| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Aliskiren perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Aliskiren_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0652201 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0643869 |
| HMGA2 | high mobility group AT-hook 2 | 0.0606188 |
| POTEF | POTE ankyrin domain family, member F | 0.0565423 |
| MT2A | metallothionein 2A | 0.0464973 |
| INTS6 | integrator complex subunit 6 | 0.0435521 |
| EGFR | epidermal growth factor receptor | 0.0398378 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0389566 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0371183 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0336716 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0281644 |
| TAOK3 | TAO kinase 3 | 0.0273408 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0272156 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0271059 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0253338 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0247665 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0241767 |
| CAPRIN2 | caprin family member 2 | 0.0240965 |
| FTL | ferritin, light polypeptide | 0.0239784 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0230196 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0229789 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.022814 |
| PRR16 | proline rich 16 | 0.0223557 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0219304 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0216759 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0215029 |
| S100A9 | S100 calcium binding protein A9 | 0.0208056 |
| RPL26 | ribosomal protein L26 | 0.0206366 |
| HLA-A | major histocompatibility complex, class I, A | 0.019758 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0194657 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0193396 |
| FMNL2 | formin-like 2 | 0.0191364 |
| SMAD6 | SMAD family member 6 | 0.019089 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.018919 |
| FHIT | fragile histidine triad | 0.0187547 |
| USP47 | ubiquitin specific peptidase 47 | 0.0186783 |
| PKP4 | plakophilin 4 | 0.0185955 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0185945 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.018533 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0184067 |
| RPL31 | ribosomal protein L31 | 0.0183445 |
| NRG1 | neuregulin 1 | 0.0182533 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0181615 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0177903 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0177233 |
| FOXO1 | forkhead box O1 | 0.0177008 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0174947 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0174459 |
| RPS29 | ribosomal protein S29 | 0.0172332 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | 0.0172086 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0170456 |
| NAV2 | neuron navigator 2 | 0.0170249 |
| DSPP | dentin sialophosphoprotein | 0.0169135 |
| CMIP | c-Maf inducing protein | 0.0168941 |
| RPL37A | ribosomal protein L37a | 0.0168776 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0168089 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0167884 |
| RSF1 | remodeling and spacing factor 1 | 0.0167579 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0166647 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0166357 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0164428 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0164357 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0164063 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0162539 |
| RPS11 | ribosomal protein S11 | 0.0162162 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0161586 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0160078 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0159919 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0159563 |
| CAB39 | calcium binding protein 39 | 0.0158844 |
| RPS13 | ribosomal protein S13 | 0.0158329 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0156336 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0156162 |
| SYAP1 | synapse associated protein 1 | 0.0155464 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0155351 |
| FN1 | fibronectin 1 | 0.0155145 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0153713 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0152512 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.0151935 |
| SCAMP1 | secretory carrier membrane protein 1 | 0.0148929 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0147333 |
| EXOC4 | exocyst complex component 4 | 0.0145962 |
| CCNK | cyclin K | 0.0144781 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0144635 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0143984 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0143114 |
| CDK14 | cyclin-dependent kinase 14 | 0.0142344 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0142132 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0142075 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0141104 |
| STK39 | serine threonine kinase 39 | 0.0140807 |
| RPS4X | ribosomal protein S4, X-linked | 0.0138756 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0138672 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | 0.013828 |
| DENND5B | DENN/MADD domain containing 5B | 0.0137696 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0136058 |
| ABHD18 | abhydrolase domain containing 18 | 0.0135681 |
| FTO | fat mass and obesity associated | 0.0134595 |
| RIOK3 | RIO kinase 3 | 0.0133935 |
| KIF21A | kinesin family member 21A | 0.0133111 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.103583 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0672271 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0639576 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0639351 |
| ZNF292 | zinc finger protein 292 | -0.0630494 |
| YBX3 | Y box binding protein 3 | -0.0599365 |
| ANKRD28 | ankyrin repeat domain 28 | -0.053722 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0515644 |
| CANX | calnexin | -0.0473104 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0470075 |
| TXNRD1 | thioredoxin reductase 1 | -0.0464565 |
| GNAS | GNAS complex locus | -0.045773 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0442896 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0438764 |
| NUP58 | nucleoporin 58 | -0.043876 |
| TPM4 | tropomyosin 4 | -0.0433884 |
| ANXA2 | annexin A2 | -0.0431385 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0428879 |
| RBM39 | RNA binding motif protein 39 | -0.0428694 |
| OSMR | oncostatin M receptor | -0.0428331 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0426716 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0424761 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0421328 |
| AHNAK | AHNAK nucleoprotein | -0.0419377 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0409775 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0401285 |
| SEPTIN7 | septin 7 | -0.0394226 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0372136 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0370586 |
| SMYD3 | SET and MYND domain containing 3 | -0.0369899 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0367408 |
| SPAG9 | sperm associated antigen 9 | -0.0357339 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0352992 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0351744 |
| TMEM123 | transmembrane protein 123 | -0.0335759 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0335553 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0325746 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0323807 |
| ATM | ATM serine/threonine kinase | -0.0319336 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0310403 |
| SNX14 | sorting nexin 14 | -0.0310171 |
| NF1 | neurofibromin 1 | -0.0309587 |
| LDHA | lactate dehydrogenase A | -0.0306904 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.030683 |
| PTMA | prothymosin, alpha | -0.0305397 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0301523 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0298513 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0296384 |
| CEP290 | centrosomal protein 290kDa | -0.0295753 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0295613 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | -0.0295591 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.029344 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0292227 |
| CDYL | chromodomain protein, Y-like | -0.028417 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0282419 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0282173 |
| PGK1 | phosphoglycerate kinase 1 | -0.028 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0278325 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.027701 |
| WDR45B | WD repeat domain 45B | -0.0276228 |
| PKM | pyruvate kinase, muscle | -0.0271281 |
| ECT2 | epithelial cell transforming 2 | -0.0269307 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.026682 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0264687 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0263468 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0259418 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0258921 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0256736 |
| CRY1 | cryptochrome circadian clock 1 | -0.0248073 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0247748 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0246063 |
| RRBP1 | ribosome binding protein 1 | -0.0245383 |
| DIAPH3 | diaphanous-related formin 3 | -0.0243015 |
| TMEM131 | transmembrane protein 131 | -0.0242095 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0238695 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0238642 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0236936 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0236277 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0235254 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.023341 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0231857 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0230328 |
| YBX1 | Y box binding protein 1 | -0.0226133 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0226034 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.022431 |
| PHF20 | PHD finger protein 20 | -0.0223108 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0222452 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0221401 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0221342 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0221056 |
| SETD5 | SET domain containing 5 | -0.0221026 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0219654 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0219487 |
| CEP95 | centrosomal protein 95kDa | -0.0218773 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0216911 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0216168 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0215914 |
| KIAA1328 | KIAA1328 | -0.0215781 |
| GOLGA4 | golgin A4 | -0.0215246 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0215172 |
