| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Allantoin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 0.103896 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0965024 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0923966 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0782703 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0778493 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0728357 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0700009 |
| PKM | pyruvate kinase, muscle | 0.0637033 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0586027 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0578523 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0572683 |
| IFNGR1 | interferon gamma receptor 1 | 0.057182 |
| MT2A | metallothionein 2A | 0.0569514 |
| ERBIN | erbb2 interacting protein | 0.0552052 |
| B2M | beta-2-microglobulin | 0.0528168 |
| AREG | amphiregulin | 0.0520322 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.050848 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0500571 |
| RAD51B | RAD51 paralog B | 0.049913 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0497602 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0497037 |
| LIMA1 | LIM domain and actin binding 1 | 0.0488347 |
| STK24 | serine/threonine kinase 24 | 0.0487248 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0482328 |
| MAP7 | microtubule-associated protein 7 | 0.047897 |
| BCL2L1 | BCL2-like 1 | 0.0462632 |
| SSH2 | slingshot protein phosphatase 2 | 0.0432471 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0426152 |
| VMP1 | vacuole membrane protein 1 | 0.0424439 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.042126 |
| MYO10 | myosin X | 0.041165 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0408179 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0402882 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.040014 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0399679 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0398749 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0378875 |
| RNF43 | ring finger protein 43 | 0.0378568 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0376684 |
| YAP1 | Yes-associated protein 1 | 0.0376584 |
| DIAPH1 | diaphanous-related formin 1 | 0.0375165 |
| TRERF1 | transcriptional regulating factor 1 | 0.0370918 |
| TMC5 | transmembrane channel-like 5 | 0.0370376 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0363548 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0362808 |
| FAT1 | FAT atypical cadherin 1 | 0.0362616 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0360871 |
| DNM2 | dynamin 2 | 0.0355346 |
| PRKCA | protein kinase C, alpha | 0.0351526 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0351155 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0349955 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0341309 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0332047 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.0331672 |
| ASPH | aspartate beta-hydroxylase | 0.0331168 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0330774 |
| PGK1 | phosphoglycerate kinase 1 | 0.0328548 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0326766 |
| NCKAP5 | NCK-associated protein 5 | 0.0325993 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0324157 |
| MLPH | melanophilin | 0.0324039 |
| VCL | vinculin | 0.0323993 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0323452 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0318529 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0306462 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0306014 |
| FTL | ferritin, light polypeptide | 0.0305401 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0303001 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0299618 |
| ATP10B | ATPase, class V, type 10B | 0.0299195 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0297422 |
| CMIP | c-Maf inducing protein | 0.0296727 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0294876 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0294859 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0293916 |
| SEPTIN9 | septin 9 | 0.0291606 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0289838 |
| FMN1 | formin 1 | 0.0288197 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0288147 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0285327 |
| IL20RA | interleukin 20 receptor, alpha | 0.028489 |
| TXNIP | thioredoxin interacting protein | 0.0284649 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0282028 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0279076 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0278813 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0277692 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0277627 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0276067 |
| PCED1B | PC-esterase domain containing 1B | 0.0275416 |
| PTK2 | protein tyrosine kinase 2 | 0.0274802 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0273253 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265406 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0265096 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0264596 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0264086 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0263949 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0262393 |
| SMAD3 | SMAD family member 3 | 0.026195 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0260852 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0260829 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.149348 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137827 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.117275 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.091763 |
| LMO7 | LIM domain 7 | -0.0867788 |
| SQSTM1 | sequestosome 1 | -0.0824043 |
| EZR | ezrin | -0.071058 |
| IRF1 | interferon regulatory factor 1 | -0.0636307 |
| CANX | calnexin | -0.0577851 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0554518 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0536115 |
| MORF4L2 | mortality factor 4 like 2 | -0.0482816 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0469672 |
| CALR | calreticulin | -0.0464176 |
| RRBP1 | ribosome binding protein 1 | -0.0430091 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0426586 |
| HDLBP | high density lipoprotein binding protein | -0.0414174 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0399386 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0394656 |
| AGR2 | anterior gradient 2 | -0.0384192 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0380846 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0376798 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0374326 |
| GOLGB1 | golgin B1 | -0.0356527 |
| RIGI | RNA sensor RIG-I | -0.0352888 |
| AHI1 | Abelson helper integration site 1 | -0.0348932 |
| RAB1A | RAB1A, member RAS oncogene family | -0.034053 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0334853 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0333045 |
| INTS6 | integrator complex subunit 6 | -0.0322916 |
| RNF213 | ring finger protein 213 | -0.0321081 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0314895 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0311323 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0305269 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0301028 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0300819 |
| ARF1 | ADP-ribosylation factor 1 | -0.0290647 |
| TMEM263 | transmembrane protein 263 | -0.0287765 |
| SEC24D | SEC24 family member D | -0.0285872 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0279995 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0262707 |
| DIAPH3 | diaphanous-related formin 3 | -0.0256489 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0250444 |
| CALU | calumenin | -0.0249758 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0249542 |
| GOLGA4 | golgin A4 | -0.0248396 |
| ANXA1 | annexin A1 | -0.0240857 |
| MKI67 | marker of proliferation Ki-67 | -0.0234898 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0234822 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0234588 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | -0.0225564 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0224875 |
| ABLIM1 | actin binding LIM protein 1 | -0.0223385 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0223089 |
| ADIPOR2 | adiponectin receptor 2 | -0.0219709 |
| SEC24A | SEC24 family member A | -0.0217651 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0216028 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0215683 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0215154 |
| MUC20 | mucin 20, cell surface associated | -0.0214568 |
| CENPF | centromere protein F, 350/400kDa | -0.0213592 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | -0.0210315 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0210052 |
| HLA-E | major histocompatibility complex, class I, E | -0.0209501 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0208121 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0206483 |
| ATF6 | activating transcription factor 6 | -0.0203673 |
| GOLGA2 | golgin A2 | -0.0203027 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0201432 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.019416 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0193131 |
| UBC | ubiquitin C | -0.0191547 |
| APOL6 | apolipoprotein L, 6 | -0.019139 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0191319 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0191168 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0190511 |
| HBP1 | HMG-box transcription factor 1 | -0.01888 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0188577 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0188039 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0185668 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0185512 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0185045 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0183706 |
| FUS | FUS RNA binding protein | -0.0183341 |
| NCOA7 | nuclear receptor coactivator 7 | -0.018099 |
| SUCO | SUN domain containing ossification factor | -0.0180599 |
| FDPS | farnesyl diphosphate synthase | -0.017607 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0174463 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0172542 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0171073 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.0170166 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0169611 |
| BRCA2 | breast cancer 2, early onset | -0.016825 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0168097 |
| CD164 | CD164 molecule, sialomucin | -0.0165534 |
| GTF2B | general transcription factor IIB | -0.0165294 |
| JUN | jun proto-oncogene | -0.0165273 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0164428 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.01632 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0162529 |
