| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allantoin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.185266 |
| MT2A | metallothionein 2A | 0.138507 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.138041 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.128142 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.112739 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.111726 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.108559 |
| SVIL | supervillin | 0.0966739 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0722319 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0710183 |
| TMSB10 | thymosin beta 10 | 0.0634465 |
| ATXN1 | ataxin 1 | 0.0608537 |
| FRMD5 | FERM domain containing 5 | 0.0595589 |
| HMGA1 | high mobility group AT-hook 1 | 0.0583426 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0577421 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0550181 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0548578 |
| FOXP1 | forkhead box P1 | 0.0542168 |
| ASPH | aspartate beta-hydroxylase | 0.0509555 |
| BCL2L1 | BCL2-like 1 | 0.0505823 |
| FAM107B | family with sequence similarity 107, member B | 0.0497868 |
| VCL | vinculin | 0.0479848 |
| SMAD3 | SMAD family member 3 | 0.0461475 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0447173 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0429007 |
| RPL37A | ribosomal protein L37a | 0.041869 |
| FAT1 | FAT atypical cadherin 1 | 0.0411773 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0408721 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0397912 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.0376681 |
| RUNX1 | runt-related transcription factor 1 | 0.0372966 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0363983 |
| RPLP1 | ribosomal protein, large, P1 | 0.035023 |
| EGR1 | early growth response 1 | 0.0348592 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0342342 |
| GPC6 | glypican 6 | 0.0337571 |
| RNF213 | ring finger protein 213 | 0.0337172 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0334679 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.033319 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0328739 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0319234 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0318762 |
| RPL23 | ribosomal protein L23 | 0.0309781 |
| RIGI | RNA sensor RIG-I | 0.0307523 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0306867 |
| KYNU | kynureninase | 0.0303657 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0300006 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0298812 |
| HPCAL1 | hippocalcin-like 1 | 0.0298232 |
| KLF6 | Kruppel-like factor 6 | 0.0295921 |
| FLNA | filamin A, alpha | 0.0285127 |
| RPS12 | ribosomal protein S12 | 0.0282734 |
| RPL9 | ribosomal protein L9 | 0.0275991 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0275728 |
| ACTN4 | actinin, alpha 4 | 0.0270498 |
| PALLD | palladin, cytoskeletal associated protein | 0.0266652 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0266338 |
| RPL27 | ribosomal protein L27 | 0.0265844 |
| MCL1 | myeloid cell leukemia 1 | 0.0263036 |
| MYO1E | myosin IE | 0.0261603 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0259532 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0255866 |
| ITGB5 | integrin, beta 5 | 0.025488 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0254138 |
| RPS19 | ribosomal protein S19 | 0.0253303 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0246557 |
| DIAPH1 | diaphanous-related formin 1 | 0.0245908 |
| H1-0 | H1.0 linker histone | 0.0245145 |
| HDAC4 | histone deacetylase 4 | 0.0243927 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.0242679 |
| RASA2 | RAS p21 protein activator 2 | 0.0240809 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0239522 |
| JAG1 | jagged 1 | 0.0237887 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0237384 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0234409 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0232265 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0231457 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0231315 |
| NDRG1 | N-myc downstream regulated 1 | 0.0229076 |
| SP100 | SP100 nuclear antigen | 0.0227436 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0225838 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0223623 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.022229 |
| ACTN1 | actinin, alpha 1 | 0.0218659 |
| DST | dystonin | 0.0218367 |
| RPL37 | ribosomal protein L37 | 0.0215305 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0213236 |
| ITGAV | integrin, alpha V | 0.0211938 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0211174 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0208319 |
| RPS8 | ribosomal protein S8 | 0.020831 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0207701 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0207278 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0205824 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0204819 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0203086 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0202094 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0201463 |
| RSU1 | Ras suppressor protein 1 | 0.0200585 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0199984 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.223111 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.201588 |
| APOB | apolipoprotein B | -0.15238 |
| FNDC3B | fibronectin type III domain containing 3B | -0.110175 |
| C3 | complement component 3 | -0.103211 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0907803 |
| APOA2 | apolipoprotein A-II | -0.0865413 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0864726 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0802994 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0751484 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0737297 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0706082 |
| A2M | alpha-2-macroglobulin | -0.0702942 |
| LYZ | lysozyme | -0.0694514 |
| TMEM123 | transmembrane protein 123 | -0.0668911 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0664378 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0662891 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0658975 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0642901 |
| TRIM26 | tripartite motif containing 26 | -0.0642238 |
| AHSG | alpha-2-HS-glycoprotein | -0.0590671 |
| RPS6 | ribosomal protein S6 | -0.0570608 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0538543 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0529865 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0524521 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0520579 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0503917 |
| CPE | carboxypeptidase E | -0.050153 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0484856 |
| PCBP2 | poly(rC) binding protein 2 | -0.0459386 |
| JMJD1C | jumonji domain containing 1C | -0.0453401 |
| GOLGA4 | golgin A4 | -0.044814 |
| RBM39 | RNA binding motif protein 39 | -0.0441462 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0440176 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0425272 |
| CP | ceruloplasmin (ferroxidase) | -0.0425089 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0417453 |
| INSIG2 | insulin induced gene 2 | -0.0408775 |
| FN1 | fibronectin 1 | -0.0401572 |
| DENND4A | DENN/MADD domain containing 4A | -0.0389087 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0384496 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0380394 |
| TF | transferrin | -0.0373766 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.037374 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0360145 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0360096 |
| PEG3 | paternally expressed 3 | -0.0353289 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0347656 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0347111 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0344975 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.0342482 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.0333502 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0333452 |
| PEG10 | paternally expressed 10 | -0.0319581 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0317607 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0314931 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0312153 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0309202 |
| AFDN | afadin, adherens junction formation factor | -0.030042 |
| CALR | calreticulin | -0.0300175 |
| GPC3 | glypican 3 | -0.0296818 |
| HELZ | helicase with zinc finger | -0.0296335 |
| KIF5B | kinesin family member 5B | -0.0291571 |
| PTK2 | protein tyrosine kinase 2 | -0.0287003 |
| OLA1 | Obg-like ATPase 1 | -0.0284932 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0281734 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0281216 |
| IGF2 | insulin-like growth factor 2 | -0.0280103 |
| MATR3 | matrin 3 | -0.0276882 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0276743 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0273119 |
| PCM1 | pericentriolar material 1 | -0.0271788 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0268741 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0264736 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0264331 |
| QKI | QKI, KH domain containing, RNA binding | -0.0263833 |
| SELENOP | selenoprotein P | -0.0262073 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.025717 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0254998 |
| KIF1B | kinesin family member 1B | -0.0253176 |
| CCNL1 | cyclin L1 | -0.0252079 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0249555 |
| PERP | PERP, TP53 apoptosis effector | -0.0249 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0247279 |
| USP3 | ubiquitin specific peptidase 3 | -0.0245914 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0245375 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.024501 |
| PLIN2 | perilipin 2 | -0.0243521 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0243422 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.024251 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0241263 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0240516 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0240495 |
| TMEM51 | transmembrane protein 51 | -0.023871 |
| LRRC1 | leucine rich repeat containing 1 | -0.0238495 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0238226 |
| MATN3 | matrilin 3 | -0.0236151 |
| WDR45B | WD repeat domain 45B | -0.0235752 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0233851 |
| RLF | rearranged L-myc fusion | -0.0232803 |
