Aggressive Periodontitis, Generalized Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1719495
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Genes

53 genes associated with the disease Aggressive Periodontitis, Generalized in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
APOE apolipoprotein E
BCHE butyrylcholinesterase
CAMP cathelicidin antimicrobial peptide
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CTSC cathepsin C
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEFB1 defensin, beta 1
GCFC2 GC-rich sequence DNA-binding factor 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
IFNL1 interferon, lambda 1
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL37 interleukin 37
IL4 interleukin 4
IL6 interleukin 6
IL9 interleukin 9
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
LRP5 low density lipoprotein receptor-related protein 5
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
NLRP2 NLR family, pyrin domain containing 2
NLRP3 NLR family, pyrin domain containing 3
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
PLAT plasminogen activator, tissue
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RGS6 regulator of G-protein signaling 6
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLURP1 secreted LY6/PLAUR domain containing 1
SOD2 superoxide dismutase 2, mitochondrial
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor