Aggresome Gene Set

Dataset COMPARTMENTS Experimental Protein Localization Evidence Scores 2025
Category proteomics
Type cellular component
Description An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules. (Gene Ontology, GO_0016235)
External Link http://purl.obolibrary.org/obo/GO_0016235
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Genes

56 proteins localized to the Aggresome cellular component in low- or high-throughput protein localization assays from the COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
TSPOAP1 TSPO associated protein 1 2.08
ITFG1 integrin alpha FG-GAP repeat containing 1 1.869
RSBN1L round spermatid basic protein 1-like 1.844
TMEM131 transmembrane protein 131 1.814
ADCY8 adenylate cyclase 8 (brain) 1.751
GPR180 G protein-coupled receptor 180 1.714
ZNF189 zinc finger protein 189 1.714
CCT8 chaperonin containing TCP1, subunit 8 (theta) 1.684
DOK6 docking protein 6 1.677
ARHGAP35 Rho GTPase activating protein 35 1.623
TRIM66 tripartite motif containing 66 1.623
FAIM2 Fas apoptotic inhibitory molecule 2 1.623
ABI1 abl-interactor 1 1.623
ERMARD ER membrane-associated RNA degradation 1.623
XRN2 5'-3' exoribonuclease 2 1.614
KIRREL1 kirre like nephrin family adhesion molecule 1 1.613
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 1.607
ZFP69 ZFP69 zinc finger protein 1.58
IRF2BP1 interferon regulatory factor 2 binding protein 1 1.571
NR2C1 nuclear receptor subfamily 2, group C, member 1 1.569
UNC13B unc-13 homolog B (C. elegans) 1.568
ZNF449 zinc finger protein 449 1.568
VIL1 villin 1 1.549
MTMR3 myotubularin related protein 3 1.536
JAZF1 JAZF zinc finger 1 1.532
IRS2 insulin receptor substrate 2 1.532
TPGS1 tubulin polyglutamylase complex subunit 1 1.532
SIPA1L2 signal-induced proliferation-associated 1 like 2 1.532
SFMBT2 Scm-like with four mbt domains 2 1.486
CALN1 calneuron 1 1.486
WDR37 WD repeat domain 37 1.472
EEF2 eukaryotic translation elongation factor 2 1.465
ZNHIT6 zinc finger, HIT-type containing 6 1.463
LIN28B lin-28 homolog B (C. elegans) 1.459
RTL5 retrotransposon Gag like 5 1.459
PGM3 phosphoglucomutase 3 1.451
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 1.441
SEC62 SEC62 homolog (S. cerevisiae) 1.441
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 1.441
MVB12A multivesicular body subunit 12A 1.44
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.439
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 1.439
ACVR1C activin A receptor, type IC 1.439
SLFN11 schlafen family member 11 1.438
ENTREP2 endosomal transmembrane epsin interactor 2 1.418
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 1.417
BTN3A1 butyrophilin, subfamily 3, member A1 1.411
UXT ubiquitously-expressed, prefoldin-like chaperone 1.395
PFDN5 prefoldin subunit 5 1.395
SYNE2 spectrin repeat containing, nuclear envelope 2 1.393
FGF5 fibroblast growth factor 5 1.388
DBF4B DBF4 zinc finger B 1.386
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 1.38
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) 1.376
CABIN1 calcineurin binding protein 1 1.376
ANOS1 anosmin 1 1.373