| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Allantoin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Allantoin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.238757 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.126619 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0953738 |
| TXNRD1 | thioredoxin reductase 1 | 0.0936239 |
| POTEF | POTE ankyrin domain family, member F | 0.0932359 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.09292 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0907396 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0795074 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0658973 |
| EGR1 | early growth response 1 | 0.0658309 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0650635 |
| PCBP2 | poly(rC) binding protein 2 | 0.0640824 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0635144 |
| TPM3 | tropomyosin 3 | 0.0612958 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0552846 |
| TPI1 | triosephosphate isomerase 1 | 0.054817 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0530773 |
| GRAMD1B | GRAM domain containing 1B | 0.053068 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0525877 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0517326 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0512549 |
| RRM2 | ribonucleotide reductase M2 | 0.0491475 |
| VIM | vimentin | 0.046627 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0465722 |
| PKM | pyruvate kinase, muscle | 0.0438906 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0416497 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0403275 |
| PDE10A | phosphodiesterase 10A | 0.0395914 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0392245 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0391293 |
| UBC | ubiquitin C | 0.0387755 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.0385502 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0376782 |
| BRD2 | bromodomain containing 2 | 0.0371847 |
| WWOX | WW domain containing oxidoreductase | 0.036448 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0361306 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0358969 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0353342 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0343598 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0336531 |
| VCL | vinculin | 0.0335937 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0332062 |
| FLNA | filamin A, alpha | 0.0327289 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0324424 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0322329 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0320851 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0313864 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0308194 |
| STC1 | stanniocalcin 1 | 0.0307263 |
| SET | SET nuclear proto-oncogene | 0.0306021 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0304189 |
| CLTC | clathrin, heavy chain (Hc) | 0.0303549 |
| ENO1 | enolase 1, (alpha) | 0.0300271 |
| HOMER1 | homer scaffolding protein 1 | 0.0298681 |
| PTMS | parathymosin | 0.0293773 |
| PFN1 | profilin 1 | 0.0291063 |
| NUP155 | nucleoporin 155kDa | 0.0289718 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0289562 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0288421 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0287505 |
| LDHB | lactate dehydrogenase B | 0.0286409 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0286209 |
| ACTG1 | actin gamma 1 | 0.0280075 |
| IPO7 | importin 7 | 0.0279248 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0279186 |
| TUBA1B | tubulin, alpha 1b | 0.0277405 |
| MYPN | myopalladin | 0.0275678 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0272871 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0272035 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0269949 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0269758 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0268216 |
| YBX1 | Y box binding protein 1 | 0.0267065 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0267016 |
| HCFC1 | host cell factor C1 | 0.0264269 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0260741 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0258746 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0254506 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0250419 |
| TWF1 | twinfilin actin binding protein 1 | 0.0249583 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0245317 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0244079 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0243778 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0242847 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0241871 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0241445 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.023729 |
| ADAR | adenosine deaminase, RNA-specific | 0.0232407 |
| FOXM1 | forkhead box M1 | 0.0232315 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.0232195 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0232183 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0231214 |
| MEF2D | myocyte enhancer factor 2D | 0.0229251 |
| LDHA | lactate dehydrogenase A | 0.0226646 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0226299 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0225084 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0223754 |
| HMGA1 | high mobility group AT-hook 1 | 0.0223313 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0220529 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.021914 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0921329 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0826812 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0782911 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0702967 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0679403 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0676005 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.067111 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0660297 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0620266 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0600701 |
| RAD51B | RAD51 paralog B | -0.0588402 |
| RSF1 | remodeling and spacing factor 1 | -0.0479457 |
| PTMA | prothymosin, alpha | -0.0460824 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0458776 |
| FMNL2 | formin-like 2 | -0.0453742 |
| ATXN1 | ataxin 1 | -0.0452513 |
| COPA | coatomer protein complex, subunit alpha | -0.0451097 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.044078 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0431717 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0425625 |
| RPS3 | ribosomal protein S3 | -0.0423468 |
| RPL35A | ribosomal protein L35a | -0.0412363 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0410231 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0401335 |
| CANX | calnexin | -0.0392337 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0388931 |
| NF1 | neurofibromin 1 | -0.0386848 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0381824 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0381533 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0378751 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0376115 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.037365 |
| MAP4 | microtubule-associated protein 4 | -0.0359605 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0359522 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0355564 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0351921 |
| GOLGB1 | golgin B1 | -0.0337432 |
| YBX3 | Y box binding protein 3 | -0.0336804 |
| RPL37A | ribosomal protein L37a | -0.0335295 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0334889 |
| RBM39 | RNA binding motif protein 39 | -0.0324561 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.031938 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0316822 |
| NABP1 | nucleic acid binding protein 1 | -0.0316662 |
| PTK2 | protein tyrosine kinase 2 | -0.0316352 |
| RPL34 | ribosomal protein L34 | -0.0315656 |
| HMGA2 | high mobility group AT-hook 2 | -0.0313812 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0312369 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.030884 |
| EGFR | epidermal growth factor receptor | -0.0303568 |
| TMEM165 | transmembrane protein 165 | -0.0302136 |
| CD2AP | CD2-associated protein | -0.0300803 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.029919 |
| RPL31 | ribosomal protein L31 | -0.0298217 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0297877 |
| HLA-B | major histocompatibility complex, class I, B | -0.0295247 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0294388 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0290962 |
| CAVIN1 | caveolae associated protein 1 | -0.0280032 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0277003 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0273356 |
| MFSD4B | major facilitator superfamily domain containing 4B | -0.0271377 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0271367 |
| BBX | bobby sox homolog (Drosophila) | -0.0271099 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0269922 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.026779 |
| SBF2 | SET binding factor 2 | -0.0267112 |
| AEBP2 | AE binding protein 2 | -0.026496 |
| LOXL2 | lysyl oxidase-like 2 | -0.0263965 |
| MT2A | metallothionein 2A | -0.026374 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0256618 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0253783 |
| RPS8 | ribosomal protein S8 | -0.0253713 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0252797 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0251255 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0249879 |
| COG6 | component of oligomeric golgi complex 6 | -0.0247146 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0245387 |
| TLK1 | tousled-like kinase 1 | -0.0245106 |
| FNIP1 | folliculin interacting protein 1 | -0.024269 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0239432 |
| ATF6 | activating transcription factor 6 | -0.0239147 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0239035 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0234363 |
| TMEM263 | transmembrane protein 263 | -0.0233222 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0231574 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0230167 |
| RPS27 | ribosomal protein S27 | -0.0229368 |
| RPL26 | ribosomal protein L26 | -0.0226333 |
| DOCK7 | dedicator of cytokinesis 7 | -0.022578 |
| EHBP1 | EH domain binding protein 1 | -0.0225494 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0225223 |
| RPL37 | ribosomal protein L37 | -0.0222114 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0220265 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.02201 |
| SRP72 | signal recognition particle 72kDa | -0.0219936 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0219515 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0218683 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0218077 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0216743 |
