Age-Related Cognitive Decline Gene Set
Genes
23 genes associated with the disease Age-Related Cognitive Decline in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
| Symbol |
Name |
|
APOE
|
apolipoprotein E
|
|
APP
|
amyloid beta (A4) precursor protein
|
|
ARNTL
|
aryl hydrocarbon receptor nuclear translocator-like
|
|
BDNF
|
brain-derived neurotrophic factor
|
|
BGLAP
|
bone gamma-carboxyglutamate (gla) protein
|
|
CCL11
|
chemokine (C-C motif) ligand 11
|
|
CLOCK
|
clock circadian regulator
|
|
DAO
|
D-amino-acid oxidase
|
|
DEK
|
DEK proto-oncogene
|
|
ESR1
|
estrogen receptor 1
|
|
ESR2
|
estrogen receptor 2 (ER beta)
|
|
HDAC3
|
histone deacetylase 3
|
|
IGF1
|
insulin-like growth factor 1 (somatomedin C)
|
|
IL1B
|
interleukin 1, beta
|
|
LRP2
|
low density lipoprotein receptor-related protein 2
|
|
MAOB
|
monoamine oxidase B
|
|
PDE2A
|
phosphodiesterase 2A, cGMP-stimulated
|
|
PER2
|
period circadian clock 2
|
|
PROS1
|
protein S (alpha)
|
|
SIRT1
|
sirtuin 1
|
|
SIRT2
|
sirtuin 2
|
|
SOD2
|
superoxide dismutase 2, mitochondrial
|
|
SORL1
|
sortilin-related receptor, L(DLR class) A repeats containing
|