| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allantoin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.156647 |
| MT2A | metallothionein 2A | 0.120132 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.11645 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.113664 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.112004 |
| HMGA2 | high mobility group AT-hook 2 | 0.103061 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0972026 |
| TGM2 | transglutaminase 2 | 0.0948082 |
| SMAD3 | SMAD family member 3 | 0.092735 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0759531 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.073522 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0733901 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0676858 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0669577 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0591226 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0586676 |
| FAM20C | family with sequence similarity 20, member C | 0.0585271 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0565696 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0506942 |
| PKM | pyruvate kinase, muscle | 0.0498453 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0483302 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0481082 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0466927 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.044213 |
| HMGA1 | high mobility group AT-hook 1 | 0.0441786 |
| FTL | ferritin, light polypeptide | 0.0435855 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0431182 |
| LOXL2 | lysyl oxidase-like 2 | 0.0430801 |
| MYO10 | myosin X | 0.0420293 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0415455 |
| NTN4 | netrin 4 | 0.0408687 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0406367 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0404298 |
| NRG1 | neuregulin 1 | 0.0403097 |
| MTSS1 | metastasis suppressor 1 | 0.0398572 |
| ANGPTL4 | angiopoietin-like 4 | 0.0382793 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0368597 |
| RPS19 | ribosomal protein S19 | 0.0366161 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0357046 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0352309 |
| PCBP2 | poly(rC) binding protein 2 | 0.0351628 |
| TMSB10 | thymosin beta 10 | 0.0347821 |
| ECE1 | endothelin converting enzyme 1 | 0.0344348 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0341824 |
| SEPTIN9 | septin 9 | 0.0341211 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0335918 |
| NAV1 | neuron navigator 1 | 0.0335351 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0334069 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.032658 |
| TGFB1 | transforming growth factor, beta 1 | 0.0326141 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0322788 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0312659 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0312212 |
| NDRG1 | N-myc downstream regulated 1 | 0.0308989 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.030616 |
| WLS | wntless Wnt ligand secretion mediator | 0.0292683 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.028592 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0282412 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0278316 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0277905 |
| RPLP1 | ribosomal protein, large, P1 | 0.0272841 |
| CLMP | CXADR-like membrane protein | 0.0272266 |
| RNF213 | ring finger protein 213 | 0.0265705 |
| RNF144A | ring finger protein 144A | 0.0261939 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0260266 |
| FLNA | filamin A, alpha | 0.0259141 |
| ZNF469 | zinc finger protein 469 | 0.025417 |
| NRP1 | neuropilin 1 | 0.0251642 |
| RPL36 | ribosomal protein L36 | 0.0251255 |
| KSR1 | kinase suppressor of ras 1 | 0.0250989 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.025074 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0250688 |
| PRKCA | protein kinase C, alpha | 0.0249294 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0246783 |
| DNER | delta/notch-like EGF repeat containing | 0.0246398 |
| POTEF | POTE ankyrin domain family, member F | 0.0245259 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0242505 |
| FHL2 | four and a half LIM domains 2 | 0.0239002 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0238624 |
| HDAC4 | histone deacetylase 4 | 0.0237311 |
| CDK6 | cyclin-dependent kinase 6 | 0.0234927 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0234428 |
| SVIL | supervillin | 0.0233211 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0230694 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0223395 |
| GLIS3 | GLIS family zinc finger 3 | 0.0223361 |
| LOX | lysyl oxidase | 0.0222427 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0222045 |
| B2M | beta-2-microglobulin | 0.0221889 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0217824 |
| MT1X | metallothionein 1X | 0.021357 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0212455 |
| TMEM164 | transmembrane protein 164 | 0.0208711 |
| PRSS23 | protease, serine, 23 | 0.0208548 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0208247 |
| ATXN1 | ataxin 1 | 0.0206024 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0204398 |
| CUX1 | cut-like homeobox 1 | 0.0203998 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0203717 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0201101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.186003 |
| GOLGA4 | golgin A4 | -0.141118 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.115673 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0988502 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0872984 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0768608 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0718599 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0714454 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0627497 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0625286 |
| OSMR | oncostatin M receptor | -0.0602241 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0558621 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0508437 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0507311 |
| RBM39 | RNA binding motif protein 39 | -0.0499767 |
| COPA | coatomer protein complex, subunit alpha | -0.0490695 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.047328 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0466661 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0465627 |
| CANX | calnexin | -0.0465313 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0462058 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0453973 |
| CALU | calumenin | -0.0429808 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0427185 |
| SETD5 | SET domain containing 5 | -0.0424688 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0420595 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0418071 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0415368 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0414968 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0405072 |
| SRP54 | signal recognition particle 54kDa | -0.0402439 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0395398 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0394311 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0390081 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.038968 |
| LRRC49 | leucine rich repeat containing 49 | -0.0387928 |
| USP34 | ubiquitin specific peptidase 34 | -0.038721 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0383327 |
| SPAG9 | sperm associated antigen 9 | -0.0382186 |
| HDLBP | high density lipoprotein binding protein | -0.0375337 |
| TMEM263 | transmembrane protein 263 | -0.0366264 |
| COG5 | component of oligomeric golgi complex 5 | -0.035935 |
| NBAS | neuroblastoma amplified sequence | -0.0358292 |
| HM13 | histocompatibility (minor) 13 | -0.0356964 |
| SEPTIN2 | septin 2 | -0.0356394 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0354414 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0352821 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0351634 |
| NF1 | neurofibromin 1 | -0.0347742 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.034533 |
| SUCO | SUN domain containing ossification factor | -0.0341129 |
| YME1L1 | YME1-like 1 ATPase | -0.0338387 |
| USP15 | ubiquitin specific peptidase 15 | -0.0330915 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0328336 |
| OGA | O-GlcNAcase | -0.0323324 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0323252 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.032119 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0319083 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0318052 |
| GOLGA3 | golgin A3 | -0.0315876 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0314752 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0314191 |
| SEC24A | SEC24 family member A | -0.0312047 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0310545 |
| SBF2 | SET binding factor 2 | -0.0303263 |
| MORF4L2 | mortality factor 4 like 2 | -0.0302579 |
| SEC24D | SEC24 family member D | -0.0301598 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0299073 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0299073 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0297473 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0297173 |
| NGLY1 | N-glycanase 1 | -0.0292491 |
| MEF2A | myocyte enhancer factor 2A | -0.0292238 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0291219 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0291105 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0283967 |
| DENND4A | DENN/MADD domain containing 4A | -0.0281192 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0281069 |
| CD109 | CD109 molecule | -0.027979 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0276674 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0276194 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0275629 |
| USP3 | ubiquitin specific peptidase 3 | -0.0275014 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0271993 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.026605 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0266002 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0265037 |
| HDAC9 | histone deacetylase 9 | -0.0261369 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0259181 |
| OXSR1 | oxidative stress responsive 1 | -0.0255868 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.025577 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0254298 |
| FNIP1 | folliculin interacting protein 1 | -0.0254234 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0252038 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0245009 |
| ATP13A3 | ATPase type 13A3 | -0.0243358 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0242751 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0239669 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0236519 |
| AHR | aryl hydrocarbon receptor | -0.0236442 |
