur assembly component 3
CLN3 ceroid-lipofuscinosis, neuronal 3
CLU clusterin
CLUL1 clusterin-like 1 (retinal)
CNGB3 cyclic nucleotide gated channel beta 3
CNN2 calponin 2
CNR1 cannabinoid receptor 1 (brain)
CNTF ciliary neurotrophic factor
COL10A1 collagen, type X, alpha 1
COL18A1 collagen, type XVIII, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL8A1 collagen, type VIII, alpha 1
CP ceruloplasmin (ferroxidase)
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRX cone-rod homeobox
CRYAB crystallin, alpha B
CRYBB1 crystallin, beta B1
CRYBB2 crystallin, beta B2
CST3 cystatin C
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTRB1 chymotrypsinogen B1
CTRB2 chymotrypsinogen B2
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DAPL1 death associated protein-like 1
DCP1B decapping mRNA 1B
DCTN4 dynactin 4 (p62)
DDIT4 DNA-damage-inducible transcript 4
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DIAPH2 diaphanous-related formin 2
DICER1 dicer 1, ribonuclease type III
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DMBT1 deleted in malignant brain tumors 1
DMD dystrophin
DMRT1 doublesex and mab-3 related transcription factor 1
DNASE1 deoxyribonuclease I
DPF3 D4, zinc and double PHD fingers, family 3
E2F2 E2F transcription factor 2
ECM1 extracellular matrix protein 1
EDF1 endothelial differentiation-related factor 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGF epidermal growth factor
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELN elastin
ELOVL4 ELOVL fatty acid elongase 4
EPAS1 endothelial PAS domain protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPO erythropoietin
ERCC2 excision repair cross-complementation group 2
ERCC3 excision repair cross-complementation group 3
ERCC6 excision repair cross-complementation group 6
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EXOC3L2 exocyst complex component 3-like 2
EYS eyes shut homolog (Drosophila)
EZR ezrin
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F9 coagulation factor IX
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FAM155B family with sequence similarity 155, member B
FAM58A family with sequence similarity 58, member A
FBLN5 fibulin 5
FBN2 fibrillin 2
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FECH ferrochelatase
FGD6 FYVE, RhoGEF and PH domain containing 6
FGF2 fibroblast growth factor 2 (basic)
FGF21 fibroblast growth factor 21
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FILIP1L filamin A interacting protein 1-like
FKBPL FK506 binding protein like
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FMOD fibromodulin
FN1 fibronectin 1
FNDC1 fibronectin type III domain containing 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FPR1 formyl peptide receptor 1
FRK fyn-related Src family tyrosine kinase
FSCN2 fascin actin-bundling protein 2, retinal
FTCD formimidoyltransferase cyclodeaminase
FTMT ferritin mitochondrial
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZD4 frizzled class receptor 4
G6PD glucose-6-phosphate dehydrogenase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALNS galactosamine (N-acetyl)-6-sulfatase
GAS6 growth arrest-specific 6
GAST gastrin
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GDF2 growth differentiation factor 2
GDF6 growth differentiation factor 6
GEM GTP binding protein overexpressed in skeletal muscle
GEMIN2 gem (nuclear organelle) associated protein 2
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GPR75 G protein-coupled receptor 75
GPX3 glutathione peroxidase 3
GRAP2 GRB2-related adaptor protein 2
GRK5 G protein-coupled receptor kinase 5
GSR glutathione reductase
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM5 glutathione S-transferase mu 5
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GSTZ1 glutathione S-transferase zeta 1
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF2H5 general transcription factor IIH, polypeptide 5
GUCA1A guanylate cyclase activator 1A (retina)
HAMP hepcidin antimicrobial peptide
HDAC11 histone deacetylase 11
HDAC9 histone deacetylase 9
HEPH hephaestin
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIC1 hypermethylated in cancer 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMCN1 hemicentin 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HP haptoglobin
HPGDS hematopoietic prostaglandin D synthase
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPA4 heat shock 70kDa protein 4
HSPG2 heparan sulfate proteoglycan 2
HSPH1 heat shock 105kDa/110kDa protein 1
HTRA1 HtrA serine peptidase 1
HYLS1 hydrolethalus syndrome 1
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
IFT54 intraflagellar transport 54
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17D interleukin 17D
IL17RA interleukin 17 receptor A
IL17RC interleukin 17 receptor C
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL27 interleukin 27
IL27RA interleukin 27 receptor, alpha
IL2RA interleukin 2 receptor, alpha
IL2RG interleukin 2 receptor, gamma
IL33 interleukin 33
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IMPG1 interphotoreceptor matrix proteoglycan 1
IMPG2 interphotoreceptor matrix proteoglycan 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITM2B integral membrane protein 2B
KCNT2 potassium channel, sodium activated subfamily T, member 2
KDR kinase insert domain receptor
KEAP1 kelch-like ECH-associated protein 1
KERA keratocan
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIDINS220 kinase D-interacting substrate, 220kDa
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KLF5 Kruppel-like factor 5 (intestinal)
KRT8 keratin 8, type II
LAMA3 laminin, alpha 3
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LCN2 lipocalin 2
LCN9 lipocalin 9
LGALS1 lectin, galactoside-binding, soluble, 1
LIPC lipase, hepatic
LOXL1 lysyl oxidase-like 1
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRTM4 leucine rich repeat transmembrane neuronal 4
LTB4R leukotriene B4 receptor
MAN2B1 mannosidase, alpha, class 2B, member 1
MAP2 microtubule-associated protein 2
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MBL2 mannose-binding lectin (protein C) 2, soluble
MCUB mitochondrial calcium uniporter dominant negative subunit beta
MDM1 Mdm1 nuclear protein homolog (mouse)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
METAP2 methionyl aminopeptidase 2
MFGE8 milk fat globule-EGF factor 8 protein
MFRP membrane frizzled-related protein
MFSD8 major facilitator superfamily domain containing 8
MGST1 microsomal glutathione S-transferase 1
MIA3 melanoma inhibitory activity family, member 3
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP20 matrix metallopeptidase 20
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MNAT1 MNAT CDK-activating kinase assembly factor 1
MPLKIP M-phase specific PLK1 interacting protein
MT-ND2 MTND2
MT2A metallothionein 2A
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTTP microsomal triglyceride transfer protein
MUTYH mutY homolog
MYDGF myeloid-derived growth factor
MYO5A myosin VA (heavy chain 12, myoxin)
MYO7A myosin VIIA
MYOG myogenin (myogenic factor 4)
MYOM2 myomesin 2
MYRIP myosin VIIA and Rab interacting protein
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCAM1 neural cell adhesion molecule 1
NECTIN2 nectin cell adhesion molecule 2
NELFE negative elongation factor complex member E
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NOA1 nitric oxide associated 1
NOP56 NOP56 ribonucleoprotein
NOS2 nitric oxide synthase 2, inducible
NOTCH4 notch 4
NPHP1 nephronophthisis 1 (juvenile)
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR2E3 nuclear receptor subfamily 2, group E, member 3
NT5DC1 5'-nucleotidase domain containing 1
NUP62 nucleoporin 62kDa
OCA2 oculocutaneous albinism II
OGG1 8-oxoguanine DNA glycosylase
OPTC opticin
OSBP2 oxysterol binding protein 2
OTX2 orthodenticle homeobox 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAGR1 PAXIP1 associated glutamate-rich protein 1
PARP1 poly (ADP-ribose) polymerase 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PBX2 pre-B-cell leukemia homeobox 2
PCDHGA12 protocadherin gamma subfamily A, 12
PDE5A phosphodiesterase 5A, cGMP-specific
PEA15 phosphoprotein enriched in astrocytes 15
PELI3 pellino E3 ubiquitin protein ligase family member 3
PEX1 peroxisomal biogenesis factor 1
PGF placental growth factor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PILRA paired immunoglobin-like type 2 receptor alpha
PITPNM3 PITPNM family member 3
PLA2G12A phospholipase A2, group XIIA
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEK pleckstrin
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLG plasminogen
PLTP phospholipid transfer protein
PLXNA2 plexin A2
PNPLA2 patatin-like phospholipase domain containing 2
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PON1 paraoxonase 1
PON2 paraoxonase 2
POSTN periostin, osteoblast specific factor
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPT1 palmitoyl-protein thioesterase 1
PRCD progressive rod-cone degeneration
PROK1 prokineticin 1
PROM1 prominin 1
PRPF31 pre-mRNA processing factor 31
PRPH peripherin
PRPH2 peripherin 2 (retinal degeneration, slow)
PRSS50 protease, serine, 50
PTEN phosphatase and tensin homolog
PTX3 pentraxin 3, long
RAD51 RAD51 recombinase
RAD51B RAD51 paralog B
RAP1A RAP1A, member of RAS oncogene family
RAX2 retina and anterior neural fold homeobox 2
RBM45 RNA binding motif protein 45
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RDH8 retinol dehydrogenase 8 (all-trans)
REG1A regenerating islet-derived 1 alpha
RENBP renin binding protein
REST RE1-silencing transcription factor
RFC2 replication factor C (activator 1) 2, 40kDa
RGR retinal G protein coupled receptor
RGS10 regulator of G-protein signaling 10
RHO rhodopsin
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RLBP1 retinaldehyde binding protein 1
RNF113A ring finger protein 113A
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROM1 retinal outer segment membrane protein 1
RORA RAR-related orphan receptor A
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RP1L1 retinitis pigmentosa 1-like 1
RPE ribulose-5-phosphate-3-epimerase
RPE65 retinal pigment epithelium-specific protein 65kDa
RPGR retinitis pigmentosa GTPase regulator
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RREB1 ras responsive element binding protein 1
RS1 retinoschisin 1
RTEL1 regulator of telomere elongation helicase 1
SCAF11 SR-related CTD-associated factor 11
SCAPER S-phase cyclin A-associated protein in the ER
SCARB1 scavenger receptor class B, member 1
SCD5 stearoyl-CoA desaturase 5
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SESN2 sestrin 2
SET SET nuclear proto-oncogene
SETD2 SET domain containing 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGSM3 small G protein signaling modulator 3
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SLPI secretory leukocyte peptidase inhibitor
SLURP1 secreted LY6/PLAUR domain containing 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SPG11 spastic paraplegia 11 (autosomal recessive)
SPHK1 sphingosine kinase 1
SQSTM1 sequestosome 1
SRL sarcalumenin
SRM spermidine synthase
SRPK2 SRSF protein kinase 2
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STC1 stanniocalcin 1
STING1 stimulator of interferon response cGAMP interactor 1
STK19 serine/threonine kinase 19
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
SUCNR1 succinate receptor 1
SYCE1 synaptonemal complex central element protein 1
SYN3 synapsin III
TBK1 TANK-binding kinase 1
TBPL1 TBP-like 1
TDRD9 tudor domain containing 9
TEP1 telomerase-associated protein 1
TERF2 telomeric repeat binding factor 2
TF transferrin
TFR2 transferrin receptor 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TMEM97 transmembrane protein 97
TNC tenascin C
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNMD tenomodulin
TNXB tenascin XB
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TRA2B transformer 2 beta homolog (Drosophila)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TREM2 triggering receptor expressed on myeloid cells 2
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSHZ1 teashirt zinc finger homeobox 1
TSPAN7 tetraspanin 7
TSPO translocator protein (18kDa)
TST thiosulfate sulfurtransferase (rhodanese)
TTC8 tetratricopeptide repeat domain 8
TTN titin
TTPA tocopherol (alpha) transfer protein
TXN thioredoxin
TXNIP thioredoxin interacting protein
UBE3D ubiquitin protein ligase E3D
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UNG uracil-DNA glycosylase
USP6 ubiquitin specific peptidase 6
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIM vimentin
VLDLR very low density lipoprotein receptor
VSX1 visual system homeobox 1
VTN vitronectin
VWF von Willebrand factor
WNT7A wingless-type MMTV integration site family, member 7A
WNT7B wingless-type MMTV integration site family, member 7B
XCL1 chemokine (C motif) ligand 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPR1 xenotropic and polytropic retrovirus receptor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XYLT1 xylosyltransferase I
XYLT2 xylosyltransferase II
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP36 ZFP36 ring finger protein
ZFYVE26 zinc finger, FYVE domain containing 26