| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aliskiren perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aliskiren_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSAMP | limbic system-associated membrane protein | 0.0816321 |
| FMN1 | formin 1 | 0.0726859 |
| VCL | vinculin | 0.0664394 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0630136 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0592699 |
| DPH6 | diphthamine biosynthesis 6 | 0.0579871 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0538826 |
| SMYD3 | SET and MYND domain containing 3 | 0.0528936 |
| TLE4 | transducin-like enhancer of split 4 | 0.0518465 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0466066 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0407971 |
| MEIS2 | Meis homeobox 2 | 0.0392132 |
| ASPH | aspartate beta-hydroxylase | 0.0386889 |
| HELZ | helicase with zinc finger | 0.0368927 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0339462 |
| INTS6 | integrator complex subunit 6 | 0.0336043 |
| TENM4 | teneurin transmembrane protein 4 | 0.0334224 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0334221 |
| NREP | neuronal regeneration related protein | 0.0311272 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0302896 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.029923 |
| MSI2 | musashi RNA-binding protein 2 | 0.0294036 |
| DST | dystonin | 0.0293471 |
| PRKCA | protein kinase C, alpha | 0.0288787 |
| SEPTIN9 | septin 9 | 0.028475 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0284685 |
| ATXN1 | ataxin 1 | 0.0284654 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0274643 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0272606 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0272388 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0271399 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0266457 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.026619 |
| ZNF638 | zinc finger protein 638 | 0.0262731 |
| AUTS2 | autism susceptibility candidate 2 | 0.025907 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0253771 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0252844 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0250508 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.025013 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0247784 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0244351 |
| THBS1 | thrombospondin 1 | 0.0241721 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0234264 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.023334 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0227371 |
| LPIN1 | lipin 1 | 0.0226207 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0225936 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0225831 |
| DNMBP | dynamin binding protein | 0.022418 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0223408 |
| SMAD3 | SMAD family member 3 | 0.0221257 |
| FERMT2 | fermitin family member 2 | 0.0221064 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0220724 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0216814 |
| EXOC4 | exocyst complex component 4 | 0.0216504 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0213687 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0210005 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0209651 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0207217 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0206251 |
| VMP1 | vacuole membrane protein 1 | 0.020482 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0201395 |
| EFNA5 | ephrin-A5 | 0.0198396 |
| CADM2 | cell adhesion molecule 2 | 0.0197872 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0192002 |
| HDAC8 | histone deacetylase 8 | 0.0191333 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0190442 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0187117 |
| AEBP2 | AE binding protein 2 | 0.0186007 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0181008 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0180484 |
| HOMER1 | homer scaffolding protein 1 | 0.0178978 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0178685 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0178052 |
| DACH2 | dachshund family transcription factor 2 | 0.0177349 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0175357 |
| ZNF609 | zinc finger protein 609 | 0.0173091 |
| CENPF | centromere protein F, 350/400kDa | 0.0172795 |
| MCL1 | myeloid cell leukemia 1 | 0.0172794 |
| PCNX2 | pecanex 2 | 0.017252 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0171243 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0169598 |
| ANO6 | anoctamin 6 | 0.0169316 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.016507 |
| CFDP1 | craniofacial development protein 1 | 0.0163501 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0161219 |
| ENAH | enabled homolog (Drosophila) | 0.0160858 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0159397 |
| UBXN7 | UBX domain protein 7 | 0.0158549 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0156834 |
| AHR | aryl hydrocarbon receptor | 0.0154214 |
| RAD51B | RAD51 paralog B | 0.0154066 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | 0.0153371 |
| FHIT | fragile histidine triad | 0.0153301 |
| BPTF | bromodomain PHD finger transcription factor | 0.0152681 |
| ITGA1 | integrin, alpha 1 | 0.0152067 |
| MED13L | mediator complex subunit 13-like | 0.0152026 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0150953 |
| IPO9 | importin 9 | 0.015085 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0150626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.247887 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.103201 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0498178 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.043133 |
| VIM | vimentin | -0.0419418 |
| RPS6 | ribosomal protein S6 | -0.037367 |
| FRMD4A | FERM domain containing 4A | -0.0334243 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0283674 |
| RPL19 | ribosomal protein L19 | -0.0268086 |
| COL1A1 | collagen, type I, alpha 1 | -0.0265332 |
| COL3A1 | collagen, type III, alpha 1 | -0.0254751 |
| B2M | beta-2-microglobulin | -0.0237324 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0231946 |
| PTMA | prothymosin, alpha | -0.0230319 |
| NEK7 | NIMA-related kinase 7 | -0.0225804 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0223074 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0221874 |
| KPNB1 | karyopherin (importin) beta 1 | -0.02213 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0219229 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0210757 |
| PDE10A | phosphodiesterase 10A | -0.0204863 |
| RPS24 | ribosomal protein S24 | -0.0203168 |
| SETD5 | SET domain containing 5 | -0.0197726 |
| NRG1 | neuregulin 1 | -0.0195051 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0189541 |
| RPLP0 | ribosomal protein, large, P0 | -0.0189272 |
| WDR43 | WD repeat domain 43 | -0.0179724 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0178047 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0176871 |
| WDR45B | WD repeat domain 45B | -0.0176145 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0168894 |
| FAM107B | family with sequence similarity 107, member B | -0.0168763 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0167926 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0166009 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0163557 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0162472 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0159705 |
| RPL11 | ribosomal protein L11 | -0.015964 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0157897 |
| RPS8 | ribosomal protein S8 | -0.0156803 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0152982 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0152464 |
| ZNF33A | zinc finger protein 33A | -0.0152315 |
| YTHDC1 | YTH domain containing 1 | -0.0149851 |
| RPL35A | ribosomal protein L35a | -0.0149141 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0147784 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0147765 |
| EDNRA | endothelin receptor type A | -0.0147358 |
| KLHL13 | kelch-like family member 13 | -0.0147093 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0147037 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.014536 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0145347 |
| RACK1 | receptor for activated C kinase 1 | -0.014513 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0141352 |
| RPL26 | ribosomal protein L26 | -0.0140831 |
| MTPN | myotrophin | -0.0138987 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0137939 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.013609 |
| SP100 | SP100 nuclear antigen | -0.0135633 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0134431 |
| H1-0 | H1.0 linker histone | -0.0133096 |
| STOX2 | storkhead box 2 | -0.0131327 |
| TMEM123 | transmembrane protein 123 | -0.0130426 |
| RPL34 | ribosomal protein L34 | -0.0129785 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0129293 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0128805 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0128425 |
| ASTN2 | astrotactin 2 | -0.0127755 |
| TRIM37 | tripartite motif containing 37 | -0.0127376 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0127228 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0126726 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0125856 |
| ZFR | zinc finger RNA binding protein | -0.0125735 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0125734 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0124468 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.0123815 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0123719 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0123174 |
| PDCD10 | programmed cell death 10 | -0.0122401 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0122074 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0122022 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0121303 |
| IER3 | immediate early response 3 | -0.0121302 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0120861 |
| MAP1B | microtubule-associated protein 1B | -0.0120526 |
| RPS5 | ribosomal protein S5 | -0.0120415 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0118417 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.011824 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0117768 |
| RPS27 | ribosomal protein S27 | -0.0115598 |
| CCNL1 | cyclin L1 | -0.0115097 |
| S100A6 | S100 calcium binding protein A6 | -0.0113783 |
| TRAPPC8 | trafficking protein particle complex 8 | -0.0113343 |
| RPL37 | ribosomal protein L37 | -0.0113304 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0113007 |
| ENO1 | enolase 1, (alpha) | -0.0112574 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0111919 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0110948 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0110238 |
| CLINT1 | clathrin interactor 1 | -0.0109671 |
