| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allantoin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NLGN1 | neuroligin 1 | 0.108487 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.106502 |
| CCN2 | cellular communication network factor 2 | 0.0858728 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0841099 |
| AREG | amphiregulin | 0.0781104 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.075983 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0724198 |
| PCBP2 | poly(rC) binding protein 2 | 0.0696649 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0691146 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0680337 |
| YAP1 | Yes-associated protein 1 | 0.061464 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0601054 |
| DST | dystonin | 0.0568598 |
| PTMS | parathymosin | 0.055268 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0491587 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0481214 |
| PCDH7 | protocadherin 7 | 0.048061 |
| MKI67 | marker of proliferation Ki-67 | 0.0468076 |
| CMIP | c-Maf inducing protein | 0.0464293 |
| RTN4 | reticulon 4 | 0.0430631 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0424785 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0418278 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0415138 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0413224 |
| TGM2 | transglutaminase 2 | 0.0400704 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0383948 |
| WWOX | WW domain containing oxidoreductase | 0.0383537 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.038302 |
| VMP1 | vacuole membrane protein 1 | 0.036394 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0359263 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0356362 |
| GSE1 | Gse1 coiled-coil protein | 0.0347374 |
| MPG | N-methylpurine-DNA glycosylase | 0.0345895 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0332762 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0322816 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0321022 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0319563 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0318195 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0313591 |
| ATP11A | ATPase, class VI, type 11A | 0.0313503 |
| XPO1 | exportin 1 | 0.0307781 |
| POTEF | POTE ankyrin domain family, member F | 0.0305163 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0296722 |
| RPL28 | ribosomal protein L28 | 0.0292996 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0290942 |
| BRD4 | bromodomain containing 4 | 0.0290909 |
| TPM3 | tropomyosin 3 | 0.028769 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0284767 |
| CCDC88A | coiled-coil domain containing 88A | 0.0283724 |
| CCND1 | cyclin D1 | 0.027902 |
| ECT2 | epithelial cell transforming 2 | 0.0277143 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.027622 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0276054 |
| HELLS | helicase, lymphoid-specific | 0.0271368 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0269423 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0268386 |
| SEPTIN7 | septin 7 | 0.0266658 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0264767 |
| FUS | FUS RNA binding protein | 0.0264564 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0263881 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0262512 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0260831 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0257882 |
| RPL35A | ribosomal protein L35a | 0.0255897 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0255645 |
| MMP12 | matrix metallopeptidase 12 | 0.0251746 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.025085 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0248084 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0245262 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0241496 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0239515 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0235251 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0234526 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0233955 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0230823 |
| RRM2 | ribonucleotide reductase M2 | 0.0230822 |
| KIF18B | kinesin family member 18B | 0.0228852 |
| TEAD4 | TEA domain family member 4 | 0.0227766 |
| ZNF638 | zinc finger protein 638 | 0.0227525 |
| RPS23 | ribosomal protein S23 | 0.0226056 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0224829 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.0223965 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0223893 |
| RBM25 | RNA binding motif protein 25 | 0.0221187 |
| DIAPH1 | diaphanous-related formin 1 | 0.0219528 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0219524 |
| FASN | fatty acid synthase | 0.0219307 |
| CENPE | centromere protein E, 312kDa | 0.0218952 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.021789 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0217121 |
| AXIN2 | axin 2 | 0.0216467 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0216137 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0214662 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0214547 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0212605 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0211116 |
| CENPF | centromere protein F, 350/400kDa | 0.0211071 |
| PARN | poly(A)-specific ribonuclease | 0.0207448 |
| EDARADD | EDAR-associated death domain | 0.0206243 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0206039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130087 |
| EHBP1 | EH domain binding protein 1 | -0.108238 |
| TPI1 | triosephosphate isomerase 1 | -0.0684996 |
| RPS8 | ribosomal protein S8 | -0.0596467 |
| FTL | ferritin, light polypeptide | -0.0575376 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0572237 |
| RPS3 | ribosomal protein S3 | -0.0561531 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0559003 |
| RPL26 | ribosomal protein L26 | -0.053387 |
| ZNF804A | zinc finger protein 804A | -0.0514024 |
| TMSB10 | thymosin beta 10 | -0.050178 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0494617 |
| JMJD1C | jumonji domain containing 1C | -0.0478236 |
| RPL12 | ribosomal protein L12 | -0.0455063 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0442346 |
| RPL37 | ribosomal protein L37 | -0.0438487 |
| RPL23 | ribosomal protein L23 | -0.041361 |
| PTMA | prothymosin, alpha | -0.0406163 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0403515 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0375769 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0373892 |
| ASPH | aspartate beta-hydroxylase | -0.0366962 |
| RACK1 | receptor for activated C kinase 1 | -0.0351405 |
| RPS12 | ribosomal protein S12 | -0.0344284 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0340963 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0329714 |
| RPS27A | ribosomal protein S27a | -0.0328858 |
| MED13L | mediator complex subunit 13-like | -0.0307088 |
| INTS6 | integrator complex subunit 6 | -0.0306754 |
| VIM | vimentin | -0.0300871 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0298465 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0297344 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0292269 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0289381 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.028847 |
| RPLP0 | ribosomal protein, large, P0 | -0.0272784 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0272671 |
| BCHE | butyrylcholinesterase | -0.0271846 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0268553 |
| RPS17 | ribosomal protein S17 | -0.02664 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0262929 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0261323 |
| HMGA2 | high mobility group AT-hook 2 | -0.0260269 |
| RPL9 | ribosomal protein L9 | -0.0257111 |
| MGAT4C | MGAT4 family, member C | -0.0254261 |
| RPL11 | ribosomal protein L11 | -0.0253663 |
| CDK17 | cyclin-dependent kinase 17 | -0.0253617 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0252912 |
| EPHA5 | EPH receptor A5 | -0.0249895 |
| PCDH9 | protocadherin 9 | -0.024679 |
| ZNF217 | zinc finger protein 217 | -0.024123 |
| KLF6 | Kruppel-like factor 6 | -0.0240608 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.024029 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0239866 |
| MTAP | methylthioadenosine phosphorylase | -0.0239573 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0238876 |
| RPL37A | ribosomal protein L37a | -0.0238447 |
| RPS2 | ribosomal protein S2 | -0.0229405 |
| VPS8 | vacuolar protein sorting 8 homolog (S. cerevisiae) | -0.022916 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.022876 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0224265 |
| RPS24 | ribosomal protein S24 | -0.0222484 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0222321 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0222135 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0220781 |
| NEK7 | NIMA-related kinase 7 | -0.0218467 |
| GCG | glucagon | -0.0215032 |
| RPL34 | ribosomal protein L34 | -0.0214156 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0208664 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0208573 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0207572 |
| LDHA | lactate dehydrogenase A | -0.0204636 |
| DTNA | dystrobrevin, alpha | -0.0204145 |
| PHF3 | PHD finger protein 3 | -0.0201393 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0198629 |
| ANXA1 | annexin A1 | -0.019614 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0193059 |
| RPL5 | ribosomal protein L5 | -0.0192953 |
| SCFD1 | sec1 family domain containing 1 | -0.019291 |
| ABI2 | abl-interactor 2 | -0.0190025 |
| PDCD5 | programmed cell death 5 | -0.0190018 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0189355 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0188355 |
| FSTL5 | follistatin-like 5 | -0.0187881 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0187385 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0186317 |
| RPLP1 | ribosomal protein, large, P1 | -0.018542 |
| LRRC23 | leucine rich repeat containing 23 | -0.0184481 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.018317 |
| S100A6 | S100 calcium binding protein A6 | -0.017762 |
| ANXA2 | annexin A2 | -0.0177054 |
| KSR2 | kinase suppressor of ras 2 | -0.0176897 |
| SYT1 | synaptotagmin I | -0.0175868 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0175763 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0174845 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0173209 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0171882 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0171765 |
| SGCZ | sarcoglycan, zeta | -0.0169532 |
| COMMD10 | COMM domain containing 10 | -0.0169239 |
