| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allantoin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.18027 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.147693 |
| MT2A | metallothionein 2A | 0.114441 |
| CD44 | CD44 molecule (Indian blood group) | 0.103082 |
| POTEF | POTE ankyrin domain family, member F | 0.0991829 |
| FNDC3B | fibronectin type III domain containing 3B | 0.089639 |
| RUNX1 | runt-related transcription factor 1 | 0.0802341 |
| MAP1B | microtubule-associated protein 1B | 0.0725525 |
| FLNA | filamin A, alpha | 0.0688157 |
| PODXL | podocalyxin-like | 0.0678111 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0643869 |
| GLIS3 | GLIS family zinc finger 3 | 0.0637197 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0632628 |
| PKM | pyruvate kinase, muscle | 0.0630434 |
| NAV1 | neuron navigator 1 | 0.0626776 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0622939 |
| LOC112694756 | uncharaterized LOC112694756 | 0.059556 |
| VCL | vinculin | 0.0536986 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0513347 |
| LDHA | lactate dehydrogenase A | 0.0496872 |
| FBN1 | fibrillin 1 | 0.0446073 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0443386 |
| LOX | lysyl oxidase | 0.0439574 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0436067 |
| COL5A1 | collagen, type V, alpha 1 | 0.040792 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0406756 |
| APP | amyloid beta (A4) precursor protein | 0.0396175 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0381524 |
| MT1X | metallothionein 1X | 0.0378283 |
| DST | dystonin | 0.037756 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0376792 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0367564 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0367138 |
| STC1 | stanniocalcin 1 | 0.0365281 |
| ACTN4 | actinin, alpha 4 | 0.0357845 |
| MYOF | myoferlin | 0.0352907 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0345389 |
| L1CAM | L1 cell adhesion molecule | 0.0340133 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0340131 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0332357 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0328872 |
| MB21D2 | Mab-21 domain containing 2 | 0.0326679 |
| MSN | moesin | 0.0318535 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0318332 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.03163 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0315472 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0311945 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0309074 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0306661 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0301083 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0293695 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0293105 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0288813 |
| CDK6 | cyclin-dependent kinase 6 | 0.0288682 |
| FAT1 | FAT atypical cadherin 1 | 0.028573 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0281388 |
| TPM3 | tropomyosin 3 | 0.0280053 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0279771 |
| GPC6 | glypican 6 | 0.0278848 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0278534 |
| SMAD3 | SMAD family member 3 | 0.0276996 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0276306 |
| COL1A2 | collagen, type I, alpha 2 | 0.0272512 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0271721 |
| TAGLN2 | transgelin 2 | 0.0268096 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0258028 |
| RNF213 | ring finger protein 213 | 0.0257507 |
| HDAC9 | histone deacetylase 9 | 0.0257186 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0253717 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0252053 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0251805 |
| SON | SON DNA binding protein | 0.0251634 |
| MYADM | myeloid-associated differentiation marker | 0.0251012 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0250373 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.024966 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0249004 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0246132 |
| ERBIN | erbb2 interacting protein | 0.024108 |
| TXNRD1 | thioredoxin reductase 1 | 0.0237624 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0236797 |
| FLNB | filamin B, beta | 0.0234118 |
| ANXA2 | annexin A2 | 0.023185 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0231518 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.023066 |
| PLXNA2 | plexin A2 | 0.0226529 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0224693 |
| LOXL2 | lysyl oxidase-like 2 | 0.0224512 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0224048 |
| NOTCH2 | notch 2 | 0.0222619 |
| TENM3 | teneurin transmembrane protein 3 | 0.0222421 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0222115 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0221128 |
| BSG | basigin (Ok blood group) | 0.0219834 |
| COL5A2 | collagen, type V, alpha 2 | 0.021818 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0218064 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0217316 |
| SEPTIN9 | septin 9 | 0.0215968 |
| RTN4 | reticulon 4 | 0.021429 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0213628 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0212009 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.234978 |
| VIM | vimentin | -0.179138 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.140432 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.121471 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104727 |
| PTMA | prothymosin, alpha | -0.0853259 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0736995 |
| S100A6 | S100 calcium binding protein A6 | -0.0697039 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0523856 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.051026 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0458147 |
| FN1 | fibronectin 1 | -0.0455703 |
| CSTB | cystatin B (stefin B) | -0.0429364 |
| CALR | calreticulin | -0.0423889 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0419766 |
| LMNA | lamin A/C | -0.041219 |
| HLA-B | major histocompatibility complex, class I, B | -0.0403252 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0368776 |
| CAVIN1 | caveolae associated protein 1 | -0.0366424 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0361957 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0338535 |
| CANX | calnexin | -0.033643 |
| CDH13 | cadherin 13 | -0.0311181 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0301117 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0300574 |
| S100A10 | S100 calcium binding protein A10 | -0.0298799 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0297286 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0296306 |
| TMSB10 | thymosin beta 10 | -0.0289159 |
| KRT81 | keratin 81, type II | -0.028807 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0283111 |
| THBS2 | thrombospondin 2 | -0.0281877 |
| RPS24 | ribosomal protein S24 | -0.0263353 |
| RPL35A | ribosomal protein L35a | -0.0261202 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0258727 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0253536 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0244568 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0242203 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0239261 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0230429 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0227482 |
| MSI2 | musashi RNA-binding protein 2 | -0.0226057 |
| NDRG1 | N-myc downstream regulated 1 | -0.0224136 |
| GOLGA4 | golgin A4 | -0.0223165 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0222483 |
| SUCNR1 | succinate receptor 1 | -0.0219839 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0217189 |
| RPL37A | ribosomal protein L37a | -0.0216662 |
| INSIG1 | insulin induced gene 1 | -0.0213717 |
| CD109 | CD109 molecule | -0.021316 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0213141 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0204386 |
| RPS27A | ribosomal protein S27a | -0.0199684 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0194568 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0193543 |
| RPS8 | ribosomal protein S8 | -0.0188075 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0186839 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0186183 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0183089 |
| CD63 | CD63 molecule | -0.018193 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0180868 |
| H3-3B | H3.3 histone B | -0.0177782 |
| COL1A1 | collagen, type I, alpha 1 | -0.0177134 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0173514 |
| RPL34 | ribosomal protein L34 | -0.0172384 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.017078 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0170762 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | -0.0170707 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0167142 |
| MMP12 | matrix metallopeptidase 12 | -0.016667 |
| RND3 | Rho family GTPase 3 | -0.016605 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0165895 |
| MEIS2 | Meis homeobox 2 | -0.0160862 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0160084 |
| FTL | ferritin, light polypeptide | -0.0159562 |
| CCND1 | cyclin D1 | -0.0159317 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0155746 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0155556 |
| GDF15 | growth differentiation factor 15 | -0.015189 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0151717 |
| ACTG1 | actin gamma 1 | -0.0149887 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0149386 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0148459 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0147964 |
| TMSB4X | thymosin beta 4, X-linked | -0.0147814 |
| ANKRD30B | ankyrin repeat domain 30B | -0.0146487 |
| IL32 | interleukin 32 | -0.0142559 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0141445 |
| RPL38 | ribosomal protein L38 | -0.0140888 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0140193 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | -0.0139312 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0139302 |
| E2F7 | E2F transcription factor 7 | -0.0139199 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0138382 |
| RPS13 | ribosomal protein S13 | -0.0137674 |
| FRMD4A | FERM domain containing 4A | -0.0136279 |
| GOLGA2 | golgin A2 | -0.013597 |
| MX2 | MX dynamin-like GTPase 2 | -0.0134531 |
| GSTO1 | glutathione S-transferase omega 1 | -0.0134421 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0133146 |
