Age-Related Cataract Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0036646
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Genes

85 genes associated with the disease Age-Related Cataract in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOE apolipoprotein E
AQP1 aquaporin 1 (Colton blood group)
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
BCL2L2 BCL2-like 2
BDNF brain-derived neurotrophic factor
BFSP1 beaded filament structural protein 1, filensin
C3 complement component 3
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CD14 CD14 molecule
CD19 CD19 molecule
CNTF ciliary neurotrophic factor
COL11A2 collagen, type XI, alpha 2
CRYAA crystallin, alpha A
CRYAB crystallin, alpha B
CRYBB2 crystallin, beta B2
CRYGD crystallin, gamma D
EFNA5 ephrin-A5
EPHA1 EPH receptor A1
EPHA2 EPH receptor A2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERN1 endoplasmic reticulum to nucleus signaling 1
EZR ezrin
FAM188B family with sequence similarity 188, member B
FTL ferritin, light polypeptide
G6PD glucose-6-phosphate dehydrogenase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALK1 galactokinase 1
GJA3 gap junction protein, alpha 3, 46kDa
GJA8 gap junction protein, alpha 8, 50kDa
GPX1 glutathione peroxidase 1
GPX4 glutathione peroxidase 4
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTM3 glutathione S-transferase mu 3 (brain)
GSTO1 glutathione S-transferase omega 1
GSTO2 glutathione S-transferase omega 2
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HPGDS hematopoietic prostaglandin D synthase
HSF4 heat shock transcription factor 4
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
IDO1 indoleamine 2,3-dioxygenase 1
IL1F10 interleukin 1 family, member 10 (theta)
IL2 interleukin 2
IL37 interleukin 37
KEAP1 kelch-like ECH-associated protein 1
KL klotho
KLC1 kinesin light chain 1
LIM2 lens intrinsic membrane protein 2, 19kDa
LMNA lamin A/C
LOC102724652 alpha-crystallin A chain
LOXL1 lysyl oxidase-like 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NFE2L2 nuclear factor, erythroid 2-like 2
OGG1 8-oxoguanine DNA glycosylase
PARP1 poly (ADP-ribose) polymerase 1
PLCD3 phospholipase C, delta 3
PRDX6 peroxiredoxin 6
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIRT1 sirtuin 1
SLC16A12 solute carrier family 16, member 12
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SOD1 superoxide dismutase 1, soluble
SOD3 superoxide dismutase 3, extracellular
TDRD7 tudor domain containing 7
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TUG1 taurine up-regulated 1 (non-protein coding)
TXNRD1 thioredoxin reductase 1
TXNRD2 thioredoxin reductase 2
WRN Werner syndrome, RecQ helicase-like
XPC xeroderma pigmentosum, complementation group C
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF350 zinc finger protein 350