| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allantoin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.270653 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.217494 |
| GRAMD1B | GRAM domain containing 1B | 0.195737 |
| MT2A | metallothionein 2A | 0.194891 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.120558 |
| EGR1 | early growth response 1 | 0.0905326 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0743383 |
| MCL1 | myeloid cell leukemia 1 | 0.0712258 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0711009 |
| TXNRD1 | thioredoxin reductase 1 | 0.069017 |
| WWOX | WW domain containing oxidoreductase | 0.0670325 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0620167 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0550738 |
| CMIP | c-Maf inducing protein | 0.0517445 |
| KYNU | kynureninase | 0.0516962 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0446331 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0438236 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0431655 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0431611 |
| LAMA5 | laminin, alpha 5 | 0.0407466 |
| TMSB10 | thymosin beta 10 | 0.0401441 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0401223 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0396098 |
| HDAC9 | histone deacetylase 9 | 0.0394799 |
| VMP1 | vacuole membrane protein 1 | 0.0340748 |
| PDE10A | phosphodiesterase 10A | 0.0328273 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0327913 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0327041 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0326082 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0322652 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0319051 |
| HLA-A | major histocompatibility complex, class I, A | 0.0313439 |
| NRG1 | neuregulin 1 | 0.0308867 |
| MT1X | metallothionein 1X | 0.0307911 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0305373 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0302973 |
| SVIL | supervillin | 0.0300688 |
| POTEF | POTE ankyrin domain family, member F | 0.0299895 |
| PKM | pyruvate kinase, muscle | 0.0295198 |
| RAD51B | RAD51 paralog B | 0.029023 |
| BRD2 | bromodomain containing 2 | 0.0288562 |
| ACTN1 | actinin, alpha 1 | 0.0274522 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0269933 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0262372 |
| TPI1 | triosephosphate isomerase 1 | 0.0260673 |
| FLNA | filamin A, alpha | 0.0260055 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0256951 |
| HMOX1 | heme oxygenase 1 | 0.025083 |
| NTN4 | netrin 4 | 0.0250715 |
| STC1 | stanniocalcin 1 | 0.0245261 |
| OSMR | oncostatin M receptor | 0.0242506 |
| GLIS3 | GLIS family zinc finger 3 | 0.0236412 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0235444 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0232668 |
| ATXN1 | ataxin 1 | 0.0232444 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0232118 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0231618 |
| KLF6 | Kruppel-like factor 6 | 0.0230749 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0229866 |
| PLS3 | plastin 3 | 0.0227923 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0224624 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0220384 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0215872 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0214087 |
| IL6 | interleukin 6 | 0.0211544 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0211245 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0205983 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0205637 |
| MSN | moesin | 0.0204239 |
| IER2 | immediate early response 2 | 0.0202256 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0200656 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0198982 |
| BMP6 | bone morphogenetic protein 6 | 0.0189317 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0188729 |
| HMGA1 | high mobility group AT-hook 1 | 0.0187564 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.018548 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0184476 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0183 |
| AXL | AXL receptor tyrosine kinase | 0.0181685 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0177939 |
| ANGPTL4 | angiopoietin-like 4 | 0.017553 |
| RNF213 | ring finger protein 213 | 0.0173209 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0170774 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0170134 |
| RRM2 | ribonucleotide reductase M2 | 0.0168464 |
| GPATCH2L | G patch domain containing 2-like | 0.0167331 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0164942 |
| RCOR1 | REST corepressor 1 | 0.0164848 |
| NABP1 | nucleic acid binding protein 1 | 0.0164464 |
| LOC112694756 | uncharaterized LOC112694756 | 0.016419 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0164091 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0163946 |
| EXOC6B | exocyst complex component 6B | 0.0162803 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0162674 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0162153 |
| ATF6 | activating transcription factor 6 | 0.0161093 |
| FTL | ferritin, light polypeptide | 0.0159435 |
| ZNF277 | zinc finger protein 277 | 0.0158657 |
| LDHA | lactate dehydrogenase A | 0.0154966 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0154676 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.206066 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178375 |
| VIM | vimentin | -0.138974 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128088 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106909 |
| ACTG1 | actin gamma 1 | -0.0694735 |
| PTMA | prothymosin, alpha | -0.0666061 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0636398 |
| FMNL2 | formin-like 2 | -0.0617069 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0615189 |
| IER3 | immediate early response 3 | -0.0606911 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0582481 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0544621 |
| S100A10 | S100 calcium binding protein A10 | -0.0530095 |
| ERBIN | erbb2 interacting protein | -0.0520645 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0512797 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0480821 |
| RPL35A | ribosomal protein L35a | -0.0455918 |
| CAVIN1 | caveolae associated protein 1 | -0.0439594 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0432944 |
| IGF2 | insulin-like growth factor 2 | -0.0385559 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0385146 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0382826 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0380758 |
| AHNAK | AHNAK nucleoprotein | -0.0366184 |
| S100A6 | S100 calcium binding protein A6 | -0.0358239 |
| APP | amyloid beta (A4) precursor protein | -0.0354945 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0354236 |
| MATR3 | matrin 3 | -0.0352496 |
| TPD52 | tumor protein D52 | -0.0352146 |
| RBM39 | RNA binding motif protein 39 | -0.0346546 |
| PYGL | phosphorylase, glycogen, liver | -0.0340853 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0334637 |
| CFDP1 | craniofacial development protein 1 | -0.0328649 |
| GOLGA4 | golgin A4 | -0.0326883 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0325945 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0322439 |
| CALR | calreticulin | -0.0320486 |
| CANX | calnexin | -0.0320187 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0319705 |
| TLK1 | tousled-like kinase 1 | -0.0316647 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0309689 |
| PARD3 | par-3 family cell polarity regulator | -0.0307701 |
| ANXA2 | annexin A2 | -0.0305443 |
| ZNF292 | zinc finger protein 292 | -0.030388 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0301472 |
| USP3 | ubiquitin specific peptidase 3 | -0.0298476 |
| KIF5B | kinesin family member 5B | -0.0297765 |
| RPS24 | ribosomal protein S24 | -0.0295706 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0293912 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0293005 |
| TPM3 | tropomyosin 3 | -0.0292911 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0292596 |
| RPS27A | ribosomal protein S27a | -0.0290873 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0287236 |
| FNBP1L | formin binding protein 1-like | -0.0286504 |
| RPS25 | ribosomal protein S25 | -0.0284731 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0276812 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0273225 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0273217 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0272279 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0271364 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0269619 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0265817 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0265239 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0262131 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0260171 |
| RPS6 | ribosomal protein S6 | -0.0256177 |
| S100A9 | S100 calcium binding protein A9 | -0.025478 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0253482 |
| SRGN | serglycin | -0.0252944 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0250608 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0249305 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.024801 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0244063 |
| FUS | FUS RNA binding protein | -0.0241325 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0239116 |
| ZFR | zinc finger RNA binding protein | -0.0238306 |
| FBXO11 | F-box protein 11 | -0.0234648 |
| TPM4 | tropomyosin 4 | -0.0234539 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.023384 |
| GLG1 | golgi glycoprotein 1 | -0.0233474 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0232557 |
| RNF145 | ring finger protein 145 | -0.0232305 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0230654 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0230427 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0229218 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0228061 |
| RPS5 | ribosomal protein S5 | -0.022521 |
| RPS15 | ribosomal protein S15 | -0.0224054 |
| SEPTIN7 | septin 7 | -0.0223125 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0223069 |
| NOP58 | NOP58 ribonucleoprotein | -0.0222611 |
| GNAS | GNAS complex locus | -0.0222334 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0221687 |
| SHTN1 | shootin 1 | -0.0219856 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0216037 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0208643 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0208309 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0207971 |
