Aggresome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules. (Gene Ontology, GO_0016235)
External Link http://amigo.geneontology.org/amigo/term/GO:0016235
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Genes

1000 proteins co-occuring with the Aggresome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
HDAC6 histone deacetylase 6 3.407
SQSTM1 sequestosome 1 2.845
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 2.753
BAG3 BCL2-associated athanogene 3 2.708
HSPA4 heat shock 70kDa protein 4 2.699
ATXN3 ataxin 3 2.632
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 2.63
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 2.627
ATXN3L ataxin 3-like 2.595
SNCAIP synuclein, alpha interacting protein 2.589
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.53
HDAC9 histone deacetylase 9 2.527
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.465
VCP valosin containing protein 2.459
HSPB8 heat shock 22kDa protein 8 2.455
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.401
PRKN parkin RBR E3 ubiquitin protein ligase 2.397
BECN1 beclin 1, autophagy related 2.378
NBR1 neighbor of BRCA1 gene 1 2.374
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.353
UBQLN1 ubiquilin 1 2.327
HSPA8 heat shock 70kDa protein 8 2.313
TARDBP TAR DNA binding protein 2.273
ATG5 autophagy related 5 2.263
HCLS1 hematopoietic cell-specific Lyn substrate 1 2.26
ATG7 autophagy related 7 2.257
CTTN cortactin 2.251
ZUP1 zinc finger containing ubiquitin peptidase 1 2.239
SOD1 superoxide dismutase 1, soluble 2.227
UBD ubiquitin D 2.214
WDFY3 WD repeat and FYVE domain containing 3 2.213
TRIM50 tripartite motif containing 50 2.208
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.202
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 2.192
BAG1 BCL2-associated athanogene 2.179
TP53 tumor protein p53 2.178
UBQLN2 ubiquilin 2 2.175
CD300C CD300c molecule 2.171
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.168
HDAC10 histone deacetylase 10 2.149
CTRL chymotrypsin-like 2.13
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.128
GABARAPL1 GABA(A) receptor-associated protein like 1 2.121
PINK1 PTEN induced putative kinase 1 2.118
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 2.116
HSPB1 heat shock 27kDa protein 1 2.114
HDAC11 histone deacetylase 11 2.113
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.106
HDAC1 histone deacetylase 1 2.083
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 2.078
ULK1 unc-51 like autophagy activating kinase 1 2.062
OPTN optineurin 2.061
PRNP prion protein 2.057
ATG12 autophagy related 12 2.05
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 2.039
ZNF629 zinc finger protein 629 2.023
HSPB2 heat shock 27kDa protein 2 2.023
ZNF763 zinc finger protein 763 2.023
ZNF44 zinc finger protein 44 2.023
ZNF501 zinc finger protein 501 2.023
ZNF436 zinc finger protein 436 2.021
BCL2 B-cell CLL/lymphoma 2 2.01
ZNF569 zinc finger protein 569 1.998
CALCOCO2 calcium binding and coiled-coil domain 2 1.991
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.985
XBP1 X-box binding protein 1 1.983
UBQLN4 ubiquilin 4 1.983
HSPB3 heat shock 27kDa protein 3 1.978
FUS FUS RNA binding protein 1.973
PARK7 parkinson protein 7 1.969
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 1.958
METAP1 methionyl aminopeptidase 1 1.958
CTIF CBP80/20-dependent translation initiation factor 1.952
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.95
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.948
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 1.947
USP9X ubiquitin specific peptidase 9, X-linked 1.941
CANX calnexin 1.936
HDAC3 histone deacetylase 3 1.932
DES desmin 1.932
DNAH8 dynein, axonemal, heavy chain 8 1.931
MAP1S microtubule-associated protein 1S 1.925
SIRT2 sirtuin 2 1.924
LAMP1 lysosomal-associated membrane protein 1 1.922
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.919
MAPT microtubule-associated protein tau 1.916
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.914
TFEB transcription factor EB 1.91
APP amyloid beta (A4) precursor protein 1.9
AMBRA1 autophagy/beclin-1 regulator 1 1.899
GABARAP GABA(A) receptor-associated protein 1.886
ATXN1 ataxin 1 1.886
ADRM1 adhesion regulating molecule 1 1.881
HDAC4 histone deacetylase 4 1.878
ATG14 autophagy related 14 1.872
HDAC2 histone deacetylase 2 1.857
HDAC8 histone deacetylase 8 1.855
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.855
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.853
DCTN2 dynactin 2 (p50) 1.846
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.831
ERN1 endoplasmic reticulum to nucleus signaling 1 1.831
MAP1B microtubule-associated protein 1B 1.829
PXMP2 peroxisomal membrane protein 2, 22kDa 1.824
UBE3A ubiquitin protein ligase E3A 1.819
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase 1.816
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.815
ATF6 activating transcription factor 6 1.814
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 1.813
UBQLN3 ubiquilin 3 1.809
LAMP2 lysosomal-associated membrane protein 2 1.799
SIRT1 sirtuin 1 1.795
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 1.792
STIP1 stress-induced phosphoprotein 1 1.786
DCTN1 dynactin 1 1.786
CRBN cereblon 1.785
RB1CC1 RB1-inducible coiled-coil 1 1.782
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.78
ATG3 autophagy related 3 1.78
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 1.78
UBA1 ubiquitin-like modifier activating enzyme 1 1.775
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 1.772
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.771
ATG13 autophagy related 13 1.762
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.757
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.755
TPPP tubulin polymerization promoting protein 1.755
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.754
CLSTN1 calsyntenin 1 1.753
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha 1.743
MCL1 myeloid cell leukemia 1 1.741
GFAP glial fibrillary acidic protein 1.74
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.726
BCL2L1 BCL2-like 1 1.725
TP53INP1 tumor protein p53 inducible nuclear protein 1 1.718
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 1.716
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.715
KEAP1 kelch-like ECH-associated protein 1 1.714
UBE2N ubiquitin-conjugating enzyme E2N 1.704
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.7
LRRK2 leucine-rich repeat kinase 2 1.693
TRAT1 T cell receptor associated transmembrane adaptor 1 1.692
PARP1 poly (ADP-ribose) polymerase 1 1.684
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 1.678
SUMO1 small ubiquitin-like modifier 1 1.673
HSPA1B heat shock 70kDa protein 1B 1.672
TNF tumor necrosis factor 1.667
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.664
UFD1 ubiquitin recognition factor in ER associated degradation 1 1.664
DCP1A decapping mRNA 1A 1.663
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.662
UBE2S ubiquitin-conjugating enzyme E2S 1.66
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.657
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.656
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 1.653
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 1.647
UBA6 ubiquitin-like modifier activating enzyme 6 1.645
DISC1 disrupted in schizophrenia 1 1.644
DDIT3 DNA-damage-inducible transcript 3 1.643
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.64
NFE2L2 nuclear factor, erythroid 2-like 2 1.637
CYCS cytochrome c, somatic 1.623
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 1.621
PXDNL peroxidasin-like 1.621
PXDN peroxidasin 1.62
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.618
FBF1 Fas (TNFRSF6) binding factor 1 1.61
NUB1 negative regulator of ubiquitin-like proteins 1 1.61
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.609
ANXA5 annexin A5 1.607
UBB ubiquitin B 1.606
TBK1 TANK-binding kinase 1 1.605
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.603
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.603
FAM120B family with sequence similarity 120B 1.595
UVRAG UV radiation resistance associated 1.594
ATM ATM serine/threonine kinase 1.594
ATG10 autophagy related 10 1.59
CALR calreticulin 1.585
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.582
BAX BCL2-associated X protein 1.577
ATG101 autophagy related 101 1.576
IFNG interferon, gamma 1.575
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.575
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 1.573
JUN jun proto-oncogene 1.571
XPO1 exportin 1 1.564
AREG amphiregulin 1.563
CTSD cathepsin D 1.56
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.56
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 1.556
IL6 interleukin 6 1.555
ATXN2 ataxin 2 1.554
CUL5 cullin 5 1.552
SP100 SP100 nuclear antigen 1.545
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.536
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 1.535
PSEN1 presenilin 1 1.532
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.532
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.531
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.528
PTEN phosphatase and tensin homolog 1.527
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.524
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 1.524
IL1B interleukin 1, beta 1.521
IKZF3 IKAROS family zinc finger 3 (Aiolos) 1.521
PCNT pericentrin 1.52
UBE2K ubiquitin-conjugating enzyme E2K 1.517
ATP13A2 ATPase type 13A2 1.515
HOOK1 hook microtubule-tethering protein 1 1.513
TRIM5 tripartite motif containing 5 1.51
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.51
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.509
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 1.508
UBR1 ubiquitin protein ligase E3 component n-recognin 1 1.508
EGFR epidermal growth factor receptor 1.5
ISG15 ISG15 ubiquitin-like modifier 1.498
NFE2L1 nuclear factor, erythroid 2-like 1 1.497
RAD23B RAD23 homolog B (S. cerevisiae) 1.497
H3C7 H3 clustered histone 7 1.494
LTN1 listerin E3 ubiquitin protein ligase 1 1.493
STX17 syntaxin 17 1.492
EEA1 early endosome antigen 1 1.489
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 1.489
CUL3 cullin 3 1.487
H3-7 H3.7 histone (putative) 1.487
H3-5 H3.5 histone 1.486
H3-3B H3.3 histone B 1.486
H3C13 H3 clustered histone 13 1.486
RAB5A RAB5A, member RAS oncogene family 1.485
H3-4 H3.4 histone, cluster member 1.485
CDPF1 cysteine-rich, DPF motif domain containing 1 1.482
CTRB2 chymotrypsinogen B2 1.48
HSF1 heat shock transcription factor 1 1.478
BAG5 BCL2-associated athanogene 5 1.478
UBE2L3 ubiquitin-conjugating enzyme E2L 3 1.477
CTRB1 chymotrypsinogen B1 1.476
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 1.472
HOOK3 hook microtubule-tethering protein 3 1.472
GSK3B glycogen synthase kinase 3 beta 1.462
UBC ubiquitin C 1.462
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 1.462
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.462
RHOD ras homolog family member D 1.459
UBE4B ubiquitination factor E4B 1.457
PML promyelocytic leukemia 1.456
ATG4B autophagy related 4B, cysteine peptidase 1.455
TRIM21 tripartite motif containing 21 1.451
ZFYVE1 zinc finger, FYVE domain containing 1 1.451
EP300 E1A binding protein p300 1.449
KAT2B K(lysine) acetyltransferase 2B 1.446
SSBP2 single-stranded DNA binding protein 2 1.445
EPS15 epidermal growth factor receptor pathway substrate 15 1.443
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 1.443
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.442
SLAMF7 SLAM family member 7 1.442
CCND1 cyclin D1 1.442
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 1.439
FOXO3 forkhead box O3 1.439
BRCA1 breast cancer 1, early onset 1.439
SYNPO2 synaptopodin 2 1.438
CRYAB crystallin, alpha B 1.438
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.436
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.431
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.431
USP8 ubiquitin specific peptidase 8 1.425
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.42
PSME4 proteasome (prosome, macropain) activator subunit 4 1.42
ELOVL4 ELOVL fatty acid elongase 4 1.418
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 1.408
INS insulin 1.402
HSPA1A heat shock 70kDa protein 1A 1.401
SIRT6 sirtuin 6 1.401
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.401
EDC4 enhancer of mRNA decapping 4 1.4
BIRC5 baculoviral IAP repeat containing 5 1.4
CUL1 cullin 1 1.399
SDC1 syndecan 1 1.397
SEL1L sel-1 suppressor of lin-12-like (C. elegans) 1.395
UBXN6 UBX domain protein 6 1.39
CYLD cylindromatosis (turban tumor syndrome) 1.388
IGF1 insulin-like growth factor 1 (somatomedin C) 1.385
CDK5 cyclin-dependent kinase 5 1.385
PEPD peptidase D 1.384
TRIM25 tripartite motif containing 25 1.383
RBX1 ring-box 1, E3 ubiquitin protein ligase 1.382
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.382
CCNL2 cyclin L2 1.38
TCHP trichoplein, keratin filament binding 1.379
CDKN2A cyclin-dependent kinase inhibitor 2A 1.379
VDAC1 voltage-dependent anion channel 1 1.377
CD38 CD38 molecule 1.376
UBE2D1 ubiquitin-conjugating enzyme E2D 1 1.374
RAD50 RAD50 homolog (S. cerevisiae) 1.374
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.372
NCOR1 nuclear receptor corepressor 1 1.372
CFLAR CASP8 and FADD-like apoptosis regulator 1.37
TGFB1 transforming growth factor, beta 1 1.367
RHEB Ras homolog enriched in brain 1.366
SEPTIN5 septin 5 1.366
UFM1 ubiquitin-fold modifier 1 1.364
TLR4 toll-like receptor 4 1.363
MYOT myotilin 1.362
UBE4A ubiquitination factor E4A 1.361
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.357
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.356
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.355
CD8A CD8a molecule 1.353
RAB11A RAB11A, member RAS oncogene family 1.353
MFN2 mitofusin 2 1.352
USP32 ubiquitin specific peptidase 32 1.351
SKP1 S-phase kinase-associated protein 1 1.349
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma 1.348
USP3 ubiquitin specific peptidase 3 1.348
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1.347
TNPO1 transportin 1 1.345
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 1.344
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 1.344
EIF4E eukaryotic translation initiation factor 4E 1.341
NSD2 nuclear receptor binding SET domain protein 2 1.341
DAPK1 death-associated protein kinase 1 1.339
EGF epidermal growth factor 1.339
TH tyrosine hydroxylase 1.338
KRT8 keratin 8, type II 1.338
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) 1.336
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) 1.336
HMOX1 heme oxygenase 1 1.335
TSC2 tuberous sclerosis 2 1.335
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 1.335
TRIM41 tripartite motif containing 41 1.332
MAPK3 mitogen-activated protein kinase 3 1.33
MARCHF6 membrane associated ring-CH-type finger 6 1.33
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.328
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.328
FHIP1B FHF complex subunit HOOK interacting protein 1B 1.324
TOLLIP toll interacting protein 1.323
ATF4 activating transcription factor 4 1.319
IRF4 interferon regulatory factor 4 1.316
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.315
SMG5 SMG5 nonsense mediated mRNA decay factor 1.313
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 1.31
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.309
ERBB2 erb-b2 receptor tyrosine kinase 2 1.308
PDIA3 protein disulfide isomerase family A, member 3 1.304
FUNDC1 FUN14 domain containing 1 1.303
BAG2 BCL2-associated athanogene 2 1.301
ATN1 atrophin 1 1.299
NIN ninein (GSK3B interacting protein) 1.299
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 1.298
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) 1.297
GOLGA2 golgin A2 1.296
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.295
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.293
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.293
MUL1 mitochondrial E3 ubiquitin protein ligase 1 1.293
ATG9A autophagy related 9A 1.292
E2F1 E2F transcription factor 1 1.292
ATAT1 alpha tubulin acetyltransferase 1 1.289
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.288
BDNF brain-derived neurotrophic factor 1.288
COPS5 COP9 signalosome subunit 5 1.286
TRIM32 tripartite motif containing 32 1.285
IAPP islet amyloid polypeptide 1.284
STAMBP STAM binding protein 1.283
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 1.283
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 1.283
PABPC1 poly(A) binding protein, cytoplasmic 1 1.283
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 1.282
KAT5 K(lysine) acetyltransferase 5 1.281
CD4 CD4 molecule 1.281
UBE2I ubiquitin-conjugating enzyme E2I 1.279
IFNB1 interferon, beta 1, fibroblast 1.276
LMNA lamin A/C 1.276
TRIM16 tripartite motif containing 16 1.276
UBE2E2 ubiquitin-conjugating enzyme E2E 2 1.276
HSPA6 heat shock 70kDa protein 6 (HSP70B') 1.276
PLAA phospholipase A2-activating protein 1.275
XRN1 5'-3' exoribonuclease 1 1.274
RIGI RNA sensor RIG-I 1.273
ULK2 unc-51 like autophagy activating kinase 2 1.272
POMP proteasome maturation protein 1.271
USP30 ubiquitin specific peptidase 30 1.27
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1 1.269
SRRD SRR1 domain containing 1.268
NLRP3 NLR family, pyrin domain containing 3 1.267
MYOM2 myomesin 2 1.265
TRIM11 tripartite motif containing 11 1.265
CTSS cathepsin S 1.264
MFN1 mitofusin 1 1.263
USP15 ubiquitin specific peptidase 15 1.261
UBR4 ubiquitin protein ligase E3 component n-recognin 4 1.261
RAB1A RAB1A, member RAS oncogene family 1.261
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.259
ATXN7 ataxin 7 1.259
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 1.258
ZC3H14 zinc finger CCCH-type containing 14 1.257
ESR1 estrogen receptor 1 1.257
USP1 ubiquitin specific peptidase 1 1.257
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 1.256
CHUK conserved helix-loop-helix ubiquitous kinase 1.256
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 1.255
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 1.255
JAK2 Janus kinase 2 1.253
BACE1 beta-site APP-cleaving enzyme 1 1.252
IRF3 interferon regulatory factor 3 1.25
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 1.249
CDK1 cyclin-dependent kinase 1 1.249
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.245
RNASE3 ribonuclease, RNase A family, 3 1.244
USP19 ubiquitin specific peptidase 19 1.243
CREBBP CREB binding protein 1.241
UBE2W ubiquitin-conjugating enzyme E2W (putative) 1.238
UBXN4 UBX domain protein 4 1.237
FOXO1 forkhead box O1 1.236
ITCH itchy E3 ubiquitin protein ligase 1.235
RAB8A RAB8A, member RAS oncogene family 1.235
MAVS mitochondrial antiviral signaling protein 1.235
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.231
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8 1.23
UXT ubiquitously-expressed, prefoldin-like chaperone 1.228
SVIP small VCP/p97-interacting protein 1.227
RNF181 ring finger protein 181 1.226
TRIM23 tripartite motif containing 23 1.225
SIRT3 sirtuin 3 1.224
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 1.223
APAF1 apoptotic peptidase activating factor 1 1.222
H2BC21 H2B clustered histone 21 1.222
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.221
UBXN1 UBX domain protein 1 1.22
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.219
FAF2 Fas associated factor family member 2 1.219
TGM2 transglutaminase 2 1.217
TRIM17 tripartite motif containing 17 1.217
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.215
DNM1L dynamin 1-like 1.214
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) 1.213
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 1.212
KAT2A K(lysine) acetyltransferase 2A 1.211
SYVN1 synovial apoptosis inhibitor 1, synoviolin 1.211
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 1.21
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 1.209
MYH14 myosin, heavy chain 14, non-muscle 1.207
HTRA2 HtrA serine peptidase 2 1.207
FKBP8 FK506 binding protein 8, 38kDa 1.207
UBE3C ubiquitin protein ligase E3C 1.206
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 1.205
TRIM28 tripartite motif containing 28 1.205
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.203
RING1 ring finger protein 1 1.202
H4C7 H4 clustered histone 7 1.202
DAXX death-domain associated protein 1.2
SIAH1 siah E3 ubiquitin protein ligase 1 1.198
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 1.198
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 1.198
RNF4 ring finger protein 4 1.194
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.193
UBE2G2 ubiquitin-conjugating enzyme E2G 2 1.193
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.193
GBA1 glucosylceramidase beta 1 1.193
SIAH2 siah E3 ubiquitin protein ligase 2 1.192
RAD23A RAD23 homolog A (S. cerevisiae) 1.192
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 1.191
CTSB cathepsin B 1.19
PNRC2 proline-rich nuclear receptor coactivator 2 1.189
CHEK1 checkpoint kinase 1 1.189
TUBA4A tubulin, alpha 4a 1.187
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 1.186
RPTOR regulatory associated protein of MTOR, complex 1 1.183
PHGDH phosphoglycerate dehydrogenase 1.181
USP2 ubiquitin specific peptidase 2 1.181
MAPK8 mitogen-activated protein kinase 8 1.179
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1.179
NDEL1 nudE neurodevelopment protein 1-like 1 1.178
UBR5 ubiquitin protein ligase E3 component n-recognin 5 1.178
CLU clusterin 1.178
RUBCN rubicon autophagy regulator 1.178
ECPAS Ecm29 proteasome adaptor and scaffold 1.177
TCP1 t-complex 1 1.175
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 1.174
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 1.173
CDC37 cell division cycle 37 1.172
CDK4 cyclin-dependent kinase 4 1.169
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 1.168
NGLY1 N-glycanase 1 1.166
CREB1 cAMP responsive element binding protein 1 1.165
MYD88 myeloid differentiation primary response 88 1.163
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 1.162
IGF1R insulin-like growth factor 1 receptor 1.16
UBE2E3 ubiquitin-conjugating enzyme E2E 3 1.16
GOLGB1 golgin B1 1.157
BICD1 bicaudal D homolog 1 (Drosophila) 1.157
KDM1A lysine (K)-specific demethylase 1A 1.156
USP11 ubiquitin specific peptidase 11 1.156
USP36 ubiquitin specific peptidase 36 1.154
TXNDC8 thioredoxin domain containing 8 (spermatozoa) 1.152
SOD2 superoxide dismutase 2, mitochondrial 1.151
FLNC filamin C, gamma 1.151
CUL4B cullin 4B 1.151
RTL10 retrotransposon Gag like 10 1.15
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 1.149
UBA5 ubiquitin-like modifier activating enzyme 5 1.148
CSTB cystatin B (stefin B) 1.148
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 1.148
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 1.147
SNAP29 synaptosomal-associated protein, 29kDa 1.147
YOD1 YOD1 deubiquitinase 1.147
FBL fibrillarin 1.145
PRKDC protein kinase, DNA-activated, catalytic polypeptide 1.145
LMNB1 lamin B1 1.145
SIRT7 sirtuin 7 1.145
HSPB9 heat shock protein, alpha-crystallin-related, B9 1.143
STAT1 signal transducer and activator of transcription 1, 91kDa 1.139
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 1.136
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.136
RPL11 ribosomal protein L11 1.135
PSEN2 presenilin 2 1.134
RUVBL1 RuvB-like AAA ATPase 1 1.133
UBR2 ubiquitin protein ligase E3 component n-recognin 2 1.131
UBQLNL ubiquilin-like 1.128
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.128
CXCL8 chemokine (C-X-C motif) ligand 8 1.125
PHF1 PHD finger protein 1 1.124
ATG4D autophagy related 4D, cysteine peptidase 1.124
TRIM37 tripartite motif containing 37 1.123
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.121
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 1.121
HSPH1 heat shock 105kDa/110kDa protein 1 1.12
FBXO7 F-box protein 7 1.119
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 1.117
CD2 CD2 molecule 1.117
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.117
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.117
RUVBL2 RuvB-like AAA ATPase 2 1.116
DDB1 damage-specific DNA binding protein 1, 127kDa 1.116
CCNA2 cyclin A2 1.115
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.115
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 1.114
RCOR1 REST corepressor 1 1.113
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 1.111
SNAPIN SNAP-associated protein 1.109
TDRD6 tudor domain containing 6 1.105
FYCO1 FYVE and coiled-coil domain containing 1 1.104
TSG101 tumor susceptibility 101 1.104
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.103
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 1.102
FLT3 fms-related tyrosine kinase 3 1.102
SMG7 SMG7 nonsense mediated mRNA decay factor 1.1
GDNF glial cell derived neurotrophic factor 1.099
H2AC20 H2A clustered histone 20 1.098
CALML5 calmodulin-like 5 1.097
H2AC19 H2A clustered histone 19 1.097
USP35 ubiquitin specific peptidase 35 1.096
IL10 interleukin 10 1.096
APOE apolipoprotein E 1.094
CDK2 cyclin-dependent kinase 2 1.093
RETREG1 reticulophagy regulator 1 1.093
PFAS phosphoribosylformylglycinamidine synthase 1.092
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 1.09
TP53BP1 tumor protein p53 binding protein 1 1.089
ELAVL1 ELAV like RNA binding protein 1 1.089
USP20 ubiquitin specific peptidase 20 1.088
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.087
TRIM6-TRIM34 TRIM6-TRIM34 readthrough 1.087
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.087
BCL6 B-cell CLL/lymphoma 6 1.086
CCNA1 cyclin A1 1.085
ATG4C autophagy related 4C, cysteine peptidase 1.085
ATG2B autophagy related 2B 1.085
CALML6 calmodulin-like 6 1.083
CALML4 calmodulin-like 4 1.083
CCPG1 cell cycle progression 1 1.083
CDC34 cell division cycle 34 1.082
TRIM22 tripartite motif containing 22 1.082
CALML3 calmodulin-like 3 1.081
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.081
PFN1 profilin 1 1.081
FN1 fibronectin 1 1.081
CHMP2B charged multivesicular body protein 2B 1.08
ATF5 activating transcription factor 5 1.08
SIRT5 sirtuin 5 1.08
CD274 CD274 molecule 1.08
CFH complement factor H 1.079
IL1A interleukin 1, alpha 1.079
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.079
NGF nerve growth factor (beta polypeptide) 1.078
USP33 ubiquitin specific peptidase 33 1.078
LGALS8 lectin, galactoside-binding, soluble, 8 1.078
TGOLN2 trans-golgi network protein 2 1.077
CCL2 chemokine (C-C motif) ligand 2 1.076
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.074
TLR3 toll-like receptor 3 1.073
NEFL neurofilament, light polypeptide 1.072
RNMT RNA (guanine-7-) methyltransferase 1.072
SMG6 SMG6 nonsense mediated mRNA decay factor 1.071
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 1.07
NCBP1 nuclear cap binding protein subunit 1, 80kDa 1.068
RHOT1 ras homolog family member T1 1.067
TDP2 tyrosyl-DNA phosphodiesterase 2 1.066
STAT5A signal transducer and activator of transcription 5A 1.066
LOC102724652 alpha-crystallin A chain 1.065
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.065
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 1.063
ASB10 ankyrin repeat and SOCS box containing 10 1.063
CAV1 caveolin 1, caveolae protein, 22kDa 1.062
IFNA1 interferon, alpha 1 1.062
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 1.061
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.058
GPX3 glutathione peroxidase 3 1.058
GPX7 glutathione peroxidase 7 1.056
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.055
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.053
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.053
LSM1 LSM1, U6 small nuclear RNA associated 1.053
TENT5C terminal nucleotidyltransferase 5C 1.051
RABIF RAB interacting factor 1.049
PRND prion protein 2 (dublet) 1.048
CUL4A cullin 4A 1.048
P4HB prolyl 4-hydroxylase, beta polypeptide 1.047
MED12 mediator complex subunit 12 1.047
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.045
HDAC7 histone deacetylase 7 1.043
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.043
RPS6 ribosomal protein S6 1.043
NQO1 NAD(P)H dehydrogenase, quinone 1 1.042
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.041
TLR2 toll-like receptor 2 1.041
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.04
IL18 interleukin 18 1.04
PIAS1 protein inhibitor of activated STAT, 1 1.04
ATF3 activating transcription factor 3 1.039
CGAS cyclic GMP-AMP synthase 1.037
TRAF3 TNF receptor-associated factor 3 1.036
TUB tubby bipartite transcription factor 1.036
LITAF lipopolysaccharide-induced TNF factor 1.036
PRDX2 peroxiredoxin 2 1.035
CHEK2 checkpoint kinase 2 1.035
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 1.034
MARCHF7 membrane associated ring-CH-type finger 7 1.034
PDIA4 protein disulfide isomerase family A, member 4 1.032
PLEK2 pleckstrin 2 1.032
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) 1.031
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 1.031
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 1.029
NES nestin 1.029
VAMP8 vesicle-associated membrane protein 8 1.029
GPX2 glutathione peroxidase 2 1.029
PACRG PARK2 co-regulated 1.028
WWP1 WW domain containing E3 ubiquitin protein ligase 1 1.028
DCP2 decapping mRNA 2 1.027
GLB1 galactosidase, beta 1 1.025
BCL2L13 BCL2-like 13 (apoptosis facilitator) 1.024
MORC4 MORC family CW-type zinc finger 4 1.024
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.024
SH2D3C SH2 domain containing 3C 1.023
MID2 midline 2 1.022
SIRT4 sirtuin 4 1.022
PHB2 prohibitin 2 1.022
PLEK pleckstrin 1.022
CPEB1 cytoplasmic polyadenylation element binding protein 1 1.021
HSPE1 heat shock 10kDa protein 1 1.02
DIABLO diablo, IAP-binding mitochondrial protein 1.017
ATG4A autophagy related 4A, cysteine peptidase 1.016
DTNBP1 dystrobrevin binding protein 1 1.015
DCTN4 dynactin 4 (p62) 1.014
FLNA filamin A, alpha 1.014
LGALS4 lectin, galactoside-binding, soluble, 4 1.014
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.014
COPB1 coatomer protein complex, subunit beta 1 1.013
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.012
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.012
ZNF746 zinc finger protein 746 1.011
WDR37 WD repeat domain 37 1.011
VIM vimentin 1.01
MPG N-methylpurine-DNA glycosylase 1.009
CXCR4 chemokine (C-X-C motif) receptor 4 1.007
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 1.007
AUP1 ancient ubiquitous protein 1 1.006
EIF3B eukaryotic translation initiation factor 3, subunit B 1.006
CDKN3 cyclin-dependent kinase inhibitor 3 1.005
MARCHF5 membrane associated ring-CH-type finger 5 1.005
TM9SF4 transmembrane 9 superfamily protein member 4 1.004
SENP1 SUMO1/sentrin specific peptidase 1 1.004
ELOB elongin B 1.004
BIRC2 baculoviral IAP repeat containing 2 1.003
ATG9B autophagy related 9B 1.003
GPX5 glutathione peroxidase 5 1.002
GPX8 glutathione peroxidase 8 (putative) 1.002
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.001
CAPN1 calpain 1, (mu/I) large subunit 1.001
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 1.0
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.999
CNOT4 CCR4-NOT transcription complex, subunit 4 0.998
CEP131 centrosomal protein 131kDa 0.998
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.996
RPS27A ribosomal protein S27a 0.994
FBXO2 F-box protein 2 0.992
PIAS4 protein inhibitor of activated STAT, 4 0.99
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.99
APEH acylaminoacyl-peptide hydrolase 0.988
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.987
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.987
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 0.985
RBM8A RNA binding motif protein 8A 0.984
GPX6 glutathione peroxidase 6 0.984
CNTLN centlein, centrosomal protein 0.983
RNF126 ring finger protein 126 0.982
TWSG1 twisted gastrulation BMP signaling modulator 1 0.982
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.982
SLAMF1 signaling lymphocytic activation molecule family member 1 0.982
TXNDC9 thioredoxin domain containing 9 0.98
TEX264 testis expressed 264 0.98
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 0.977
CFL2 cofilin 2 (muscle) 0.977
CSNK1A1 casein kinase 1, alpha 1 0.976
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 0.976
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.976
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.975
RHOA ras homolog family member A 0.974
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.973
H2AX H2A.X variant histone 0.971
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.97
TPP2 tripeptidyl peptidase II 0.969
TUBA1A tubulin, alpha 1a 0.968
PPARG peroxisome proliferator-activated receptor gamma 0.966
FASLG Fas ligand (TNF superfamily, member 6) 0.966
MARCKS myristoylated alanine-rich protein kinase C substrate 0.965
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 0.965
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.964
NDE1 nudE neurodevelopment protein 1 0.963
SH3GL3 SH3-domain GRB2-like 3 0.963
SYNGAP1 synaptic Ras GTPase activating protein 1 0.963
NAE1 NEDD8 activating enzyme E1 subunit 1 0.962
RANBP9 RAN binding protein 9 0.961
ATXN10 ataxin 10 0.96
RTN3 reticulon 3 0.96
RAB10 RAB10, member RAS oncogene family 0.96
GOLGA3 golgin A3 0.96
RAD51 RAD51 recombinase 0.959
LATS1 large tumor suppressor kinase 1 0.959
CASP6 caspase 6, apoptosis-related cysteine peptidase 0.959
SYN1 synapsin I 0.958
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.956
TRIM9 tripartite motif containing 9 0.956
MRPS33 mitochondrial ribosomal protein S33 0.956
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 0.954
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.953
ERVW-1 endogenous retrovirus group W, member 1 0.953
SPART spartin 0.953
GOPC golgi-associated PDZ and coiled-coil motif containing 0.952
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.951
USP26 ubiquitin specific peptidase 26 0.95
UNC45B unc-45 homolog B (C. elegans) 0.949
ACTA1 actin, alpha 1, skeletal muscle 0.947
TMLHE trimethyllysine hydroxylase, epsilon 0.947
MAP1LC3B2 microtubule-associated protein 1 light chain 3 beta 2 0.945
TUBA1C tubulin, alpha 1c 0.945
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.945
EGLN3 egl-9 family hypoxia-inducible factor 3 0.944
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.944
CRYGS crystallin, gamma S 0.943
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.942
EGR1 early growth response 1 0.942
PARL presenilin associated, rhomboid-like 0.942
MATR3 matrin 3 0.939
CCND2 cyclin D2 0.939
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.938
RICTOR RPTOR independent companion of MTOR, complex 2 0.938
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 0.938
UBE2M ubiquitin-conjugating enzyme E2M 0.937
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.937
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 0.936
TFRC transferrin receptor 0.936
DRAM1 DNA-damage regulated autophagy modulator 1 0.936
ZRANB1 zinc finger, RAN-binding domain containing 1 0.936
AGO2 argonaute RISC catalytic component 2 0.934
SOX2 SRY (sex determining region Y)-box 2 0.934
CDK6 cyclin-dependent kinase 6 0.934
CNTRL centriolin 0.934
MAP2K1 mitogen-activated protein kinase kinase 1 0.933
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.932
POLI polymerase (DNA directed) iota 0.932
STK11 serine/threonine kinase 11 0.931
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11 0.93
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 0.929
CCDC82 coiled-coil domain containing 82 0.928
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.926
ZBED5 zinc finger, BED-type containing 5 0.926
SH3PXD2B SH3 and PX domains 2B 0.926
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.925
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.925
SACS sacsin molecular chaperone 0.925
BECN2 beclin 2 0.924
KLHL20 kelch-like family member 20 0.924
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.924
RNF135 ring finger protein 135 0.923
ERP44 endoplasmic reticulum protein 44 0.923
GPSM1 G-protein signaling modulator 1 0.923
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.921
PCNA proliferating cell nuclear antigen 0.92
CD44 CD44 molecule (Indian blood group) 0.917
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.916
PCM1 pericentriolar material 1 0.916
AURKB aurora kinase B 0.916
NPC1 Niemann-Pick disease, type C1 0.913
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.913
CTSL cathepsin L 0.912
PLK1 polo-like kinase 1 0.912
HLA-F major histocompatibility complex, class I, F 0.91
UBE2E1 ubiquitin-conjugating enzyme E2E 1 0.91
DCTN3 dynactin 3 (p22) 0.909
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 0.909
CUL2 cullin 2 0.909
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.908
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.907
TMC6 transmembrane channel-like 6 0.907
UBA7 ubiquitin-like modifier activating enzyme 7 0.907
BIRC3 baculoviral IAP repeat containing 3 0.907
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 0.907
SESN2 sestrin 2 0.905
EPN1 epsin 1 0.905
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.905
SYT12 synaptotagmin XII 0.905
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.904
FGF13 fibroblast growth factor 13 0.902
LGALS3 lectin, galactoside-binding, soluble, 3 0.902
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.902
MARCHF2 membrane associated ring-CH-type finger 2 0.901
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.9
TPMT thiopurine S-methyltransferase 0.899
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.899
KRT18 keratin 18, type I 0.897
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.897
SFTPC surfactant protein C 0.896
TLR7 toll-like receptor 7 0.896
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.895
GOLGA1 golgin A1 0.894
FADD Fas (TNFRSF6)-associated via death domain 0.893
HDAC5 histone deacetylase 5 0.892
TXNRD1 thioredoxin reductase 1 0.892
SLC30A2 solute carrier family 30 (zinc transporter), member 2 0.891
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.891
AGFG1 ArfGAP with FG repeats 1 0.888
B2M beta-2-microglobulin 0.887
CD63 CD63 molecule 0.887
OTUD1 OTU deubiquitinase 1 0.887
BCL2L2 BCL2-like 2 0.886
IL2 interleukin 2 0.886
PFDN5 prefoldin subunit 5 0.885
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.885
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 0.884
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.884
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 0.884
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.883
SOCS1 suppressor of cytokine signaling 1 0.882
TRAP1 TNF receptor-associated protein 1 0.881
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 0.879
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.878
LRPPRC leucine-rich pentatricopeptide repeat containing 0.878
CDK9 cyclin-dependent kinase 9 0.878
ATXN7L2 ataxin 7-like 2 0.877
TBP TATA box binding protein 0.877
LAP3 leucine aminopeptidase 3 0.876
DDIT4 DNA-damage-inducible transcript 4 0.874
USP18 ubiquitin specific peptidase 18 0.874
RARA retinoic acid receptor, alpha 0.874
IFIH1 interferon induced with helicase C domain 1 0.874
PGK1 phosphoglycerate kinase 1 0.873
GRK1 G protein-coupled receptor kinase 1 0.873
PKM pyruvate kinase, muscle 0.872
ATXN7L1 ataxin 7-like 1 0.872
RBM12 RNA binding motif protein 12 0.872
CD40 CD40 molecule, TNF receptor superfamily member 5 0.872
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.872
BRD4 bromodomain containing 4 0.871
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.871
EIF4A1 eukaryotic translation initiation factor 4A1 0.871
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.871
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.871
AGXT alanine-glyoxylate aminotransferase 0.87
WDR48 WD repeat domain 48 0.87
USP24 ubiquitin specific peptidase 24 0.87
PRKD1 protein kinase D1 0.869
BIRC6 baculoviral IAP repeat containing 6 0.869
RASD1 RAS, dexamethasone-induced 1 0.869
TTR transthyretin 0.869
MAPK13 mitogen-activated protein kinase 13 0.868
FAF1 Fas (TNFRSF6) associated factor 1 0.868
CDC42 cell division cycle 42 0.868
TUBA3E tubulin, alpha 3e 0.868
DEPTOR DEP domain containing MTOR-interacting protein 0.868
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.867
RAB29 RAB29, member RAS oncogene family 0.867
RUSC1 RUN and SH3 domain containing 1 0.866
LMAN1 lectin, mannose-binding, 1 0.866
TUBAL3 tubulin, alpha-like 3 0.865
ODF1 outer dense fiber of sperm tails 1 0.864
PSAT1 phosphoserine aminotransferase 1 0.863
NUP214 nucleoporin 214kDa 0.861
MARK4 MAP/microtubule affinity-regulating kinase 4 0.86
BCL2L10 BCL2-like 10 (apoptosis facilitator) 0.86
HMGB1 high mobility group box 1 0.859
GLYATL1 glycine-N-acyltransferase-like 1 0.858
MAPK14 mitogen-activated protein kinase 14 0.858
TFAM transcription factor A, mitochondrial 0.857
NEFH neurofilament, heavy polypeptide 0.856
USP28 ubiquitin specific peptidase 28 0.856
NOD2 nucleotide-binding oligomerization domain containing 2 0.855
PEX5 peroxisomal biogenesis factor 5 0.855
MAPK1 mitogen-activated protein kinase 1 0.854
DAPK3 death-associated protein kinase 3 0.852
NEXN nexilin (F actin binding protein) 0.851
HIPK2 homeodomain interacting protein kinase 2 0.85
DAPK2 death-associated protein kinase 2 0.85
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.85
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 0.85
BAG6 BCL2-associated athanogene 6 0.85
ATL3 atlastin GTPase 3 0.85
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.85
GET3 guided entry of tail-anchored proteins factor 3, ATPase 0.85
FMR1 fragile X mental retardation 1 0.848
AURKA aurora kinase A 0.848
SUMO4 small ubiquitin-like modifier 4 0.848
RNF31 ring finger protein 31 0.847
FOXO4 forkhead box O4 0.846
GIGYF2 GRB10 interacting GYF protein 2 0.846
MAP2K7 mitogen-activated protein kinase kinase 7 0.845
GSR glutathione reductase 0.845
SENP8 SUMO/sentrin specific peptidase family member 8 0.843
IRGM immunity-related GTPase family, M 0.842
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.84
BIK BCL2-interacting killer (apoptosis-inducing) 0.84
METAP2 methionyl aminopeptidase 2 0.84
NFE2 nuclear factor, erythroid 2 0.839
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.839
STAMBPL1 STAM binding protein-like 1 0.838
STAT5B signal transducer and activator of transcription 5B 0.837
MAPK11 mitogen-activated protein kinase 11 0.837
PRKD3 protein kinase D3 0.836
LMBR1 limb development membrane protein 1 0.835
PEX2 peroxisomal biogenesis factor 2 0.835
NANOG Nanog homeobox 0.834
TRIM27 tripartite motif containing 27 0.834
CCNF cyclin F 0.834
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.834
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.833
ANK2 ankyrin 2, neuronal 0.833
LSMEM2 leucine-rich single-pass membrane protein 2 0.832
GZMM granzyme M (lymphocyte met-ase 1) 0.831
DEPP1 DEPP autophagy regulator 1 0.831
ICAM1 intercellular adhesion molecule 1 0.83
SNAI1 snail family zinc finger 1 0.83
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 0.829
RUNX2 runt-related transcription factor 2 0.829
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.828
UBXN2A UBX domain protein 2A 0.828
CLCN7 chloride channel, voltage-sensitive 7 0.827
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.827
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.826
ELP3 elongator acetyltransferase complex subunit 3 0.825
EEF2 eukaryotic translation elongation factor 2 0.825
CD47 CD47 molecule 0.825
GADD45A growth arrest and DNA-damage-inducible, alpha 0.824
BANF1 barrier to autointegration factor 1 0.824
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.824
UBE2H ubiquitin-conjugating enzyme E2H 0.824
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.823
JAK1 Janus kinase 1 0.823
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.823
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.822
FYN FYN proto-oncogene, Src family tyrosine kinase 0.822
RO60 Ro60, Y RNA binding protein 0.822
TUBA3D tubulin, alpha 3d 0.821
TOPBP1 topoisomerase (DNA) II binding protein 1 0.821
ELANE elastase, neutrophil expressed 0.82
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.82
TUBA8 tubulin, alpha 8 0.817
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.817
IDE insulin-degrading enzyme 0.817
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.816
AXIN1 axin 1 0.816
UBE2O ubiquitin-conjugating enzyme E2O 0.816
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.816
RASD2 RASD family, member 2 0.814
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.813
CD34 CD34 molecule 0.813
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.813
ATF7IP activating transcription factor 7 interacting protein 0.812
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 0.811
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.811
FLNB filamin B, beta 0.811
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.811
PRDX1 peroxiredoxin 1 0.811
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.81
POU5F1 POU class 5 homeobox 1 0.81
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.81
CCNB1 cyclin B1 0.81
SYP synaptophysin 0.809
MEFV Mediterranean fever 0.809
TRIM14 tripartite motif containing 14 0.808
GCG glucagon 0.808