Airway Disease Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0699949
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Genes

194 genes associated with the disease Airway Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTB actin, beta
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANO1 anoctamin 1, calcium activated chloride channel
APOE apolipoprotein E
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARRB2 arrestin, beta 2
ATF3 activating transcription factor 3
ATF6 activating transcription factor 6
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
AVP arginine vasopressin
BDNF brain-derived neurotrophic factor
BPI bactericidal/permeability-increasing protein
BPIFA1 BPI fold containing family A, member 1
C3 complement component 3
CA12 carbonic anhydrase XII
CAV1 caveolin 1, caveolae protein, 22kDa
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCN2 cellular communication network factor 2
CCR1 chemokine (C-C motif) receptor 1
CCR3 chemokine (C-C motif) receptor 3
CCR8 chemokine (C-C motif) receptor 8
CD163 CD163 molecule
CD1D CD1d molecule
CD28 CD28 molecule
CD300LF CD300 molecule-like family member f
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIA chitinase, acidic
CIRBP cold inducible RNA binding protein
CLCA1 chloride channel accessory 1
CLOCK clock circadian regulator
COX2
CST9 cystatin 9 (testatin)
CTH cystathionine gamma-lyase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
DLL4 delta-like 4 (Drosophila)
DNER delta/notch-like EGF repeat containing
DUSP1 dual specificity phosphatase 1
EBI3 Epstein-Barr virus induced 3
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EHF ets homologous factor
ERN2 endoplasmic reticulum to nucleus signaling 2
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FEV FEV (ETS oncogene family)
FFAR1 free fatty acid receptor 1
FGFR4 fibroblast growth factor receptor 4
FLG filaggrin
FOXO1 forkhead box O1
FOXP3 forkhead box P3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GIMAP5 GTPase, IMAP family member 5
GJA1 gap junction protein, alpha 1, 43kDa
GORASP1 golgi reassembly stacking protein 1, 65kDa
HAS2 hyaluronan synthase 2
HDAC2 histone deacetylase 2
HDAC9 histone deacetylase 9
HDC histidine decarboxylase
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HRH1 histamine receptor H1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IFNL2 interferon, lambda 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL10 interleukin 10
IL13 interleukin 13
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL17A interleukin 17A
IL17F interleukin 17F
IL17RB interleukin 17 receptor B
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL20 interleukin 20
IL22 interleukin 22
IL25 interleukin 25
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL9 interleukin 9
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK1 Janus kinase 1
KLF2 Kruppel-like factor 2
LAMB1 laminin, beta 1
LGALS1 lectin, galactoside-binding, soluble, 1
LTB lymphotoxin beta (TNF superfamily, member 3)
LTB4R2 leukotriene B4 receptor 2
MAPK13 mitogen-activated protein kinase 13
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MMP1 matrix metallopeptidase 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYDGF myeloid-derived growth factor
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NOTCH2 notch 2
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PARP14 poly (ADP-ribose) polymerase family, member 14
PCLAF PCNA clamp associated factor
PCNA proliferating cell nuclear antigen
PDCD1LG2 programmed cell death 1 ligand 2
PDE4A phosphodiesterase 4A, cAMP-specific
PDE5A phosphodiesterase 5A, cGMP-specific
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRRT2 proline-rich transmembrane protein 2
PTAFR platelet-activating factor receptor
PTGDR2 prostaglandin D2 receptor 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPA protein phosphatase 2 phosphatase activator
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS2 regulator of G-protein signaling 2
RNASE3 ribonuclease, RNase A family, 3
RXFP1 relaxin/insulin-like family peptide receptor 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB3A2 secretoglobin, family 3A, member 2
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SFTPC surfactant protein C
SFTPD surfactant protein D
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC26A9 solute carrier family 26 (anion exchanger), member 9
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SOD1 superoxide dismutase 1, soluble
SPP1 secreted phosphoprotein 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYT1 synaptotagmin I
SYTL3 synaptotagmin-like 3
TAS2R38 taste receptor, type 2, member 38
TGFB1 transforming growth factor, beta 1
TICAM1 toll-like receptor adaptor molecule 1
TIPE2 TNF alpha induced protein 8 like 2
TLR4 toll-like receptor 4
TMPRSS11D transmembrane protease, serine 11D
TNF tumor necrosis factor
TNNI3 troponin I type 3 (cardiac)
TREM1 triggering receptor expressed on myeloid cells 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSLP thymic stromal lymphopoietin
TYROBP TYRO protein tyrosine kinase binding protein
VEGFA vascular endothelial growth factor A
WNK1 WNK lysine deficient protein kinase 1